(1993; 36 pages)
3.2. Infrared reference spectra
Further to the spectra established at the Committee’s previous meeting (3), it adopted 18 additional International Infrared Reference Spectra. Those listed in Annex 2 are now available from the WHO Collaborating Centre for Chemical Reference Substances, Stockholm, Sweden. Precise instructions for the preparation of spectra are provided with each reference spectrum. A separate document including recommendations for the preparation and use of infrared spectra in pharmaceutical analysis was provisionally adopted by the Committee subject to further consultation with the participating laboratories. Once finalized, the recommendations would accompany the reference spectra. It was noted that the general interchangeability of instruments had been confirmed during the validation exercise.
The Committee emphasized that the comparison of infrared spectra by means of either a reference spectrum or a reference substance required an appropriate level of expertise.