Seven samples of ergometrine maleate injection were taken from current stock in Central Medical Stores in Banjul (Gambia), Khartoum (Sudan) and Harare (Zimbabwe), 22 samples were taken from 13 different district hospitals in Malawi, Sudan and Zimbabwe. The 29 samples were produced by 10 different manufacturers from 6 countries; 25 samples were imported. Full details of all samples are given in Annex 1. Six samples of oxytocin injection, all imported from the same manufacturer, were taken from five district hospitals in Zimbabwe.
Two batches each of three brands of ergometrine maleate injection were included in the simulation study. This selection covers all major suppliers of UNICEF and IDA. In addition, two batches of specially produced ergometrine maleate injection were included for a controlled comparison of their stability with similar solutions of methylergometrine injection, A total of 392 samples were analyzed. Two batches each of three brands of methylergometrine maleate injection, representing the major suppliers to UNICEF and IDA, were included plus two batches specially produced for a controlled comparison with ergometrine. A total of 392 samples were analyzed. Two batches each of three brands of oxytocin injection, representing the major suppliers of UNICEF and IDA, were included in the study, A total of 180 samples were analyzed.