Guide to Good Prescribing - A Practical Manual
(1994; 115 pages) [French] [Spanish] View the PDF document
Table of Contents
View the documentAcknowledgments
View the documentWhy you need this book
Open this folder and view contentsPart 1: Overview
Close this folderPart 2: Selecting your P(ersonal) drugs
View the documentChapter 2. Introduction to P-drugs
View the documentChapter 3. Example of selecting a P-drug: angina pectoris
Close this folderChapter 4. Guidelines for selecting P-drugs
View the documentStep i: Define the diagnosis
View the documentStep ii: Specify the therapeutic objective
View the documentStep iii: Make an inventory of effective groups of drugs
View the documentStep iv: Choose an effective group according to criteria
View the documentStep v: Choose a P-drug
View the documentChapter 5. P-drug and P-treatment
Open this folder and view contentsPart 3: Treating your patients
Open this folder and view contentsPart 4: Keeping up-to-date
Open this folder and view contentsAnnexes
View the documentBack Cover
 

Step iii: Make an inventory of effective groups of drugs

In this step you link the therapeutic objective to various drugs. Drugs that are not effective are not worth examining any further, so efficacy is the first criterion for selection. Initially, you should look at groups of drugs rather than individual drugs. There are tens of thousands of different drugs, but only about 70 pharmacological groups! All drugs with the same working mechanism (dynamics) and a similar molecular structure belong to one group. As the active substances in a drug group have the same working mechanism, their effects, side effects, contraindications and interactions are also similar. The benzodiazepines, beta-blockers and penicillins are examples of drug groups. Most active substances in a group share a common stem in their generic name, such as diazepam, lorazepam and temazepam for benzodiazepines, and propranolol and atenolol for beta-blockers.

There are two ways to identify effective groups of drugs. The first is to look at formularies or guidelines that exist in your hospital or health system, or at international guidelines, such as the WHO treatment guidelines for certain common disease groups, or the WHO Model List of Essential Drugs. Another way is to check the index of a good pharmacology reference book and determine which groups are listed for your diagnosis or therapeutic objective. In most cases you will find only 2-4 groups of drugs which are effective. In Annex 2 various sources of information on drugs and therapeutics are listed.

Exercise

Look at a number of advertisements for new drugs. You will be surprised at how very few of these 'new' drugs are real innovations and belong to a drug group that is not already known.

to previous section
to next section
 
 
The WHO Essential Medicines and Health Products Information Portal was designed and is maintained by Human Info NGO. Last updated: June 25, 2014