(2001; 179 pages)
Vaginal discharge may be caused by candidiasis (due to Candida albicans), trichomoniasis (due to Trichomonas vaginalis) or bacterial vaginosis (due to Gardnerella vaginalis and vaginal anaerobes).
Nystatin pessaries 200 000 IU inserted high into the vagina nightly for 2 weeks (in some geographical areas, nightly doses as high as 1 million IU may be required).
Administration should be continued for 48 hours after clinical cure. Higher doses and a longer period of treatment may be required in immunocompromised patients.
Metronidazole 2g orally in a single dose (sexual partners should be treated simultaneously; contraindicated during pregnancy).
Metronidazole 400 - 500 mg orally every 12 hours for 7 days (contraindicated during pregnancy).