The Quality of Antimalarials - A Study in Selected African Countries - EDM Research Series No. 030
(2003; 67 pages) View the PDF document
Table of Contents
View the documentAuthors
View the documentCountry Research Team Leaders
View the documentLaboratory Support
View the documentAcknowledgements
View the documentAcronyms
View the documentExecutive summary
View the document1. Background
Open this folder and view contents2. Methodology
View the document3. Results
Close this folder4. Discussion
View the document4.1 Is there a problem?
View the document4.2 What is the magnitude of the problem?
View the document4.3 Is the problem limited to a particular distribution level?
View the document4.4 Is the problem limited to imported or domestic products?
View the document4.5 Limitations of the methodology
Open this folder and view contents5. Conclusions and recommendations
View the documentReferences
Open this folder and view contentsTables
Open this folder and view contentsAnnexes
View the documentOther documents in the EDM Research Series
View the documentEDM Research Series No. 30
 

4.3 Is the problem limited to a particular distribution level?

Analysis of the product failure rates by the level of the distribution chain (Table II) showed the highest failures for ingredient content of CQS at district medical stores (27.2%), followed by households (26.7%), vendor/shops (21%), pharmacies (14.2%), and health centres (11.1%). For CQT, the highest percentage ingredient content failures were recorded at the district hospital level (70.0%), followed by district medical stores (58.3%) and shops/vendors (50.0%). SPT had the highest percentage ingredient content failures at household level (30.7%). This may be linked to inadequate storage conditions in the homes. High SPT dissolution failures were found at all collection points, led by households (100%), health centres (85.7%), vendor/shops (73%), district hospitals (72.8%), district medical stores (72.2%) and pharmacies (69.8%), with teaching hospitals lowest (58.8%). The high failures in ingredient content found in CQS and SPT in Mozambique were collected at district hospitals and pharmacies. These products were imported into the country.

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