Chromomycosis, which is caused by fungi of several genera, including Fonsecaea and Cladosporium, is a chronic infection of exposed areas such as the lower leg. Papular lesions, which appear first on the feet and extent slowly upwards, gradually become nodular and eventually develop into large wart-like lesions.

Treatment

Small lesions can be removed surgically, although this is not usually recommended because of the risk of local recurrence. The local application of heat may improve lesions. Oral itraconazole, 200-400 mg daily, and flucytosine 150 mg/kg in four divided doses daily, are often effective and can be given either alone or in combination.