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The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances
(2003; 148 pages) View the PDF document
Table of Contents
View the documentPreface
View the documentAcknowledgements
View the documentReference to the volumes of the WHO Drug Information in which the respective proposed lists of INNs have been published:
View the documentLayout of information
View the documentPharmacological classification with corresponding examples of common stems and their definitions
View the documentAlphabetical list of stems together with corresponding INNs
View the documentAlphabetical list of common stems (INDEX PAGE)
View the documentANNEX 1: INNs for monoclonal antibodies
View the documentANNEX 2: Procedure for the selection of recommended international nonproprietary names for pharmaceutical substances*
View the documentANNEX 3: General principles for guidance in devising international nonproprietary names for pharmaceutical substances*
View the documentWhy INNs?
 

Alphabetical list of stems together with corresponding INNs

-abine

see -arabine, -citabine

 

USAN

-ac (x)

anti-inflammatory agents, ibufenac derivatives

A.4.2.0

(USAN: anti-inflammatory agents (acetic acid derivatives))

 

(a)

aceclofenac (52), alclofenac (23), amfenac (38), anirolac (52), bendazac (22), bromfenac (55), cinfenoac (41), clidanac (39), clofurac (42), clopirac (30), dexpemedolac (71), diclofenac (28), eltenac (53), etodolac (45), felbinac (54), fenclofenac (30), fenclorac (33), fentiazac (32), furofenac (40), ibufenac (14), isoxepac (37), ketorolac (51), lexofenac (38), nepafenac (78), oxepinac (36), oxindanac (54), pemedolac (58), (quinclorac, ISO name for a herbicide), sulindac (33), tianafac (31), tifurac (57), tiopinac (40), zomepirac (37)

 

-zolac: bufezolac (39), isofezolac (39), lonazolac (34), mofezolac (64), pirazolac (43), trifezolac (34)

(b)

amtolmetin guacil (65), bufexamac (20) (anti-inflammatory; acetohydroxamic acid group instead of acetic acid group)

(c)

clamidoxic acid (17), fenclozic acid (22), metiazinic acid (20), prodolic acid (29), tolmetin (23)

TRS 581

 

-acetam

see -racetam

 

USAN

-actide (x)

synthetic polypeptides with a corticotropin-like action

Q.1.1.1

(USAN: synthetic corticotropins)

(a)

alsactide (45), codactide (24), giractide (29), norleusactide (18), seractide (31), tetracosactide (18), tosactide (24), tricosactide (44)

TRS 581

 
 

BAN, USAN

-adol (x) or -adol-

analgesics (14th Report, 1967)

A.4.1.0

 

A.4.2/3.0

(USAN: analgesics (undefined group))

(a)

A.4.1.0: acetylmethadol (5), alimadol (39), alphacetylmethadol (5), alphamethadol (5), axomadol (87), betacetylmethadol (5), betamethadol (5), levacetylmethadol (27), noracymethadol (12), tapentadol (87)

 

A.4.2/3.0: apadoline (74), asimadoline (74), bromadoline (49), ciprefadol (41), ciramadol (39), cloracetadol (16), dibusadol (24), dimenoxadol (7), diproxadol (34), enadoline (68), filenadol (47), flumexadol (36), fluradoline (48), gaboxadol (48), levonantradol (43), lorcinadol (57), moxadolen (45), (deleted in List 48: moxifadol (47)), myfadol (17), nafoxadol (50), nantradol (42), nerbacadol (56), oxapadol (40), picenadol (47), pinadoline (50), pipradimadol (42), pipramadol (42), pravadoline (60), vadoline (60), profadol (20), radolmidine (82), ruzadolane (71), spiradoline (53), tazadolene (52), tolpadol (48), tramadol (22), veradoline (47)

(b)

alfadolone (27), hexapradol (12) (CNS stimulant), nadolol (34), quinestradol (15) (estrogenic)

(c)

A.4.1.0: dimepheptanol (5)

-adom

analgesics, tifluadom derivatives

A.4.3.0

(a)

lufuradom (50), tifluadom (48)

-afenone

antiarrhythmics, propafenone derivatives

H.2.0.0

(a)

alprafenone (62), berlafenone (63), diprafenone (48), etafenone (19), propafenone (29)

 

USAN

-aj-

antiarrhythmics, ajmaline derivatives

H.2.0.0

(a)

detajmium bitartrate (34), lorajmine (34), prajmalium bitartrate (23)

-al (d)

aldehydes

 

(deleted from General Principles in 14th Report)

 

USAN

-aldrate

antacids, aluminium salts

N.5.2.0

 

(a)

carbaldrate (53), potassium glucaldrate (14), sodium glucaspaldrate (17), magaldrate (49), simaldrate (15)

 

USAN

-alol

see -olol

-alox

see -ox

 

USAN

andr (d)

steroids, androgens

Q.2.3.0

(USAN: -andr- androgens)

(a)

i. andr: androstanolone (4), methandriol (1), nandrolone (22), norethandrolone (6), ovandrotone albumin (52), silandrone (18)

 

ii. -stan- (d): androstanolone (4), drostanolone (13), epitiostanol (31), mestanolone (10), stanozolol (18), epostane (51) (contraceptive)

 

iii. -ster- (d): calusterone (23), cloxotestosterone (12), fluoxymesterone (6), mesterolone (15), methyltestosterone (4), oxymesterone (12), penmesterol (14), prasterone (23), testosterone (4), testosterone ketolaurate (16), tiomesterone (14)

(b)

i. andr: oxandrolone (12), propetandrol (13)

 

iii. ster: aldosterone (6), bolasterone (13), dihydrotachysterol (1), dimethisterone (8), ethisterone (4), norethisterone (6), norvinisterone (6), stercuronium iodide (21) (neuromuscular blocking agent)

(c)

metandienone (12), oxymetholone (11), trestolone (25) (antineoplastic androgen)

TRS 581

 

-anide

 

-etanide

diuretics, piretanide derivatives

N.1.2.0

(USAN: diuretics (piretanide group))

 

(a)

bumetanide (24), piretanide (33)

(c)

besunide (30)

-oxanide

antiparasitic, salicylanilides and analogues

S.3.0.0

(a)

bromoxanide (31), clioxanide (19), rafoxanide (24)

 

thioanalogues: brotianide (24)

 

related: diloxanide (8), nitazoxanide (45)

(b)

closantel (36), flurantel (25), niclosamide (13), resorantel (23), salantel (29)

(c)

oxyclozanide (16)

other -anides:

aurothioglycanide (1) (anti-arthritic; gout-remedy), ceforanide (39) (antibiotic), oglufanide (86) (immunomodulator), polihexanide (24) (antibacterial), tiprostanide (48) (antihypertonic)

 

BAN, USAN

-anserin

serotonin receptor antagonists (mostly 5-HT2)

C.7.0.0

(USAN: serotonin receptor antagonists (undefined group))

(a)

adatanserin (70), altanserin (50), blonanserin (76), butanserin (51), eplivanserin (80), fananserin (69), flibanserin (75), ketanserin (46), lidanserin (62), pelanserin (57), seganserin (56), tropanserin (55)

(b)

serotonin receptor antagonists, psychoactive: cinanserin (17), glemanserin (68), mianserin (20), ritanserin (51)

 

USAN

-antel

anthelminthics (undefined group)

S.3.1.0

 

(a)

amidantel (40), carbantel (35), closantel (36), epsiprantel (57), febantel (38), flurantel (25), morantel (22), oxantel (31), pexantel (22), praziquantel (34), pyrantel (17), resorantel (23), salantel (29), zilantel (33), antelmycin (15)

TRS 581

 

-apine

see -pine

 

USAN

-(ar)abine

arabinofuranosyl derivatives

L.4.0.0/S.5.3.0

(USAN: -arabine: antineoplastic arabinofuranosyl derivatives)

 

(a)

ancitabine (36), capecitabine (73), cytarabine (14), decitabine (61), emtricitabine (80), enocitabine (46), fazarabine (56), fiacitabine (59), fludarabine (48), flurocitabine (38), galocitabine (65), gemcitabine (62), ibacitabine (57), nelarabine (80), vidarabine (23), zalcitabine (66)

(c)

S.5.3.0: ribavirin (31)

 

USAN

-arit

antiarthritic substances, acting like clobuzarit and lobenzarit, (mechanism different from anti-inflammatory type substances, e.g. -fenamates or -profens)

A.4.2.0

(USAN: antirheumatic substances, acting similarly to lobenzarit)

 

(a)

actarit (62), bindarit (64), clobuzarit (44), lobenzarit (46), romazarit (60)

 

USAN

-arol (d)

anticoagulants, dicoumarol derivatives

I.2.1.0

(USAN: anticoagulants (dicoumarol type))

 

(a)

acenocoumarol (6), clocoumarol (31), coumetarol (13), dicoumarol (23), tioclomarol (31), xylocoumarol (15)

(b)

cloridarol (29) (coron. vasodil.), fluindarol (16) (anticoag. of indonedione-type)

(c)

diarbarone (15), ethyl biscoumacetate (4), phenprocoumon (11), warfarin (23)

TRS 581

 

-arone

amiodarone (16) (anti-arrhythmic), benzarone (13), benzbromarone (13) (uricosuric), benziodarone (11), brinazarone (64) (calcium channel blocker), bucromarone (48) (antiarrhythmic), diarbarone (15), dronedarone (75) (anti-anginal, antiarrhythmic), etabenzarone (17), fantofarone (65) (calcium channel blocker), furidarone (19), inicarone (27), mecinarone (30), pyridarone (16), rilozarone (58)

arte-

antimalarial agents, artemisinin related compounds

S.3.3.0

(a)

artemether (61), artemisinin (56), artemotil (80), artenimol (81), artesunate (61), arteflene (70)

 

USAN

-ase

enzymes

W.0.0.0

 

(a)

agalsidase alfa (84), agalsidase beta (84), alglucerase (68), brinase (22), cocarboxylase (1), dornase alfa (70), eufauserase (84), hyalosidase (50), hyaluronidase (1), idusulfase (87), kallidinogenase (22), ocrase (28), pegaspargase (64), penicillinase (10), promelase (47), rizolipase (22), serrapeptase (31), sfericase (40), streptodornase (6), streptokinase (6), tilactase (50), urokinase (48)

(c)

batroxobin (29), bromelains (18), chymopapain (26), chymotrypsin (10), defibrotide (44), orgotein (31), sutilains (18), ubidecarenone (48)

Classification of enzymes

I

proteinase

   

(a)

with -ase suffix:

   
 

(INN)

(origin)

(use, action)

 

brinase (22)

Aspergillus oryzae

fibrinolytic

 

kallidinogenase (22)

pancreas or urine of mammals

splitting kinin, kallidin from kininogen (vasodilator)

 

ocrase (28)

Aspergillus ochraceus

fibrinolytic (topically: cleaning wounds)

 

pegaspargase (64)

 

asparaginase

 

promelase (46)

Aspergillus melleus

proteinase (chronic bronchitis)

 

rasburicase (81)

Aspergillus flavus

urate oxidase (hyperuricaemia)

 

serrapeptase (31)

Serratia sp. E15

proteinase (chronic paranasal sinusitis etc.)

 

sfericase (40)

Bacillus sphaericus

proteinase (chronic paranasal sinusitis etc.)

