WHO Guidelines on Good Agricultural and Collection Practices (GACP) for Medicinal Plants
(2003; 80 pages) [French] [Spanish] View the PDF document
Table of Contents
View the documentAcknowledgements
View the documentForeword
Open this folder and view contents1. General introduction
Open this folder and view contents2. Good agricultural practices for medicinal plants
Open this folder and view contents3. Good collection practices for medicinal plants
Open this folder and view contents4. Common technical aspects of good agricultural practices for medicinal plants and good collection practices for medicinal plants
Open this folder and view contents5. Other relevant issues
View the documentBibliography
View the documentAnnex 1. Good Agricultural Practice for Traditional Chinese Medicinal Materials, People's Republic of China
Close this folderAnnex 2. Points to Consider on Good Agricultural and Collection Practice for Starting Materials of Herbal Origin
View the document1. Introduction
View the document2. General
View the document3. Quality assurance
View the document4. Personnel and education
View the document5. Building and facilities
View the document6. Equipment
View the document7. Documentation
View the document8. Seeds and propagation material
View the document9. Cultivation
View the document10. Collection
View the document11. Harvest
View the document12. Primary processing
View the document13. Packaging
View the document14. Storage and distribution
View the documentGlossary
View the documentAnnex 3. Good Agricultural and Collection Practices for Medicinal Plants (GACP), Japan
View the documentAnnex 4. A model structure for monographs on good agricultural practices for specific medicinal plants
View the documentAnnex 5. Sample record for cultivated medicinal plants
View the documentAnnex 6. Participants in the WHO Consultation on Good Agricultural and Field Collection Practices for Medicinal Plants
 

1. Introduction

Examples of adulteration of medicinal plants/herbal drugs with toxic herbal drugs demonstrate the need to establish good manufacturing practice for herbal starting materials. The concept of Good Manufacturing Practice for the manufacture, processing, packaging and storage of Active Pharmaceutical Ingredients (APIs) should thus also apply to medicinal plants/herbal drugs.

In the case of herbal drug preparations the production and primary processing of the medicinal plant/herbal drug has a direct influence on the quality of the API. Due to the inherent complexity of naturally grown medicinal plants/herbal drugs and the limited analytical techniques to characterise constituents solely by chemical or biological means, reproducible quality of starting materials of herbal origin requires an adequate quality assurance system for the collection and/or cultivation, harvest and primary processing.

Collection in wild habitats, often in developing countries, presents special problems, especially with regard to confusion with similar plants, environmental damage, lack of control and poorly qualified personnel.

The following "Points to Consider" on good agricultural and collection practice does not fall directly under GMP guidelines in the traditional sense. However, these considerations should be used as a basis for the establishment of such an appropriate quality assurance system.

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