During the first clinical episode of genital herpes, treat with oral acyclovir.

Vaginal delivery in women who develop primary genital herpes shortly before delivery puts babies at risk for neonatal herpes. Babies born to women with recurrent disease are at very low risk. Genital cultures late in pregnancy are poor predictors of shedding during delivery. Careful history and physical examination serve as a guide to the need for caesarean section in mothers with genital herpes lesions.

Treatment for Neonates

• acyclovir, 10 mg/kg intravenously three times a day, for 10-21 days