 

streptokinase (6)

Streptococcus haemolyticus

changing plasminogen into plasmine (activator of fibrinolysis)

 

urokinase (48)

human origin

plasminogen activator

 

urokinase alfa (27)

recombinant material

plasminogen activator

(b)

without -ase suffix:

   
 

batroxobin (29)

the venom of the serpent Bothopsatrox

thrombin like enzyme

 

bromelains (18)

Ananas comosus Merr.

fibrin depolymerizing (antiinflammatory)

 

chymopapain (26)

papaya late

proteolytic (chemonucleosis)

 

chymotrypsin (10)

mammalian pancreas

proteolytic (antiinflammatory, antioedema)

 

defibrotide (44)

mammalian pancreas

proteolytic (antiinflammatory, antioedema)

 

sutilains (18)

Bacillus subtilis

proteolytic

II

-lipase

   
 

rizolipase (22)

Rhizopus arrhizus var. Delemar

lipase

III

co-enzymes

   
 

cocarboxylase (1)

chemically defined

co-enzyme in the metabolism of pyruvic acid

 

ubidecarenone (48)

chemically defined

naturally occurring co-enzyme, a component in the electron transfer system in mitochondria (congestive heart failure)

 

USAN

IV

-dismase enzymes with superoxide dismutase activity

 

(USAN: superoxide dismutase activity (exception: orgotein))

(a)

ledismase (70), sudismase (58)

(c)

isomerase

 

orgotein (31)

mammalian tissue (liver, red blood cell etc.)

superoxide dismutase activity (anti-inflammatory)

 

pegorgotein (72)

V

-diplase plasminogen activator combined with another enzyme

 

amediplase (79)

 

USAN

VI

-teplase tissue-type-plasminogen activators

(a)

alteplase (59), anistreplase (59), desmoteplase (80), duteplase (62), lanoteplase (76), monteplase (71), nateplase (73), pamiteplase (78), reteplase (69), silteplase (65), tenecteplase (79)

 

USAN

VII

-uplase urokinase-type-plasminogen activators

(a)

nasaruplase (68), nasaruplase beta (85), saruplase (58)

VIII

others

 

agalsidase alfa (84)

human origin

treatment of deficiency of alpha-galactosidase activity (Fabry’s disease)

 

agalsidase beta (84)

hamster

treatment of deficiency of alpha- galactosidase activity (Fabry’s disease)

 

alfimeprase (85)

Agkistrodon contrix contrix

antithrombotic

 

dornase alfa (70)

human origin

treatment of cystic fibrosis

 

epafipase (85)

human origin

antiallergic, antiasthmatic

 

eufauserase (84)

Euphausia Superba

digests proteins and selected cell surface adhesion molecules (wound healing; viginal/oral candidosis)

 

hyalosidase (50)

 

hyaluronoglucosaminidase (treatment of myocardial infarction)

 

hyaluronidase (1)

various origins

depolymerizing hya luronic acid (cellular diffusion factor)

 

idusulfase (87)

 

treatment of Hunter Syndrome (Mucopolysaccharidosis Type II), degrades glycosaminoglycans heparan and dermatan sulfate

 

imiglucerase (72)

human origin (placenta isoenzyme)

 
 

laronidase (85)

human origin

 
 

penicillinase (10)

Bacillus cereus

inactivating penicillin

 

ranpirnase (81)

Rana pipiens

ribonuclease (antineoplastic)

 

streptodornase (6)

Streptococcus haemolyticus

hydrolysing desoxyribonucleoprotein

 

tilactase (50)

β-D-glactosidase

 
 

BAN, USAN

-ast (x)

antiasthmatic, antiallergics, not acting primarily as antihistaminics

   

K.0.0.0

(BAN: antiasthmatics, antiallergics when not acting primarily as antihistamines)

 

(USAN: antiasthmatics or antiallergic substances not acting primarily as antihistamines)

(a)

acitazanolast (72), acreozast (77), andolast (67), asobamast (63), ataquimast (82), bamaquimast, (76), batebulast (66), binizolast (60), bunaprolast (60), cilomilast (82), dametralast (54), dazoquinast (54), doqualast (48), eclazolast (55), eflumast (61), enofelast (67), enoxamast (52), fenprinast (48), filaminast (75), ibudilast (58), idenast (58), lirimilast (85), loxanast (46), melquinast (62), ontazolast (72), oxalinast (49), pemirolast (61), piclamilast (73), picumast (47), pirodomast (64), quazolast (55), raxofelast (68), repirinast (55), revenast (51), roflumilast (77), scopinast (76), suplatast tosilate (64), tazanolast (59), tetrazolast (67), tiacrilast (52), tibenelast (58), tioxamast (53), tiprinast (50), tofimilast (85), tranilast (46), zaprinast (46)

-lukast

leukotriene receptor antagonist

(a)

ablukast (61), cinalukast (70), iralukast (70), montelukast (73), pobilukast (70), pranlukast (67), ritolukast (64), sulukast (63), tomelukast (59), verlukast (65), zafirlukast (71)

-trodast

thromboxane A2 receptor antagonists, antiasthmatics

(a)

imitrodast (70), seratrodast (70)

(c)

bufrolin (34), oxarbazole (38), pirolate (44)

 

BAN, USAN

-astine (x)

antihistaminics

G.2.0.0

(BAN: antihistamines, not otherwise classifiable)

 

(USAN: antihistaminics (histamine-H1 receptor antagonists))

(a)

acrivastine (51), alinastine (74), azelastine (36), barmastine (59), bepiastine (19), bepotastine (78), bilastine (82), cabastinen (50), carebastine (52), clemastine (22), dorastine (23), ebastine (52), emedastine (59), epinastine (55), flezelastine (67), levocabastine (50), linetastine (74), mapinastine (72), mizolastine (64), moxastine (15), noberastine (59), octastine (37), perastine (15), piclopastine (22), rocastine (57), setastine (39), talastine (18), temelastine (54), zepastine (26)

(b)

cloperastine (18) (antitussive), vinblastine (12) (vinca-alkaloid)

(c)

astemizole (45), carbinoxamine (4)

-azam

see - azepam

 

USAN

-azenil

benzodiazepine receptor antagonists/agonists (benzodiazepine derivatives)

 

(a)

bretazenil (60), flumazenil (55), iomazenil 123I (66), sarmazenil (59)

(b)

nabazenil (49)

-carnil

benzodiazepine receptor antagonists/agonists (carboline derivatives)

 

(a)

abecarnil (60), gedocarnil (61)

-quinil

benzodiazepine receptor partial agonists (quinoline derivatives)

 

(a)

lirequinil (72), terbequinil (63)

   
 

BAN, USAN

-azepam (x)

diazepam derivatives

C.1.0.0

(BAN: substances of the diazepam group)

 

(USAN: antianxiety agents (diazepam type))

 

(a)

bromazepam (22), camazepam (30), carburazepam (39), cinolazepam (46), clonazepam (22), cyprazepam (16), delorazepam (40), diazepam (12), doxefazepam (43), elfazepam (36), fletazepam (31), fludiazepam (36), flunitrazepam (24), flurazepam (20), flutemazepam (58), flutoprazepam (45), fosazepam (27), halazepam (29), iclazepam (37), lorazepam (23), lormetazepam (38), meclonazepam (44), medazepam (20), menitrazepam (22), metaclazepam (46), motrazepam (31), nimetazepam (26), nitrazepam (16), nordazepam (39), nortetrazepam (20), oxazepam (13), pinazepam (32), pivoxazepam (34), prazepam (14), proflazepam (31), quazepam (36), reclazepam (53), sulazepam (14), temazepam (22), tetrazepam (17), tolufazepam (51), tuclazepam (40), uldazepam (30)

 

not true benzodiazepines: bentazepam (33), clotiazepam (30), lopirazepam (36), premazepam (45), ripazepam (33), zolazepam (28)

 

related: adinazolam (45), alprazolam (30), arfendazam (39), clazolam (29), climazolam (51), clobazam (25), clobenzepam (25), cloxazolam (29), ecopipam (80), estazolam (31), flutazolam (32), haloxazolam (38), ketazolam (26), lofendazam (36), loprazolam (44), mexazolam (40), midazolam (40), nefopam (25), oxazolam (25), razobazam (52), tofisopam (26), trepipam (38), triazolam (30), triflubazam (28), zapizolam (43), zomebazam (49)

(c)

brotizolam (40), chlordiazepoxide (11), ciclotizolam (40), demoxepam (23), dipotassium clorazepate (17), ethyl carfluzepate (43), ethyl dirazepate (44), ethyl loflazepate (43), etizolam (40), potassium nitrazepate (17)

TRS 581

not related: anti-anx.: fenobam (36), muscle relax.: xilobam (36)

-azepide

cholecystokinin receptor antagonist

J.1.0.0

 

(a)

devazepide (62), pranazepide (75), tarazepide (68)

(c)

lorglumide (56)

 

USAN

-azocine

narcotic antagonists/agonists related to 6,7-benzomorphan

A.4.1.0

(USAN: narcotic antagonists/agonists related to 6,7-benzo-morphan)

 

(a)

anazocine (30), bremazocine (43), butinazocine (53), carbazocine (16), cogazocine (36), cyclazocine (14), eptazocine (45), gemazocine (29), ibazocine (36), ketazocine (34), metazocine (9), moxazocine (38), pentazocine (14), phenazocine (9), quadazocine (54), tonazocine (46), volazocine (19)

(b)

streptozocin (33)

TRS 581

 

-azolam

see -azepam

 

USAN

-azoline

antihistaminics or local vasoconstrictors, antazoline derivatives

E.4.0.0

(USAN: antihistaminics or local vasoconstrictors of the antazoline group)

 

(a)

antazoline (1), cilutazoline (61), cirazoline (38), clonazoline (18), coumazoline (26), domazoline (30), fenoxazoline (12), indanazoline (42), metrafazoline (33), naphazoline (1), nemazo-line (63), oxymetazoline (13), phenamazoline (6), prednazoline (22), tefazoline (24), tinazoline (39), tramazoline (15), xylometazoline (8)

(b)

cefazolin (25) (antibiotic)

(c)

tetryzoline (6), metizoline (22)

TRS 581

 

-azone

see -buzone

 

USAN

-azosin

antihypertensive substances, prazosin derivatives

H.3.0.0

(USAN: antihypertensives (prazosin type))

 

(a)

bunazosin (50), doxazosin (47), neldazosin (60), prazosin (22), quinazosin (17), terazosin (44), tiodazosin (41), trimazosin (31)

 

related: alfuzosin (49), tamsulosin (65), tipentosin (55)

 

BAN, USAN

-bactam

β-lactamase inhibitors

S.6.5.0

 

(a)

brobactam (53), sulbactam (44), tazobactam (60)

(c)

clavulanic acid (44)

 

BAN, USAN

-bamate

tranquillizers, propanediol and pentanediol derivatives

C.1.0.0

(a)

cyclarbamate (13), meprobamate (6), nisobamate (21), pentabamate (13), tybamate (14)

(b)

difebarbamate (16), febarbamate (12), lorbamate (24), phenprobamate (10)

(c)

mebutamate (12), metaglycodol (12) (not a carbamate)

TRS 581

 
 

BAN, USAN

barb (d)

hypnotics, barbituric acid derivatives

A.2.1.0

(BAN: -barb, -barb-: for barbiturates)

 

(USAN: -barb; or -barb-: barbituric acid derivatives)

 

(a)

allobarbital (1), amobarbital (1), aprobarbital (1), barbexa-clone (16), barbital (4), barbital sodium (4), benzobarbital (25), brallobarbital (41), carbubarb (14), cyclobarbital (1), difebarbamate (16), eterobarb (32), febarbamate (12), heptabarb (14), hexobarbital (1), methylphenobarbital (1), nealbarbital (11), pentobarbital (1), phenobarbital (4), phenobarbital sodium (4), probarbital sodium (1), proxibarbal (33), secbutabarbital (12), secobarbital (4), tetrabarbital (4), thialbarbital (4), thiotetrabarbital (4), vinbarbital (1)

(c)

butalbital (4), buthalital sodium (8), metharbital (1), methitural (6), methohexital (8), phetharbital (10), talbutal (17), thiopental sodium (4), vinylbital (12) prazitone (19) (barbituric acid derivative used as antidepressive), bucolome (17) (barbituric acid derivative used as anti-inflammatory uricosuric)

TRS 581

 

-bendan

see -dan

 

USAN

-bendazole

anthelminthics, tiabendazole derivatives

S.3.1.0

(USAN: anthelmintics (tiabendazole type))

 

(a)

albendazole (35), albendazole oxide (56), bisbendazole (29), cambendazole (24), ciclobendazole (31), dribendazole (49), etibendazole (49), fenbendazole (29), flubendazole (34), lobendazole (28), luxabendazole (52), mebendazole (24), oxibendazole (30), parbendazole (19), subendazole (31), tiabendazole (13), triclabendazole (45)

