WHO Pharmaceuticals Newsletter 2004, No. 01
(2004; 17 pages) View the PDF document
Table of Contents
Open this folder and view contentsREGULATORY MATTERS
Close this folderSAFETY OF MEDICINES
View the documentANTIEPILEPTICS - ADR update from Australia
View the documentBOTULINUM TOXIN TYPE A - Place in therapy not clearly defined
View the documentCELECOXIB/ROFECOXIB - Acute temporary visual impairment
View the documentDACLIZUMAB - Increased mortality in cardiac transplant patients
View the documentFLUTICASONE - Update on adrenal insufficiency reports
View the documentINTERFERON BETA - Safety information about risk of liver injury
View the documentMETHADONE - Risk of QT prolongation
View the documentMETHOTREXATE - Update on pulmonary effects
View the documentMIRTAZAPINE - ADR update from Australia
View the documentMORPHINE - Accidental overdose of concentrated oral solutions
View the documentNONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) - Postpartum administration may cause hypertension
View the documentPERGOLIDE - Danger of falling asleep during daily activities
View the documentPYRAZINAMIDE & RIFAMPICIN - Serious liver injury with combined use in latent tuberculosis
View the documentSIBUTRAMINE - ADR update
View the documentTOPIRAMATE - Warning about metabolic acidosis
View the documentWARFARIN - Interaction with cranberry juice
Open this folder and view contentsDRUGS OF CURRENT INTEREST
Open this folder and view contentsFEATURE
 

BOTULINUM TOXIN TYPE A - Place in therapy not clearly defined

Scotland. The Scottish Medicines Consortium (SMC) has completed its assessment of clostridium botulinum toxin type A (Botox) and have advised NHS Boards and Area Drug and Therapeutic Committees (ADTCs) that clostridium botulinum toxin A is not recommended for use within NHS Scotland for adult patients with focal spasticity of the wrist and hand that is associated with stroke. In their press statement the SMC state that clostridium botulinum toxin A produces a localised reduction in muscle tone in patients with post-stroke hand and wrist spasticity and may improve disability. However, the place in therapy was not clearly defined nor was the economic case proven.

Reference:

Scottish Medicines Consortium Press Statement, 17 November 2003. Available from URL: http://www.scottishmedicines.org

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Last updated: May 3, 2013