Guide to Good Prescribing - A Practical Manual
(1994; 115 pages) [French] [Spanish] View the PDF document
Table of Contents
View the documentAcknowledgments
View the documentWhy you need this book
Open this folder and view contentsPart 1: Overview
Open this folder and view contentsPart 2: Selecting your P(ersonal) drugs
Open this folder and view contentsPart 3: Treating your patients
Open this folder and view contentsPart 4: Keeping up-to-date
Close this folderAnnexes
Close this folderAnnex 1: Essentials of pharmacology in daily practice
View the documentIntroduction
Open this folder and view contentsPharmacodynamics
Close this folderPharmacokinetics
View the documentThe Cp/time curve with a therapeutic window
Open this folder and view contentsDrug treatment
Open this folder and view contentsSpecial features of the curve
View the documentAnnex 2: Essential references
Open this folder and view contentsAnnex 3: How to explain the use of some dosage forms
Open this folder and view contentsAnnex 4. The use of injections
View the documentBack Cover
 

Pharmacokinetics

A dose is usually repeated over a certain period. The plasma concentration in one or more patients during a certain period is depicted in a so called plasma concentration/time curve (Cp/time curve). Figure 11 shows the Cp/time curve of the first 7 days after starting treatment.


Figure 11: Cp/time curve

The shape of the Cp/time curves is defined by pharmacokinetic factors. The relationship between dose and plasma concentration is linear. This implies that if the dose is doubled, the steady state plasma concentration is also doubled (Figure 12).


Figure 12: Cp/time curve, dose doubled

to previous section
to next section
 
 
The WHO Essential Medicines and Health Products Information Portal was designed and is maintained by Human Info NGO. Last updated: June 25, 2014