(b)

bendazol (12) (vasodilator, also benzimidazole derivative)

 

L.0.0.0: nocodazole (36), procodazole (36) (also benzimidazole derivative)

c)

oxfendazole (35), tioxidazole (39)

 

related: furodazole (37) (S.3.1.0)

TRS 581

 
 

BAN, USAN

bol (x)

anabolic steroids

M.4.1.0

(BAN: steroids, anabolic)

 

(USAN: bol- or -bol-: anabolic steroids)

(a)

bolandiol (16), bolasterone (13), bolazine (21), boldenone (20), bolenol (19), bolmantalate (16), clostebol (22), enestebol (22), formebolone (31), furazabol (16), mebolazine (21), mesabolone (29), metribolone (17), mibolerone (27), norboletone (15), norclostebol (22), oxabolone cipionate (14), quinbolone (14), roxibolone (40), stenbolone (17), tibolone (22), trenbolone (24)

(c)

ethylestrenol (13), hydroxystenozole (10), metandienone (12), metenolone (12), oxandrolone (12), propetandrol (13), tiomesterone (14)

 

-bradine

bradycardic agents

H.0.0.0

 

(a)

cilobradine (63), ivabradine (75), zatebradine (62)

-brate

see -fibrate

 

USAN

-buzome (x)

anti-inflammatory analgesics, phenylbutazone derivatives

A.4.2.0

(a)

feclobuzone (27), kebuzone (19), pipebuzone (25), suxibuzone (24), tribuzone (33)

-butazone

(USAN: anti-inflammatory analgesics of the phenylbutazone type)

 

mofebutazone (15), oxyphenbutazone (8), phenylbutazone (1)

-azone

aminophenazone (13), bisfenazone (33), famprofazone (21), morazone (12), nifenazone (15), nimazone (20), niprofazone (29), phenazone (4), propyphenazone (1), sulfinpyrazone (8)

-zone

clofezone (17), proxifezone (24)

related:

azapropazone (18), benhepazone (15), bumadizone (24), cinnopentazone (17), isamfazone (37), metamfazone (12), osmadizone (26), ruvazone (26)

(c)

benzpiperylone (12), butopyrammonium iodide (8), dibupyrone (17), metamizole sodium (53), metazamide (16), piperylone (11)

TRS 581

 
 

BAN, USAN

-caine (x)

local anaesthetics

D.1.0.0

 

(a)

ambucaine (6), amoxecaine (1), aptocaine (21), articaine (47) (previously carticaine (27)), benzocaine (42), betoxycaine (13), bucricaine (49), bumecaine (25), bupivacaine (17), butacaine (4), butanilicaine (16), chloroprocaine (6), cinchocaine (1), clibucaine (14), clodacaine (13), clormecaine (17), cyclomethycaine (6), dexivacaine (20), diamocaine (22), edronocaine (84), elucaine (29), etidocaine (29), fexicaine (25), fomocaine (18), hexylcaine (4), hydroxyprocaine (1), hydroxytetracaine (1), ipravacaine (85), ketocaine (15), leucinocaine (17), levobupivacaine (74), lidocaine (1), lotucaine (27), mepivacaine (11), meprylcaine (4), myrtecaine (15), octacaine (14), oxetacaine (13), oxybuprocaine (8), parethoxycaine (1), paridocaine (8), phenacaine (4), pinolcaine (32), piperocaine (1), piridocaine (1), pramocaine (4), pribecaine (32), prilocaine (14), procaine (10), propanocaine (6), propipocaine (16), propoxycaine (4) proxymetacaine (6), pyrrocaine (13), quatacaine (18), quinisocaine (4), risocaine (26), rodocaine (27), ropivacaine (50), tetracaine (4), tolycaine (16), trapencaine (56), trimecaine (11), vadocaine (57)

(c)

amolanone (6), benzyl alcohol (1), cryofluorane (6), diperodon (1), dyclonine (6), midamaline (6)

         
 

BAN

-cain- (x)

Class I antiarrhythmics, procainamide and lidocaine derivatives

H.2.0.0

(BAN: antifibrillants with local anaesthetic activity)

 

(a)

acecainide (39), asocainol (47), barucainide (52), bucainide (35), carcainium chloride (36), carocainide (46), droxicainide (47), encainide (40), epicainide (40), erocainide (50), flecainide (37), guafecainol (38), indecainide (48) (originally ricainide (47)), itrocainide (54), ketocainol (32), lorcainide (38), milacainide (77), modecainide (63), murocainide (46), nicainoprol (46), nofecainide (44), pilsicainide (62), pincainide (49), procainamide (1), quinacainol (50), recainam (54), solpecainol (55), stirocainide (47), suricainide (55), tocainide (36), transcainide (51), (verocainine (42) - replaced by tiapamil in List 43), zocainone (41)

         
 

USAN

calci

Vitamin D analogues/derivatives

N.8.0.0

(a)

alfacalcidol (40), calcifediol (26), calcipotriol (61), calcitriol (39), colecalciferol (13), doxercalciferol (82), ecalcidene (85), ergocalciferol (13), falecalcitriol (74), inecalcitol (87), lexacalcitol (71), maxacalcitol (75), paricalcitol (78), secalciferol (62), seocalcitol (78), tacalcitol (65)

(b)

calcitonin (31) (polypeptide)

(c)

dihydrotachysterol (1)

 

USAN

-carbef

antibiotics, carbacepham derivatives

S.6.1.0

 

(a)

loracarbef (60)

-carnil

see -azenil

 

BAN, USAN

cef- (x)

antibiotics, cefalosporanic acid derivatives

S.6.1.0

(USAN: cephalosporins)

 

(a)

cefacetrile (25), cefaclor (36), cefadroxil (33), cefalexin (18), cefaloglycin (16), cefalonium (16), cefaloram (16), cefaloridine (15), cefalotin (14), cefamandole (30), cefaparole (33), cefapirin (23), cefatrizine (34), cefazaflur (36), cefazedone (36), cefazolin (25), cefbuperazone (48), cefcanel (59), cefcanel daloxate (59), cefcapene (68), cefclidine (64), cefdaloxime (64), cefdinir (61), cefditoren (66), cefedrolor (53), cefempidone (58), cefepime (57), cefetamet (49), cefetecol (64), cefetrizole (44), cefivitril (52), cefixime (53), cefizopran (66), cefluprenam (71), cefmatilen (81), cefmenoxime (44), cefmepidium chloride (57), cefmetazole (39), cefminox (53), cefodizime (44), cefonicid (42), cefoperazone (42), ceforanide (39), cefoselis (71), cefotaxime (40), cefotetan (48), cefotiam (40), cefoxazole (34), cefoxitin (29), cefozopran (66), cefpimizole (50), cefpiramide (47), cefpirome (50), cefpodoxime (58), cefprozil (60), cefquinome (59), cefradine (26), cefrotil (34), cefroxadine (42), cefsulodin (38), cefsumide (38), ceftazidime (44), cefteram (55), ceftezole (34), ceftibuten (60), ceftiofur (53), ceftiolene (49), ceftioxide (43), ceftizoxime (42), ceftizoxime alaproxil (77), ceftriaxone (44), cefuracetime (45), cefuroxime (34), cefuzonam (55)

TRS 581

 

-oxef

antibiotics, oxacefalosporanic acid derivatives

       

S.6.1.0

(USAN: antibiotic oxacefalosporanic acid derivatives)

 

(a)

flomoxef (55), latamoxef (46)

cell- or

cellulose derivatives

cel-

[cel- in spanish]

U.4.0.0

 

(a)

celucloral (40)

(c)

celiprolol (35)

cell-ate

cellulose ester derivatives for substances containing acidic residues

U.4.0.0

[cel-ato in spanish]

(a)

cellaburate (23), cellacefate (18)

-cellose

cellulose ether derivatives

U.4.0.0

[-elosa in spanish]

(a)

-

(c)

carmellose (45), croscarmellose (48), ethylcellulose (80), hyetellose (80), hymetellose (80), hyprolose (80), hypromellose (18), methylcellulose (4)

 

USAN

-cic

hepatoprotective substances with a carboxylic acid group

J.1.2.0

(USAN: hepatoprotectives (timonacic group))

(a)

limazocic (69), tidiacic (33), timonacic (33), (tiofacic (45) replaced by stepronin (46))

(b)

bisorcic (34) (psychostimulant)

(c)

stepronin (46)

 

USAN

-cidin

naturally occurring antibiotics (undefined group) (14th Report, 1964)

S.6.0.0

(USAN: natural antibiotics (undefined group))

(a)

candicidin (17), gramicidin (1), gramicidin S (26), methocidin (6)

(b)

guancidine (18) (hypotensive)

 

BAN, USAN

-cillin (x)

antibiotics, 6-aminopenicillanic acid derivatives

S.6.1.0

(USAN: penicillins)

 

(a)

adicillin (14), almecillin (14), amantocillin (17), amoxicillin (27), ampicillin (13), apalcillin (39), aspoxicillin (50), azidocillin (19), azlocillin (36), bacampicillin (32), benethamine penicillin (1), benzathine benzylpenicillin (18), benzylpenicillin (53), carbenicillin (20), carfecillin (30), carindacillin (29), ciclacillin (22), clemizole penicillin (8), clometocillin (12), cloxacillin (13), dicloxacillin (16), epicillin (25), fenbenicillin (13), fibracillin (30), flucloxacillin (17), fomidacillin (55), fumoxicillin (47), furbucillin (31), fuzlocillin (47), hetacillin (16), isopropicillin (12), lenampicillin (50), levopropicillin (12), metampicillin (20), meticillin (12), mezlocillin (34), nafcillin (13), oxacillin (15), oxetacillin (33), penamecillin (16), pheneticillin (11), phenoxymethyl penicillin (6), phenyracillin (8), piperacillin (38), pirbenicillin (35), piridicillin (43), piroxicillin (49), pivampicillin (23), prazocillin (27), propicillin (13), quinacillin (14), rotamicillin (35), sarmoxicillin (41), sarpicillin (36), sulbenicillin (26), sultamicillin (48), suncillin (25), talampicillin (31), tameticillin (35), temocillin (46), ticarcillin (29), tifencillin (12), tobicillin (78)

(b)

xantocillin (12)

(c)

penimepicycline (16), penimocycline (22)

-cillide:

 

S.6.1.0

libecillide (32)

-cillinam:

 

S.6.1.0

bacmecillinam (38), mecillinam (32), pivmecillinam (32)

TRS 581

 

-cisteine

see -steine

 

USAN

-citabine

nucleoside antiviral or antineoplastic agents, cytarabine or azarabine derivatives

L.4.0.0

(a)

ancitabine (36), capecitabine (72), decitabine (61), enocitabine (46), fiacitabine (59), flurocitabine (38), galocitabine (65), gemcitabine (62), ibacitabine (57), tezacitabine (84), torcitabine (87), troxacitabine (81), zalcitabine (66)

(b)

cytarabine (14), azacitidine (40)

-clone

hypnotic tranquillizers

A.2.2.0

 

(a)

barbexaclone (16), eszopiclone (87), pagoclone (74), pazinaclone (70), suproclone (46), suriclone (43), suproclone (46), zopiclone (39)

(b)

gestaclone (23), pimeclone (20)

-cog

blood coagulation factors

I.2.0.0

 

(-)eptacog blood coagulation VII:

eptacog alfa (activated) (72)

(-)octocog blood factor VIII:

moroctocog alfa (72), octocog alfa (73)

(-)nonacog blood factor IX:

nonacog alfa (77)

 

related: drotrecogin alfa (85), tifacogin (78)

 

BAN, USAN

-conazole (x)

systemic anifungal agents, miconazole derivatives

S.4.0.0

(BAN: systemic antifungals of the miconazole group)

 

(USAN: systemic antifungals (miconazole type))

 

