Lotion, 10%

General information

A benzimidazole derivative that inhibits cellular enzyme systems specific to various helminths.

Clinical information

Uses

Treatment of creeping eruptions due to Ancylostoma spp. (cutaneous larva migrans).

Dosage and administration

Adults and children: lotion should be applied liberally over the tract of the larvae twice or three times daily for 7-10 days.

Contraindications

Known hypersensitivity.

Precautions

Treatment should be suspended immediately should a rash or any other signs of hypersensitivity occur.

Use in pregnancy

Tiabendazole has been shown experimentally to have teratogenic potential. Treatment should preferably be deferred until after delivery.

Adverse effects

Systemic toxicity rarely occurs after topical application.

Storage

Lotion should be kept in tightly closed containers.