As mentioned, certain elements of TRM may be protected under patents. There are, however, several aspects of patent systems that are likely to discourage, if not make impossible, their effective use by domestic companies in developing countries willing to commercialize TRM, as well as by healers or local/indigenous communities. Some such aspects may be tackled - though not necessarily solved - by introducing changes in patent laws and regulations, as described below. Adjustments in patent law and practice would also be required to curb misappropriation of TRM.