(a)

albaconazole (87), aliconazole (43), alteconazole (53), azaconazole (45), becliconazole (65), brolaconazole (58), butoconazole (40), cisconazole (59), croconazole (55), (cyproconazole (ISO)), democonazole (42), (diniconazole (ISO C17H17Cl2N3O)), doconazole (37), eberconazole (64), econazole (27), enilconazole (44), ((etaconazole (ISO)), fenticonazole (44), fluconazole (54), fosfluconazole (83), ((furconazole (ISO/TC 81 N 872 C15H14Cl2F3N3O2)), (hexaconazole (ISO C14H17Cl2N3O)), isoconazole (30), itraconazole (50), ketoconazole (43), lanoconazole (66), luliconazole (86), miconazole (22), neticonazole (63), omoconazole (45), orconazole (40), oxiconazole (42), parconazole (39), (penconazole, (ISO)), posaconazole (82), (propiconazole (ISO)), ravuconazole (83), saperconazole (59), sertaconazole (56), sulconazole (38), (tebuconazole (ISO C16H22CIN3O)), terconazole (45) (originally triaconazole), tioconazole (40), (uniconazole (ISO C15H18ClN3O)), valconazole (40), voriconazole (73), zinoconazole (50), zoficonazole (43)

(c)

bifonazole (44)

 

BAN, USAN

cort (x)

corticosteroids, except prednisolone derivatives

Q.3.0.0

(USAN: -cort-: cortisone derivatives)

 

(a)

amebucort (54), anecortave (80), butixocort (63), cicortonide (28), corticotropin (68), corticotropin-zinc hydroxide (68), cortisone (1), cortisuzol (30), cortivazol (23), cortodoxone (15), deflazacort (39) (previously azacort (38)), desoxycortone (4), fluazacort (30), fludrocortisone (6), fludroxycortide (12), fluocortin (31), formocortal (18), hydrocortamate (6), hydrocortisone (1), locicortolone dicibate (60), naflocort (50), nicocortonide (40), nivacortol (24), resocortol (74), tixocortol (38)

(b)

prednisolone derivatives: clocortolone (16), difluocortolone (18), fluocortolone (15), halocortolone (31)

(c)

aldosterone (6), algestone (22) (also progest. when used as algestone acetophenide), medrysone (16)

TRS 581

 
 

USAN

-crinat

diuretics, etacrynic acid derivatives

N.1.2.2

(USAN: diuretics (ethacrynic acid derivatives))

 

(a)

brocrinat (51), sulicrinat (52)

(c)

etacrynic acid (14), furacrinic acid (29), indacrinone (51), tienilic acid (25)

 

USAN

-crine (d)

acridine derivatives

 

(a)

antineoplastics: amsacrine (44), nitracrine (35)

 

anthelminthics; antimalarials: floxacrine (34), mepacrine (4)

 

antidepressants: dimetacrine (19), monometacrine (19)

 

antiparkinsonian: botiacrine (38)

 

acetylcholinesterase inhibitors: ipidacrine (73), suronacrine (61), tacrine (8), velnacrine (61)

(c)

acridorex (21), acriflavinium chloride (1), acrisorcin (13), aminoacridine (1), ethacridine (1), proflavine (1)

 

USAN

-cromil

antiallergics, cromoglicic acid derivatives

K.0.0.0

(USAN: antiallergics (cromoglicic acid type))

   
 

   

(a)

ambicromil (48) (replacement of probicromil (46)), isocromil (39), minocromil (50), nedocromil (50), proxicromil (39), terbucromil (38), texacromil (58)

(c)

cromitrile (46), cromoglicate lisetil (72), cromoglicic acid (18)

-curium

see -ium

 

BAN, USAN

-cycline (d)

antibiotics, tetracycline derivatives

S.6.3.0

(BAN: antibiotics of the tetracycline group)

 

(USAN: antibiotics tetracycline derivatives)

 

(a)

amicycline (14), apicycline (17), cetocycline (39), chlortetracycline (4), clomocycline (16), colimecycline (33), demeclocycline (25), demecycline (14), doxycycline (16), etamocycline (18), guamecycline (22), lymecycline (14), meclocycline (14), meglucycline (22), metacycline (12), minocycline (14), nitrocycline (14), oxytetracycline (1), pecocycline (15), penimepicycline (16), penimocycline (22), pipacycline (12), rolitetracycline (11), sancycline (15), tetracycline (4), tigecycline (86)

 

related: carubicin (40), daunorubicin (20), detorubicin (41), doxorubicin (25), zorubicin (39)

TRS 581

 
 

USAN

-dan

cardiac stimulants, pimobendan derivatives

H.1.0.0

(a)

adibendan (57), bemorodan (61), imazodan (55), indolidan (57), levosimendan (68), meribendan (62), pimobendan (46), prinoxodan (64), senazodan (85), simendan (66)

(b)

nitrodan (15), tyromedan (15)

 

USAN

-dapsone

antimycobacterials, diaminodiphenylsulfone derivatives (14th Report, 1964)

S.5.2.0

(USAN: antimycobacterial diaminodiphenylsulfone derivatives)

 

(a)

acedapsone (22), amidapsone (28), dapsone (23)

-dermin

see -ermin

 

USAN

-dil

vasodilators (18th Report, 1968)

F.2.0.0

 

F.2.1./2.0

(USAN: -dil; dil-; or -dil-: vasodilators (undefined group))

F.2.0.0

 

(a)

alprostadil (39), aviptadil (78), belfosdil (61), benfurodil hemisuccinate (16), biclodil (52), buflomedil (33), burodiline (26), carprazidil (45), cetiedil (27), cinepaxadil (50), dopropidil (59), eliprodil (66), fenoxedil (27), flosatidil (64), fostedil (51), fronepidil (59), ifenprodil (27), levosemotiadil (72), manozodil (47), mefenidil (48), minoxidil (25), naftopidil (52), naminidil (87), nesapidil (52), perfomedil (60), pinacidil (46), piribedil (23), pitenodil (37), podilfen (22), stevaladil (34), suloctidil (30), tipropidil (44), urapidil (27), viquidil (25)

(c)

dilmefone (33)

F.2.1.0

 

(a)

coronary vasodilators: bepridil (30), bumepidil (44), ecipramidil (40), fendiline (24), fenetradil (30), floredil (28), hexadiline (13), ipramidil (51), mepramidil (27), metrifudil (23), nicorandil (44), pirozadil (33), pretiadil (27), razi-nodil (38), semotiadil (64), sinitrodil (74), terodiline (16), tixadil (18), trapidil (29)

(c)

dilazep (22), diltiazem (30)

-dilol

carvedilol (50), dioxadilol (53), dramedilol (57), flavodilol (48), mindodilol (52), nipradilol (50) (previously nipradolol), oberadilol (77), parodilol (57), prizidilol (44), tribendilol (54)

(b)

diloxanide (8) (amebicide), methdilazine (10) (antihistaminic), phenobutiodil (6) (contrast medium), prodilidine (12) (analgesic)

-pendyl

cloxypendyl (15), isothipendyl (6), oxypendyl (13), prothipendyl (6)

-dyl

bisacodyl (13) (lax.), bunamiodyl (10), iofendylate (12), trihexyphenidyl (1) (antiparksonian)

TRS 581

 
 

BAN, USAN

-dipine (x)

calcium channel blockers, nifedipine derivatives

F.2.1.0

(BAN: calcium ion channel antagonists)

 

(USAN: phenylpyridine vasodilators (nifedipine type))

 

(a)

amlodipine (53), aranidipine (69), azelnidipine (69), barnidipine (64), benidipine (58), cilnidipine (66), clevidipine (75), cronidipine (61), darodipine (51) (replaces dazodipine (49)), efonidipine (66), elgodipine (61), felodipine (44), flordipine (48), furnidipine (67), iganidipine (70), isradipine (55), lacidipine (57), lemildipine (69), lercanidipine (69) (previously masnidipine), levniguldipine (67), manidipine (59), mesudipine (40), nicardipine (42), nifedipine (27), niguldipine (60), niludipine (38), nilvadipine (52), nimodipine (40), nisoldipine (42), nitrendipine (42), olradipine (69), oxodipine (52), palonidipine (64), pranidipine (66), riodipine (51), sagandipine (64), sornidipine (58), teludipine (64) (previously taludipine (61))

(b)

budipine (36) (central stimulant, antidepressant and antiparkinsonian), prodipine (29) (central stimulant antiparkinsonian)

-dismase

enzymes with superoxide dismutase activity, see -ase item V

-dopa

dopamine receptor agonists, dopamine derivatives, used as antiparkinsonism/prolactin inhibitors

E.1.1.0

(a)

carbidopa (37), ciladopa (52), dopamantine (31), droxidopa (57), etilevodopa (80), fluorodopa (18F) (64), levodopa (21), melevodopa (83)

-opamine

dopaminergic agents dopamine derivatives used as cardiac stimulant/antihypertensives/diuretics

(a)

butopamine (43), cliropamine (59), denopamine (50), dopamine (18), fosopamine (69), ibopamine (43), octopamine (32), oxidopamine (37) (glaucoma), ractopamine (54) (1 of 4 isomers of butopamine)

(b)

tiopropamine (36) (gastric and duodenal ulcers), tolpropamine (13) (antihistaminic)

(c)

dobutamine (29), docarpamine (59), dopexamine (50), fenoldopam (53), levdobutamine (65), methyldopa (12) (alpha-2 adrenoreceptor agonist, cardiotonic), zelandopam (84)

 

USAN

-dralazine

antihypertensives, hydrazinephthalazine derivatives

H.3.0.0

(USAN: antihypertensives (hydrazine-phthalazines))

 

(a)

budralazine (33), cadralazine (41), dihydralazine (4), endralazine (39), hydralazine (1), mopidralazine (52), oxdralazine (38), picodralazine (18), pildralazine (48), todralazine (26)

-drine

sympathomimetics (16th Report, 1966)

E.4.0.0

 

(a)

alifedrine (49), butidrine (16), cafedrine (14), cinnamedrine (19), corbadrine (1), dioxethedrin (6), dioxifedrine (41), etafedrine (14), meluadrine (78), methoxyphedrine (6), midodrine (27), norbudrine (17), oxyfedrine (16), pholedrine (1), pseudoephedrine (11), racephedrine (66), ritodrine (22), theophylline ephedrine (14), tinofedrine (32), trecadrine (53)

 

not phenethylamine derivatives: levopropylhexedrine (37), octodrine (19), propylhexedrine (6)

(b)

bufenadrine (13) (antiemetic) related chemically, chlormerodrin (4) (diuretic), chlormerodrin (197 Hg) (24), dieldrin (10) (insecticide), orphenadrine (8) (spasmolytic)

TRS 581

 

-frine

sympathomimetic, phenethyl derivatives

E.4.0.0

(a)

amidefrine mesilate (15), berefrine (68), ciclafrine (33), dimetofrine (27), dipivefrine (39), epinephrine (16), etilefrine (18), etilefrine pivalate (50), gepefrine (38), norepinephrine (45), norfenefrine (16), oxilofrine (62), phenylephrine (1), pivenfrine (42), racepinefrine (41)

 

USAN

-dronic acid

calcium metabolism regulator, pharmaceutical aid

N.8.0.0

 

U.4.0.0

(USAN: -dronate: calcium metabolism regulators)

(a)

alendronic acid (61), butedronic acid (59), clodronic acid (37), etidronic acid (22), ibandronic acid (71), incadronic acid (70), lidadronic acid (84), medronic acid (39), minodronic acid (78), neridronic acid (61), olpadronic acid (71), oxidronic acid (42), pamidronic acid (59), piridronic acid (58), risedronic acid (62), tiludronic acid (60), zoledronic acid (71)

 

USAN

-ectin

antiparasitics, ivermectin derivatives

S.3.0.0

(a)

abamectin (53), dimadectin (73), doramectin (63), eprinomectin (73), fuladectin (71), ivermectin (44), moxidectin (61), nemadectin (60), selamectin (81)

 

USAN

-entan

endothelin receptor antagonists

F.2.0.0

 

(a)

ambrisentan (85), atrasentan (83), bosentan (70), darusentan (82), edonentan (86), enrasentan (80), fandosentan (87), feloprentan (85), sitaxentan (83), tezosentan (81)

