Guide to Good Prescribing - A Practical Manual
(1994; 115 pages) [French] [Spanish] View the PDF document
Table of Contents
View the documentAcknowledgments
View the documentWhy you need this book
Open this folder and view contentsPart 1: Overview
Open this folder and view contentsPart 2: Selecting your P(ersonal) drugs
Open this folder and view contentsPart 3: Treating your patients
Open this folder and view contentsPart 4: Keeping up-to-date
Close this folderAnnexes
Close this folderAnnex 1: Essentials of pharmacology in daily practice
View the documentIntroduction
Open this folder and view contentsPharmacodynamics
Open this folder and view contentsPharmacokinetics
Open this folder and view contentsDrug treatment
Open this folder and view contentsSpecial features of the curve
View the documentAnnex 2: Essential references
Open this folder and view contentsAnnex 3: How to explain the use of some dosage forms
Open this folder and view contentsAnnex 4. The use of injections
View the documentBack Cover
 

Introduction

Pharmacology describes the interaction between drugs and organisms. In this interaction two features are especially important. Pharmacodynamics deals with the effects of a drug on the body; how a drug acts and its side effects, in which tissues, at which receptor sites, at which concentration, etc. The effects of drugs may be altered by other drugs or disease states. Antagonism, synergism, addition and other phenomena are also described by pharmacodynamics. Pharmacokinetics deals with the effects of the body on the drug, through Absorption, Distribution, Metabolism and Excretion (ADME).

The dynamics and kinetics of a drug determine its therapeutic usefulness. The pharmacodynamics of a drug determine its effectiveness and which side effects may occur, and at what concentration. The prescriber has very little influence on this. The pharmacokinetics of a drug determine how often, in what quantity and dosage form and for how long the drug should be given to reach and maintain the required plasma concentration. As the prescriber can actively influence the process, the following section concentrates on this aspect.

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