Product name:

Sertindole

CAS number:

106516-24-9

Synonyms:

Lu-23-174; 1-(2-{4-[5-chloro-1-(p-fluorophenyl)indol-3-yl]piperidine}ethyl)2- imidazolidinone

Country

Effective Date

Description of action taken
Grounds for decision

Bulgaria

The Bulgarian Drug Agency in the Ministry of Health withdrew the atypical antipsychotic agent sertindole (serdolect) because of serious adverse reactions worldwide. (Reference: Communication to WHO from the Bulgarian Drug Agency, Ministry of Health, Bulgaria.)

United Kingdom

December 1998

The manufacturer of the antipsychotic medication, sertindole (serdolect) voluntarily suspended the availability of serdolect. This is because of concerns about reports of cardiac arrhythmias and sudden cardiac death associated with its use. (Reference: Message from Committee on Safety of Medicines, 2 December 1998.)