 

USAN

erg

ergot alkaloid derivatives

F.4.0.0

 

C.7.0.0

(USAN: -erg-: ergot alkaloid derivatives)

(a)

acetergamine (18), amesergide (67), brazergoline (37), bromerguride (51), cabergoline (54), cianergoline (47), delergotrile (42), dihydroergotamine (16), disulergine (45), dosergoside (54), ergometrine (4), ergotamine (4), etisulergine (47), lergotrile (32), lysergide (8), mergocriptine (54), mesulergine (47), metergoline (18), metergotamine (29), methylergometrine (1), methysergide (11), nicergoline (26), pergolide (41), propisergide (35), proterguride (50), romergoline (66), sergolexole (60), terguride (50), tiomergine (42), voxergolide (61)

(b)

ergocalciferol (13)

 

USAN

-eridine

analgesics, pethidine derivatives (14th Report, 1964)

A.4.1.0

(USAN: analgesics (meperidine group))

 

(a)

anileridine (5), carperidine (11), etoxeridine (6), morpheridine (6), oxpheneridine (5), pheneridine (5), phenoperidine (11), properidine (5), sameridine (68), trimeperidine (6)

(b)

diaveridine (18) (coccidiostat.), eseridine (53), nexeridine (34) (somewhat related)

(c)

benzethidine (9), butoxylate (14), diphenoxylate (10), fetoxilate (21), furethidine (9), hydroxypethidine (5), pethidine (4), piminodine (9)

 

USAN

-ermin

growth factors

U.0.0.0

(USAN: growth factors)

-bermin

vascular endothelial growth factors

(a)

telbermin (85)

-dermin

epidermal growth factors

(a)

murodermin (63)

-fermin

fibrinoblast growth factors

(a)

ersofermin (66), palifermin (86), repifermin (82), trafermin (74)

-filermin

leukemia-inhibiting factor

(a)

emfilermin (82)

-nermin

tumour necrosis factor

(a)

plusonermin (73), sonermin (68), tasonermin (76)

-plermin

platelet-derived growth factor

(a)

becaplermin (74)

-sermin

insulin-like growth factors

(a)

mecasermin (66)

-termin

transforming growth factor

 

avotermin (77), cetermin (74), liatermin (81)

 

BAN, USAN

estr

estrogens

Q.2.1.0

(USAN: estr-; or -estr-: estrogens)

(a)

almestrone (24), benzestrol (1), broparestrol (8), cloxestradiol (12), dienestrol (1), diethylstilbestrol (4), epiestriol (12), epimestrol (22), (eptamestrol/etamestrol (49) deleted), estradiol (4), estradiol benzoate (4), estradiol undecylate (16), estradiol valerate (35), estramustine (24), estrapronicate (34), estrazinol (16), estriol succinate (14), estrofurate (25), estrone (4), ethinylestradiol (1), fenestrel (18), fosfestrol (15), fulvestrant (78), furostilbestrol (1), hexestrol (1), mestranol (12), methallenestril (6), methestrol (1), moxestrol (24), nilestriol (32), orestrate (17), polyestradiol phosphate (36), promestriene (31), quinestradol (15), quinestrol (14)

(b)

alfatradiol (84) (topical), allylestrenol (10) (progest.), ethylestrenol (13) (anabol.), lynestrenol (13) (progest.)

-gestr-:

edogestrone (22), levonorgestrel (30), megestrol (13), melengestrol (13), norgestrel (17), norgestrienone (18), pentagestrone (14), quingestrone (13)

(c)

chlorotrianisene (6), clomifene (12), enclomifene (33), zuclomifene (33) (antiestrogens)

TRS 581

 

-etanide

see -anide

-ethidine

see -eridine

-exine

mucolytic, bromhexine derivatives

K.0.0.0

(a)

adamexine (36), bromhexine (20), brovanexine (31), cistinexine (54), dembrexine (56), neltenexine (62), oxabrexine (40)

(b)

enefexine (54) (antidepressant), gamfexine (17) (antidepressant)

(c)

ambroxol (32) (dembrexol (50): replaced by dembrexine (56))

 

USAN

-fenamic acid

anti-inflammatory, anthranilic acid derivatives

-fenamate

"fenamic acid" derivatives

A.4.2.0

(a)

clofenamic acid (13), enfenamic acid (45), flufenamic acid (13), meclofenamic acid (17), mefenamic acid (13), tolfenamic acid (24) colfenamate (29), etofenamate (29), prefenamate (36), terofenamate (32), ufenamate (50)

(b)

clantifen (24), oxyfenamate (13)

 

phonetically close: clofenamide (13), diclofenamide (13) (N.1.1.0)

(c)

flutiazin (22)

 

USAN

-fenine

analgesics, glafenine derivatives (subgroup of fenamic acid group)

phenine

 

A.4.3.0

(a)

antrafenine (35), floctafenine (24), florifenine (50), glafenine (15), nicafenine (40)

(b)

spasmolytic diphenylacetates: adiphenine (1), drofenine (26)

 

other: bufenine (8) (vasodil.), cinfenine (27) (antidepressant)

 

USAN

-fenin

diagnostic aids; (phenylcarbamoyl)methyl iminodiacetic acid derivatives

U.1.0.0

(a)

arclofenin (52), butilfenin (41), disofenin (43), etifenin (43), galtifenin (59), lidofenin (39), mebrofenin (47)

 

USAN

-fentanil

narcotic analgesics, fentanyl derivatives

A.4.1.0

(a)

alfentanil (43), brifentanil (62), carfentanil (39), fentanyl (14), lofentanil (43), mirfentanil (64), ocfentanil (61), remifentanil (67), sufentanil (36), trefentanil (67)

-fiban

fibrinogen receptor antagonists (glycoprotein IIb/IIIa receptor antagnists)

I.2.0.0

 
 

carafiban (78), elarofiban (83), fradafiban (72), gantofiban (80), lamifiban (72), lefradafiban (75), lotrafiban (78), orbofiban (75), roxifiban (77), sibrafiban (77), tirofiban (73), xemilofiban (74)

 

BAN, USAN

-fibrate (x)

clofibrate derivatives

H.4.0.0

(BAN: substances of the clofibrate group)

 

(USAN: clofibrate type compounds)

 

(a)

bezafibrate (35), biclofibrate (28), binifibrate (44), ciprofibrate (36), clinofibrate (39), dulofibrate (43), etofibrate (31), fenirofibrate (49), fenofibrate (35), lifibrate (30), nicofibrate (31), picafibrate (35), ponfibrate (37), ronifibrate (55), salafibrate (41), serfibrate (34), simfibrate (22), sitofibrate (32), tiafibrate (33), timofibrate (40), tocofibrate (33), urefibrate (37), xantifibrate (31)

 

clofibric acid (20), clofibrate (13), aluminium clofibrate (31), calcium clofibrate (34), cinnarizine clofibrate (38), etofylline clofibrate (38), magnesium clofibrate (31)

 

clofibride (28), plafibride (39)

 

related: beclobrate (35), eniclobrate (39), gemfibrozil (34), halofenate (20), lifibrol (62), metibride (53), terbufibrol (35), tibric acid (33), (fibrafylline (43) deleted)

(b)

bromebric acid (25) (prophylaxis of migraine), fibracillin (30) (antibiotic)

(c)

nafenopin (24), treloxinate (25)

TRS 581

 

-flapon

5-lipoxygenase-activating protein (FLAP) inhibitor

K.0.0.0

 

J.0.0.0

 
 

quiflapon (72)

-flurane

halogenated compounds used as general inhalation anaesthetics

A.1.1.0

 

(a)

aliflurane (36), cryofluorane (6), desflurane (62), enflurane (25), isoflurane (28), methoxyflurane (11), norflurane (20), roflurane (12), sevoflurane (25), teflurane (12)

(b)

apaflurane (73)

(c)

halothane (6)

TRS 581

 

perfl(u)-

perfluorinated compounds used as blood substitutes and/or diagnostic agents

(a)

perflexane (82), perfluamine (45), perflubrodec (87), perflubron (66), perflunafene (45), perflutren (82)

 

USAN

-formin (d)

antihyperglycaemics, phenformin derivatives

M.5.0.0

(USAN: oral hypoglycemics (phenformin type))

 

(a)

benfosformin (29), buformin (17), etoformin (34), metformin (21), phenformin (10), tiformin (22)

TRS 581

 

-fos

insecticides, anthelminthics, pesticides etc., phosphorous derivatives

(-vos)

 

S.3.1.0

 

Y.0.0.0

 

1.

organophosphorous derivatives:

 

(a)

vet. insecticides:

 

quintiofos (25)

(b)

toldimfos (23) (vet. phosphorous source)

(c)

vet. insecticides and anthelminthics:

 

metrifonate (16)

 

anthelmintic: butonate (30)

2.

phosphates:

 

(a)

vet. insecticides:

 

clofenvinfos (23)

 

vet. anthelminthics:

 

bromofenofos (43), dichlorvos (28), naftalofos (16)

 

anthelminthics:

 

vincofos (28)

(b)

triclofos (13) (hypnotic, sedative)

(c)

vet. anthelminthics:

 

fospirate (21), haloxon (16)

3.

phosphorothioates:

 

 

vet. insecticides:

(a)

bromofos (25), coumafos (16), fenclofos (23), temefos (31)

(c)

dimpylate (16), phoxim (20) (vet. insecticide and anthelmintic), pyrimitate (16)

4.

phosphorodithioates:

 

(a)

benoxafos (22) (vet. pesticide)

(c)

carbofenotion (23) (vet. insecticide), dioxation (16) (vet. insecticide), (malathion (46) (deleted!))

5.

phosphoramidates

 

 

crufomate (16), uredofos (37)

 

anthelminthic:

 

imcarbofos (44)

-fos- or fos-

various pharmacological categories belonging to fos (other than those above):

 

-fos-

 

alafosfalin (41), amifostine (44), belfosdil (61), benfosformin (29), butafosfan (38), cifostodine (50), creatinolfosfate (20), dexfosfoserine (68), ferpifosate sodium (69), fosmenic acid (49), fosopamine (69), fosquidone (64), furifosmin (70), monophosphothiamine (8), sodium picofosfate (37), sparfosic acid (46), technetium (99mTc), tetrofosmin (66), trifosmin (74)

 

-fosfamide alkylating agents of the cyclophosphamide group

 

cyclophosphamide (10), defosfamide (12), glufosfamide (77), ifosfamide (23), mafosfamide (51), perfosfamide (66), sufosfamide (36), trofosfamide (23)

 

-fosine cytostatic

 

edelfosine (59), fostriecin (55), ilmofosine (56), miltefosine (61), perifosine (78)

 

fos-

 

fosarilate (53), fosazepam (27), foscarnet sodium (42), foscolic acid (12), fosenazide (46), fosfestrol (15), fosfocreatinine (50), fosfomycin (25), fosfonet sodium (35), fosfosal (37), fosfructose (81), fosmidomycin (46), fostedil (51)

-fradil

alcium channel blockers acting as vasodilators

F.2.1.0

 
 

mibefradil (72)

-frine

see -drine

 

USAN

-fungin

antifungal antibiotics (18th Report, 1968)

S.6.0.0

(USAN: antifungal antibiotics (undefined group))

S.4.3.0

 

(a)

abafungin (74), anidulafungin (81), basifungin (72), caspofungin (80), cilofungin (60), fusafungine (15), kalafungin (20), micafungin (84), nifungin (24), oxifungin (40), sinefungin (39), triafungin (40)

TRS 581

 
 

USAN

-fylline

N-methylated xanthine derivatives

B.1.0.0

(a)

acefylline clofibrol (44), acefylline piperazine (14), albifylline (66), aminophylline (4), apaxifylline (71), arofylline (75), bamifylline (15), cipamfylline (71), denbufylline (55), dimabefylline (19), diniprofylline (18), diprophylline (1), doxofylline (47), enprofylline (44), etamiphylline (6), etofylline (14), etofylline clofibrate (38), fibrafylline (43) (deleted), flufylline (48), fluprofylline (50), furafylline (48), guaifylline (16), isbufylline (62), laprafylline (60), lisofylline (72), lomifylline (37), mercurophylline (1), metescufylline (15), mexafylline (48), midaxifylline (79), naxifylline (86), nestifylline (64), pentifylline (29), pentoxifylline (29), perbufylline (58), pimefylline (21), propentofylline (46), proxyphylline (10), pyridofylline (14), spirofylline (58), stacofylline (73), tazifylline (52), theophylline ephedrine (14), torbafylline (56), triclofylline (19), verofylline (43), visnafylline (24), choline theophyllinate (8), fenetylline (16)

(c)

cafedrine (14), dimenhydrinate (1), dimethazan (8), meralluride (1), mercumatilin sodium (4), piprinhydrinate (8), promethazine teoclate (10), protheobromine (14), theodrenaline (14), xantifibrate (31), xantinol nicotinate (16)

 

radicals and groups: teprosilate (29)

TRS 581

 
 

USAN

gab

gabamimetic agents

E.0.0.0

 

(a)

fengabine (53), gabapentin (46), gaboxadol (48) (used as analgesic), pivagabine (66), pregabalin (78), progabide (43) (used as antiepileptic), retigabine (76), tiagabine (63), tolgabide (53), vigabatrin (52) (anticonvulsants)

(b)

gabexate (35) (proteolytic)

 

USAN

gado-

diagnostic agents, gadolinium derivatives

U.0.0.0

 

(a)

gadobenic acid (64), gadobutrol (66), gadocoletic acid (85), gadodiamide (63), gadomelitol (85), gadopenamide (60), gadopentetic acid (50), gadoteric acid (59), gadoversetamide (71), gadoxetic acid (71)

 

USAN

-gatran

thrombin inhibitor, antithrombotic agent

I.2.0.0

 

(a)

dabigatran (83), dabigatran etexilate (87), efegatran (71), inogatran (72), melagatran (74), napsagatran (72), ximelagatran (84)

(c)

argatroban (57)

 

BAN, USAN

gest (x)

steroids, progestogens

Q.2.2.0

(USAN: -gest-: progestins)

(a)

altrenogest (46), anagestone (16), cingestol (20), clogestone (21), clomegestone (20), demegestone (24), desogestrel (38), dexnorgestrel (30), dienogest (49), dydrogesterone (12), edogestrone (22), etonogestrel (65), flugestone (16), gestaclone (23), gestadienol (22), gestodene (37), gestonorone caproate (16), gestrinone (39), haloprogesterone (11), hydroxyprogesterone (8), levonorgestrel (33) (previously dexnorgestrel), medrogestone (15), medroxyprogesterone (10), medoxyprogesterone (10), medrogestone (15), megestrol (13), melengestrol (13), metogest (33), norelgestromin (83), norgesterone (14), norgestimate (35), norgestomet (32), norgestrel (17), norgestrienone (18), oxogestone (19), pentagestrone (14), progesterone (4), proligestone (28), promegestone (38), quingestanol (15), quingestrone (13), tigestol (20), tosagestin (86), trengestone (22), trimegestone (66)

(b)

algestone (22) (glucorticoid)

(c)

allylestrenol (10), chlormadinone (12), cismadinone (12), delmadinone (23), dimethisterone (8), ethisterone (4), ethynerone (17), etynodiol (13), hydromadinone (12), lynestrenol (13), metynodiol (27), norethisterone (6), noretynodrel (13), norvinisterone (10)

 

clometerone (15) (antiestrogen), dimepregnen (24) (antiestrogen)

 

USAN

-giline

MAO-inhibitors type B

C.3.1.0

 

(a)

clorgiline (23), mofegiline (69), pargiline (13), rasagiline (70), selegiline (39)

-gillin

antibiotics produced by Aspergillus strains (16th Report, 1966)

S.6.0.0

 

(a)

fumagillin (1), mitogillin (17)

(c)

mitosper (24), nifungin (24)

 

BAN, USAN

gli (x)

antihyperglycaemics, sulfonamide derivatives

(previously gly-)

 

M.5.2./3.0

(BAN: sulphonamide hypoglycaemics)

 

(USAN: gli-: oral hypoglycemics (glipizide type))

(a)

gliamilide (33), glibenclamide (18), glibornuride (22), glibutimine (31), glicaramide (28), glicetanile (37), gliclazide (25), (deleted: glidanile (23)), glicondamide (44), glidazamide (24), gliflumide (33), glimepiride (53), glipalamide (62), (glipentide (27) replaced by glisentide (58)), glipizide (27), gliquidone (28), glisamuride (45), glisentide (58) (previously glipentide), glisindamide (43), glisolamide (43), glisoxepide (24), glybuthiazol (8), glybuzole (15), glyclopyramide (17), glycyclamide (12), glyhexamide (15), glymidine sodium (15), glyoctamide (14), glyparamide (USAN only), glypinamide (13), glyprothiazol (8), glysobuzole (12)

(b)

glycerol (4), glycobiarsol (1), glycopyrronium bromide (12)

(c)

1.: acetohexamide (12), butadiazamide (10), chlorpropamide (8), heptolamide (12), metahexamide (10), thiohexamide (12), tolazamide (12), tolbutamide (6), tolpentamide (12), tolpyrramide (13)

 

2. other than sulfonamide derivatives: balaglitazone (84), camiglibose (67), ciglitazone (50), darglitazone (69), deriglidole (66), emiglitate (55), englitazone (64), farglitazar (84), ingliforib (85), isaglidole (61), linogliride (48), meglitinide (34), midaglizole (57), miglitol (55), mitiglinide (78), naglivan (65), nateglinide (77), netoglitazone (85), pioglitazone (60), pirogliride (40), ragaglitazar (85), reglitazar (84), repaglinide (65), rivoglitazone (84), rosiglitazone (78), tesaglitazar (85), tibeglisene (64), troglitazone (68), voglibose (65)

 

3. peptide: seglitide (57)

TRS 581

 

-golide

dopamine receptor agonists, ergoline derivatives

E.1.1.0

(a)

adrogolide (82), naxagolide (60), pergolide (41), quinagolide (62), voxergolide (61)

(c)

rotigotine (83)

-grastim

see -stim

 

USAN

-grel-

platelet aggregation inhibitors

-grel

 

I.2.1.0

(USAN: platelet antiaggregants (undefined group))

(a)

anagrelide (42), camonagrel (61), cangrelor (82), clopidogrel (57), dazmegrel (51), furegrelate (53), isbogrel (59), itazigrel (56), midazogrel (53), nafagrel (64), nicogrelate (48), oxagrelate (47), ozagrel (55), pamicogrel (70), pirmagrel (53), ridogrel (59), rolafagrel (65), samixogrel (72), sarpogrelate (63), satigrel (67), sunagrel (52), terbogrel (75), trifenagrel (53)

 

USAN

guan-

antihypertensives, guanidine derivatives

H.3.0.0

(USAN: anti-hypertensive substances (guanidine type))

 

(a)

guanabenz (26), guanacline (16), guanadrel (20), guanazodine (27), guancidine (18), guanclofine (36), guanethidine (11), guanfacine (35), guanisoquine (15), guanoclor (15), guanoctine (16), guanoxan (15), guanoxabenz (31), guanoxyfen (16), guabenxan (32)

(c)

guabenxan (32)

-ibine

see -ribine

 

USAN

-icam

anti-inflammatory, isoxicam derivatives

A.4.2.0

(USAN: anti-inflammatory agents (isoxicam group))

 

(a)

ampiroxicam (56), droxicam (52), enolicam (45), isoxicam (30), lornoxicam (59), meloxicam (52), piroxicam (32), sudoxicam (27), tenoxicam (44), tesicam (25)

 

USAN

-ifene

antiestrogens, clomifene and tamoxifen derivatives

(Q.2.1.0 L.6.0.0)

(a)

acolbifene (86), arzoxifene (80), bazedoxifene (86), clomifene (12), droloxifene (53), enclomifene (33), idoxifene (68), lasofoxifene (81), levormeloxifene (73), miproxifene (74), nitromifene (33), ormeloxifene (69), ospemifene (85), panomifene (58), pipendoxifene (84), raloxifene (54), tamoxifen (28), tesmilifene (81), toremifene (53), trioxifene (41), zindoxifene (54), zuclomifene (33), clomifenoxide (54)

(b)

dextropropoxyphene (7), levopropoxyphene (7), suloxifen (30) (bronchodilator)

(c)

nafoxidine (16)

-igetide

see -tide

 

USAN

-ilide

class III antiarrhythmics, sematilide derivatives

H.2.0.0

(a)

ambasilide (59), artilide (67), azimilide (72), dofetilide (65), ersentilide (72), ibutilide (63), ipazilide (62), risotilide (62), sematilide (58), trecetilide (79)

(b)

bromacrylide (13), ftaxilide (32), gliamilide (33)

 

USAN

imex (d)

immunostimulants

S.7.0.0

 

(a)

azimexon (40), forfenimex (55), imexon (37), roquinimex (53), ubenimex (56)

 

USAN

-imod

immunomodulators, both stimulant/suppressive and stimulant

S.7.0.0

 

(a)

atiprimod (75), cridanimod (83), defoslimod (79), esonarimod (79), glaspimod (74), iguratimod (86), imiquimod (66), ivarimod (60), laquinimod (85), pidotimod (63), resiquimod (82), susalimod (73), tiprotimod (57)

 

USAN

-imus

immunosuppressants (other than antineoplastics)

S.7.0.0

 

(a)

abetimus (81), anisperimus (82), everolimus (82), gusperimus (68), iguratimod (86), laflunimus (70), laquinimod (85), napirimus (60), pimecrolimus (81), sirolimus (69), tacrolimus (66), tresperimus (75)

-ine (d)

alkaloids and organic bases

(a)

1120 (24.04%) INNs ending in -ine in Lists 1-48 of Proposed INNs

 

BAN, USAN

io- (x)

iodine-containing contrast media

U.1.1.0

 

(a)

iobenzamic acid (14), iobitridol (68), iobutoic acid (20), iocarmic acid (22), iocetamic acid (18), iocanlidic acid (77), iodamide (15), iodecimol (51), iodetryl (1), iodixanol (53), iodophthalein sodium (1), iodoxamic acid (26), iofendylate (12), iofratol (67), ioglicic acid (33), ioglucol (41), ioglucomide (41), ioglunide (40), ioglycamic acid (15), iohexol (43), iolidonic acid (26), iolixanic acid (26), iomeglamic acid (26), iomeprol (54), iomorinic acid (37), iopamidol (40), iopanoic acid (1), iopentol (52), iophenoic acid (4), ioprocemic acid (39), iopromide (44), iopronic acid (28), iopydol (14), iopydone (14), iosarcol (54), iosefamic acid (14), ioseric acid (33), iosimide (50), iosulamide (39), iosumetic acid (33), iotalamic acid (13), iotasul (43), iotetric acid (37), iotranic acid (28), iotriside (60), iotrizoic acid (22), iotrolan (51), iotroxic acid (32), ioversol (56), ioxabrolic acid (53), ioxaglic acid (37), ioxilan (59), ioxitalamic acid (22), ioxotrizoic acid (33), iozomic acid (24)

(c)

adipiodone (4), bunamiodyl (10), dimethiodal sodium (1), diodone (1), ethyl cartrizoate (12), methiodal sodium (1), metrizamide (26), pheniodol sodium (1), phenobutiodil (6), propyl docetrizoate (10), propyliodone (1), sodium acetrizoate (4), sodium amidotrizoate (4), sodium diprotrizoate (6), sodium metrizoate (13), sodium tyropanoate (12)

TRS 581

 

iod-)

iodine-containing compounds other than contrast media

-io-)

 

io(d)-/-io-

iodine-containing radiopharmaceuticals

(a)

ethiodized oil (131I) (24), iobenguane (131I) (57), iodinated (125I) human serum albumin (24), iodinated (131I) human serum albumin (24), iodocetylic acid (123I) (47), iodocholesterol (131I) (39), iofetamine (123I) (51), iolopride (123I) (73), iomazenil (123I) (66), iometin (125I), iometin (131I) (24), sodium iodide (125I) (24), sodium iodide (131I) (24), sodium iodohippurate (131I) (24), sodium iotalamate (125I (24), sodium iotalamate (131I) (24)

(c)

fibrinogen (125I), macrosalb (131I) (33), rose bengal (131I) sodium (24), tolpovidone (131I) (24)

 

USAN

-irudin

hirudin derivatives

I.2.1.0

 
 

bivalirudin (72), desirudin (70), lepirudin (73), pegmusirudin (77)

 

USAN

-isomide

antiarrhythmics, disopyramide derivatives

H.2.0.0

(a)

actisomide (60), bidisomide (63), pentisomide (59)

(c)

disopyramide (12)

 

BAN, USAN

-ium (x)

qarternary ammonium compounds

   
 

(USAN: -ium or onium)

 

USAN

E.3.0.0

neuromuscular blocking agents with a flexible structure

(a)

azamethonium bromide (1), decamethonium bromide (1), dicolinium iodide (25), dimecolinium iodide (14), fubrogonium iodide (18), hexamethonium bromide (1), mebezonium iodide (16), oxapropanium iodide (1), oxydipentonium chloride (1), pentamethonium bromide (1), pentolonium tartrate (4), prodeconium bromide (6), stilonium iodide (32), suxamethonium chloride (1), suxethonium chloride (1), tetrylammonium bromide (1), tiametonium iodide (15), trepirium iodide (25)

(c)

gallamine triethiodide (1)

E.3.0.0

neuromuscular blocking agents with rigid structure

 

(USAN: -curium, also curonium; neuromuscular blocking agents; quaternary ammonium derivatives)

(a)

alcuronium chloride (17), atracurium besilate (42), candocuronium iodide (70), cisatracurium besilate (73), dacuronium bromide (21), dimethyltubocurarinium chloride (1), doxacurium chloride (58), fazadinium bromide (32), hexafluronium bromide (12), laudexium metilsulfate (4), mivacurium chloride (58), pancuronium bromide (19), pentacynium chloride (6), phenactropinium chloride (8), pipecuronium bromide (69), piprocurarium iodide (11), rapacuronium bromide (78), rocuronium bromide (66), stercuronium iodide (21), thiazinamium metilsulfate (37), trimethidinium methosulfate (8), truxicurium iodide (22), truxipicurium iodide (22), vecuronium bromide (46)

(c)

tubocurarine chloride (1)

E.1.0.0

cholinergic agents

(a)

aclatonium napadisilate (44), ambenonium chloride (6), benzpyrinium bromide (1), carpronium chloride (23), demecarium bromide (10), furtrethonium iodide (1)

(c)

acetylcholine chloride (4), charbacol (4), choline alfoscerate (29), choline chloride (4), choline gluconate (1), choline salicylate (15) (analgesic), choline theophyllinate (8) (smooth muscle relaxant), methacholine chloride (1), nitricholine perchlorate (6) (antihypertensive), distigmine bromide (16), ecothiopate iodide (6), neostigmine bromide (4), obidoxime chloride (16), pralidoxime iodide (10), pyridostigmine bromide (6)

E.2.0.0

anticholinergic agents

(a)

benzilonium bromide (13), benzopyrronium bromide (12), beperidium (57), bevonium metilsulfate (19), butropium bromide (30), ciclonium bromide (19), ciclotropium bromide (50), cimetropium bromide (51), clidinium bromide (6), cyclopyrronium bromide (12), dimetipirium bromide (37), diponium bromide (15), dotefonium bromide (24), droclidinium bromide (33), emepronium bromide (18), etipirium iodide (22), fenclexonium metilsulfate (20), fenpiverinium bromide (26), fentonium bromide (29), flutropium bromide (50), glycopyrronium bromide (12), heteronium bromide (14), hexasonium iodide (15), hexocyclium metilsulfate (6), hexopyrronium bromide (13), ipratropium bromide (31), methanthelinium bromide (1), methylbenactyzium bromide (34), metocinium iodide (26), nolinium bromide (37), otilonium bromide (38), oxapium iodide (26), oxitefonium bromide (18), oxitropium bromide (36), oxyphenonium bromide (1), oxypyrronium bromide (13), oxysonium iodide (15), pentapiperium metilsulfate (26), prifinium bromide (20), ritropirronium bromide (33), sintropium bromide (47), sultroponium (18), tematropium metilsulfate (64), tiemonium iodide (13), timepidium bromide (29), tiotropium bromide (67), tiquizium bromide (47), trantelinium bromide (24), trospium chloride (25), xenytropium bromide (15)

(c)

atropine methonitrate (4), buzepide metiodide (14), chlorisondamine chloride (6), diphemanil metilsulfate (4), homatropine methylbromide (1), isopropramide iodide (8), mepenzolate bromide (10), octatropine methylbromide (10), parapenzolate bromide (14), pipenzolate bromide (6), poldine metilsulfate (11), propantheline bromide (1), propyromazine bromide (12), tridihexethyl iodide (6), tropenziline bromide (11), thihexinol methylbromide (1), tricyclamol chloride (4)

S.2.3.0

surfactants used as antibacterials and antiseptics

(a)

acriflavinium chloride (1), amantanium bromide (39), benzalko-nium chloride (1), benzethonium chloride (1), benzododecinium chloride (1), benzoxonium chloride (36), cefalonium (16), cefmepidium chloride (57), cetalkonium chloride (15), cethexonium chloride (36), cetrimonium bromide (1), cetylpyridinium chloride (1), chlorphenoctium amsonate (8), deditonium bromide (15), denatonium benzoate (15), dequalinium chloride (8), disiquonium chloride (55), dodeclonium bromide (16), dofamium chloride (21), fludazonium chloride (33), furazolium chloride (15), halopenium chloride (10), hedaquinium chloride (8), lapirium chloride (27), lauralkonium chloride (62), laurcetium bromide (70), laurolinium acetate (12), mecetronium etilsulfate (51), metalkonium chloride (60), methylbenzethonium chloride (1), methylrosanilinium chloride (1), methylthioninium chloride (1), miripirium chloride (63), miristalkonium chloride (41), octafonium chloride (16), opratonium iodide (76), penoctonium bromide (20), pirralkonium bromide (19), polidronium chloride (67), polixetonium chloride (70), prolonium iodide (14), sanguinarium chloride (68), sepazonium chloride (34), tetradonium bromide (18), tibezonium iodide (32), tiodonium chloride (36), toliodium chloride (36), toloconium metilsulfate (17), tonzonium bromide (14), triclobisonium chloride (10)

(c)

domiphen bromide (23)

 

other agents

 

amezinium metilsulfate (36), amprolium chloride (16), azaspirium chloride (25), bephenium hydroxynaphthoate (11), bibenzonium bromide (12), bidimazium iodide (27), bretylium tosilate (10), butopyrammonium iodide (8), carcainium chloride (36), clofilium phosphate (42), datelliptium chloride (57), detajmium bitartrate (34), dibrospidium chloride (51), ditercalinium chloride (49), edrophonium chloride (4), elliptinium acetate (43), emilium tosilate (37), famiraprinium chloride (58), feniodium chloride (23), gallium (67Ga) citrate (33), homidiumbromide (36), isometamidium chloride (18), mefenidramium metilsulfate (52), meldonium (86), mequitamium iodide (61), nolpitantium besilate (75), pinaverium bromide (32), pirdonium bromide (28), prajmalium bitartrate (23), pranolium chloride (32), pretamazium iodide (29), propagermanium (65), prospidium chloride (22), pyritidium bromide (16), pyrvinium chloride (6), quindonium bromide (14), quinuclium bromide (40), repagermanium (63), rimazolium metilsulfate (26), roxolinium metilsulfate (33), samarium (153Sm) lexidronam (74), sevitropium mesilate (56), spirogermanium (43), stilbazium iodide (13), thenium closilate (12), tipetropium bromide (42), tolonium chloride (4), trazium esilate (54), trethinium tosilate (14), troxonium tosilate (13), troxypyrrolium tosilate (13)

(c)

alazanine triclofenate (13) (anthelminthic), colfosceril palmitate (64) (pulmonary surfactant), dithiazanine iodide (8) (anthel-minthic), hexadimethrine bromide (8) (heparin antagonist)

-curium (d)

curare-like substances

-izine

diphenylmethyl piperazine derivatives

(-yzine)

(a)

antihistaminics: G.2.0.0: buclizine (4), cetirizine (51), chlorcyclizine (1), clocinizine (15), cyclizine (1), efletirizine (71), elbanizine (60), flotrenizine (48), levocetirizine (78), pibaxizine (62), trenizine (48)

 

homochlorcyclizine (10) (serotonin antagonist)

 

tranquillizers: etodroxizine (18), hydroxyzine (6)

 

various: benderizine (40) (antiarrhythmic), decloxizine (19) (respiratory insufficiency), ropizine (36) (anticonvulsant)

-rizine

antihistaminics/cerebral (or peripheral) vasodilators

 

belarizine (36), buterizine (42), cinnarizine (11), dotarizine (50), flunarizine (22), lifarizine (66), tagorizine (72), tamolarizine (66), trelnarizine (62)

 

chemically related: pipoxizine (32) (respiratory insufficiency)

(b)

phenothiazine derivatives: chloracyzine (12) (vasodilator), fluacizine (25) (sedative), moracizine (25) (antiarrhythmic), tiracizine (62) (antiarrhythmic)

 

benzilate esters: benactyzine (6) (tranquillizer), benaprizine (26) (anti-parkinsonian)

 

phenylpiperazine: dimetholizine (10) (antiallergic), dropropizine (18)/levodropropizine (64) (antitussive)

 

antibiotic "cef": cefatrizine (34)

 

pyrazine derivatives: ampyzine (15) (central nervous stimulant), triampyzine (15) (anticholinergic)

 

indoloquinolines (anticholinergic): metoquizine (17), toquizine (17)

(c)

medibazine (16)

 

USAN

-kacin

antibiotics, kanamycin and bekanamycin derivatives (obtained from Streptomyces kanamyceticus)

S.6.3.0

(USAN: antibiotics obtained from Streptomyces kanamyceticus (related to kanamycin))

 

(a)

amikacin (30), arbekacin (56), butikacin (41), dibekacin (31), propikacin (43)

(c)

bekanamycin (24), kanamycin (10)

 

other aminoglycoside antibiotics:

 

Strept. griseus: dihydrostreptomycin (1) (semisynthetic), streptomycin (1), streptoniazid (13) (semisynthetic)

 

Strept. tenebrarius: apramycin (31), nebramycin (19) (mixture of several antibiotics, including apramycin and tobramycin), tobramycin (28)

 

Bacillus circularis: butirosin (25)

 

USAN

-kalant

potassium channel blockers

H.2.0.0

 

(a)

adekalant (83), almokalant (64), clamikalant (81), nifekalant (75), terikalant (66), pinokalant (82)

 

BAN, USAN

-kalim

potassium channel activators, antihypertensive

H.3.0.0

 

(a)

aprikalim (64), bimakalim (64), cromakalim (58)/levcromakalim (66), emakalim (66), mazokalim (75), rilmakalim (65), sarakalim (81)

 

USAN

-kef-

enkephalin agonists

 

casokefamide (65), frakefamide (81), metkefamide (44)

-kin

interleukin type substances

S.7.0.0

 

IL-1:

-nakin

interleukin-1 analogues and derivatives:

 

-onakin

interleukin-1 analogues and derivatives: pifonakin (77)

 

-benakin

interleukin-1 analogues and derivatives: mobenakin (72)

IL-2:

-leukin

interleukin-2 analogues and derivatives: aldesleukin (63), celmoleukin (65), denileukin diftitox (78), teceleukin (54)

   

pegaldesleukin (67)

IL-3:

-plestim

interleukin-3 analogues and derivatives: muplestim (72)

IL-4:

-trakin

interleukin-4 analogues and derivatives: binetrakin (82)

IL-6:

-exakin

interleukin-6 analogues and derivatives: atexakin alfa (72)

IL-8:

-octakin

interleukin-8 analogues and derivatives: emoctakin (74)

IL-10:

-decakin

interleukin-10 analogues and derivatives: ilodecakin (81)

IL-11:

-elvekin

interleukin-11 analogues and derivatives: oprelvekin (76)

 

-kinra

interleukin receptor antagonists: pitrakinra (84)

IL-12:

-dodekin

interleukin-12 analogues and derivatives: edodekin alfa (79)

IL-13:

-nakinra

interleukin-1 receptor antagonists: anakinra (72)

 

USAN

-kiren

renin inhibitors

 

H.3.0.0

 

(a)

aliskiren (83), ciprokiren (69), ditekiren (62), enalkiren (61), remikiren (66), terlakiren (66), zankiren (70)

 

USAN

-lubant

leukotriene B4 receptor antagonist

(a)

amelubant (85), moxilubant (78), ticolubant (76)

-lukast

leukotriene receptor antagonists, see -ast

 

BAN, USAN

-mab

monoclonal antibodies (see also Annex)

S.7.0.0

 

-amab

rat origin

-emab

hamster origin

-imab

primate origin

-omab

mouse origin:

 
 

ba(c)

bacterial: edobacomab (69)

 

co(l)

colon: edrecolomab (74), nacolomab tafenatox (71)

 

go(v)

ovary (tumours): igovomab (74), oregovomab (86)

 

li(m)

lymphocyte: afelimomab (72), dorlimomab aritox (66), enlimomab (70), enlimomab pegol (77), faralimomab (76), gavilimomab (84), inolimomab (71), maslimomab (66), nerelimomab (76), odulimomab (73), telimomab aritox (66), vepalimomab (80), zolimomab aritox (69)

 

ci(r)

cardiovascular: biciromab (66), imciromab (66)

 

le(s)

infectious lesions: lemalesomab (84), sulesomab (75), technetium (99mTc) fanolesomab (86)

 

pr(o)

tumour (prostate): capromab (70)

 

tu(m)

tumour (miscellaneous): anatumomab mafenatox (79), arcitumomab (74), altumomab (68), bectumomab (75), detumomab (70), epitumomab (82), ibritumomab tiuxetan (81), minretumomab (80), mitumomab (82), satumomab (67), taplitumomab paptox (84), technetium (99mTc) nofetumomab merpentan (76), technetium (99mTc) pintumomab (75), tositumomab (80)

-umab

human origin:

 
 

ba(c)

bacterial: nebacumab (66)

 

li(m)

immunomodulator: adalimumab (82), atorolimumab (80), lerdelimumab (83), metelimumab (86), morolimumab (79), ziralimumab (84)

 

tu(m)

tumour: votumumab (70)

 

vi(r)

viral: regavirumab (71), sevirumab (66), tuvirumab (66)

-ximab

chimeric origin

 
 

ci(r)

cardiovascular: abciximab (70)

 

li(m)

immunomodulator: basiliximab (76), clenoliximab (77), infliximab (77), keliximab (76), priliximab (72), teneliximab (87), vapaliximab (87)

 
 

me(l)

melanoma: ecromeximab (87)

 

tu(m)

tumor: cetuximab (82), rituximab (77)

 

(c)

 

muromonab CD3 (59)

-zumab

humanized origin

 

ci(r)

cardiovascular: bevacizumab (83)

 
 

li(m)

lymphocyte: apolizumab (87), daclizumab (78) (previously: dacliximab), eculizumab (87), efalizumab (85), erlizumab (84), fontolizumab (87), mepolizuma (81), natalizumab (79), omalizumab (84), palivizumab (79), pascolizumab (87), pexelizumab (85), reslizumab (85), rovelizumab (81), ruplizumab (83), siplizumab (87), toralizumab (87), visilizumab (84)

 

tu(m)

tumor: (miscellaneous): alemtuzumab (83), bivatuzumab (83), cedelizumab (77), epratuzumab (82), gemtuzumab (83), labetuzumab (85), lintuzumab (76), sibrotuzumab (81), trastuzumab (78)

 
 

vi(r)

viral: felvizumab (77)

 
 

USAN

-mantadine

adamantane derivatives

-mantine

 

-mantone

 
 

(a)

antiviral: S.5.3.0: amantadine (15), rimantadine (17), somantadine (51), tromantadine (28)

 

antiparkinsonian: E.2.0.0: carmantadine (31), dopamantine (31), memantine (35)

 

immunostimulant: S.7.0.0: idramantone (71)

(b)

anthelminthic: S.3.1.0: dimantine (14)

(c)

adamexine (36) (mucolytic), amantocillin (17) (antibiotic), bolmantalate (16) (anabolic)

 

USAN

-meline

cholinergic agents (muscarine receptor agonists/partial antagonists used in the treatment of Alzheimer's disease)

E.1.0.0

 

alvameline (79), cevimeline (76), itameline (71), milameline (74), sabcomeline (76), tazomeline (77), xanomeline (70)

mer- or -mer- (d)

1mercury-containing drugs, antimicrobial or diuretic (deleted from General Principles in List 28 prop. INN)

(a)

S.2.2.0 antimicrobial: meralein sodium (13), merbromin (1), mercurobutol (1), otimerate sodium (51), phenylmercuric borate (4), sodium timerfonate (13), thiomersal (1)

 

1mer- and -mer- can be used for any type of substances and are no longer restricted to use in INNs for mercury-containing drugs (18th Consultation on INNs 1988)

 

N.1.3.0 diuretic: chlormerodrin (4), chlormerodrin (197 Hg) (24), meralluride (1), mercaptomerin (1), mercuderamide (1), mercumatilin sodium (4), mercurophylline (1), merisoprol (197 Hg) (24) (diagnostic), mersalyl (4)

(b)

difemerine (17) (spasmolyt.), dimercaprol (1) (antidote, -SH group), lomerizine (68), (cerebral vasodilator), mercaptopurine (6) (cytostatic, -SH group), nifurmerone (16), pemerid (25)

 

(antituss.), suxemerid (25) (antituss.)

(c)

hydrargaphen (10)

 

USAN

-mer

polymers:

(a)

amilomer (33), cadexomer (60), carbetimer (50), carbomer (21), crilanomer (53), dextranomer (33), eldexomer (51), leuciglumer (68), maletamer (14), poloxamer (34), porfimer sodium (64), sevelamer (77), surfomer (44), zinostatin stimalamer (74)

(b)

succimer (42)

-mesine

sigma receptor ligands

 

igmesine (68), panamesine (73), siramesine (81)

 

USAN

-mestane

aromatase inhibitors

L.0.0.0/Q.2.1.0

 
 

exemestane (65), formestane (66), minamestane (64)

met(h)asone

see pred

 

BAN, USAN

-metacin (x)

anti-inflammatory, indometacin derivatives

A.4.2.0

(BAN: anti-inflammatory substances of the indomethacin group)

 

(USAN: -methacin: anti-inflammatory substances (indomethacin type))

 

(a)

acemetacin (32), cinmetacin (24), clometacin (27), delmetacin (48) (originally demetacin (42)), duometacin (27), glucametacin (32), indometacin (13), niometacin (33), oxametacin (37), pimetacin (47), proglumetacin (35), sermetacin (36), talmetacin (46), zidometacin (39)

 

other anti-inflammatory, indole derivatives: etoprindole (22), indopine (12), indoxole (17), nictindole (28)

 

USAN

-micin

antibiotics obtained from various Micromonospora

(S.6.5.0)

(USAN: antibiotics (Micromonospora strains))

 

astromicin (44), betamicin (38), etisomicin (47), evernimicin (82), gentamicin (22), isepamicin (54), maduramicin (52), megalomicin (37), micronomicin (45), mirosamicin (58), netilmicin (36), ozogamicin (83), pentisomicin (41), repromicin (37), rosaramicin (41) (prev. rosamicin), semduramicin (60), sisomicin (25)

TRS 581

 

-mifene

see -ifene

mito- (d)

antineoplastics, nucleotoxic agents (deleted from General Principles in List 24 prop. INN)

L.0.0.0

 

(a)

mitobronitol (20), mitocarcin (25), mitoclomine (18), mitoflaxone (60), mitogillin (17), mitoguazone (20), mitolactol (26), mitomalcin (19), mitomycin (26), mitonafide (40), mitopodozide (17), mitoquidone (54), mitosper (24), mitotane (21), mitotenamine (17), mitoxantrone (44), mitozolomide (51)

 

mitindomide (48)

 

USAN

-monam

monobactam antibiotics

S.6.0.0

(a)

carumonam (51), gloximonam (54), oximonam (54), pirazmonam (58), tigemonam (57)

(c)

aztreonam (48)

 

USAN

-mostim

see -stim

 

USAN

-motine

antivirals, quinoline derivatives (19th Report 1970)

S.5.3.0

(USAN: antiviral quinoline derivatives)

 

 

famotine (23), memotine (22)

-moxin (d)

monoamine oxidase inhibitors, hydrazine derivatives*

C.3.1.0

 

(a)

benmoxin (20), cimemoxin (17), domoxin (14), octamoxin (15)

         
 

*not part of definition

(c)

carbenzide (11), etryptamine (12), fenoxypropazine (12), iproclozide (13), iproniazid (1), isocarboxazid (11), mebanazine (15), nialamide (10), pargyline (13), phenelzine (10), pheniprazine (11), tranylcypromine (11)

TRS 581

 
 

USAN

-mustine

antineoplastic, alkylating agents, (β-chloroethyl)amine derivatives

   

L.2.0.0

(USAN: antineoplastic agents ([β-chlorethyl]amine derivatives))

 

(a)

alestramustine (68), ambamustine (60), atrimustine (61), bendamustine (48), bofumustine (44), carmustine (24), ditiomustine (49), ecomustine (61), elmustine (49), estramustine (24), fotemustine (57), galamustine (61), lomustine (27), mannomustine (8), neptamustine (48) (originally pentamustine (45)), nimustine (37), prednimustine (31), ranimustine (55), semustine (27), spiromustine (47), tallimustine (68), tauromustine (50), uramustine (13)

(c)

chlorambucil (6), chlormethine (1), chlornaphazine (1), cyclophosphamide (10), defosfamide (12), ifosfamide (23), mafosfamide (51), melphalan (8), mitoclomine (18), mitotenamine (17), perfosfamide (66), sarcolysin (17), sufosfamide (36), trichlormethine (11), trofosfamide (23)

TRS 581

 
 

BAN, USAN

-mycin (x)

antibiotics, produced by Streptomyces strains (see also -kacin)

S.6.0.0

(USAN: antibiotics, Streptomyces strains)

(a)

amfomycin (12), antelmycin (15), apramycin (31), avilamycin (46), azalomycin (26), azithromycin (58), bambermycin (21), bekanamycin (24), berythromycin (26), bicozamycin (38), biniramycin (23), bluensomycin (14), capreomycin (12), carbomycin (1), cethromycin (87), clarithromycin (59), clindamycin (21), coumamycin (15), daptomycin (58), dihydrostreptomycin (1), diproleandomycin (33), dirithromycin (53), efrotomycin (53), endomycin (6), enramycin (23), enviomycin (31), erythromycin (4), estomycin (14 - deleted in List 28), flurithromycin (51), fosfomycin (25), fosmidomycin (46), ganefromycin (68), hachimycin (23), heliomycin (25), hydroxymycin (8 - deleted in List 28), josamycin (23), kanamycin (10), kitasamycin (13), laidlo-mycin (61), lexithromycin (65), lincomycin (13), lividomycin (32), maridomycin (32), midecamycin (30), mikamycin (17), mirincamycin (31), mocimycin (28), natamycin (15), nebramycin (19), neomycin (1), neutramycin (15), oleandomycin (6), paldimycin (55), paromomycin (10), paulomycin (47), pirlimycin (47), primycin (38), pristinamycin (12), ranimycin (20), relomycin (15), ribostamycin (27), rifamycin (13), rokitamycin (53), roxithromycin (54), salinomycin (37), sedecamycin (55), spectinomycin (13), spiramycin (6), stallimycin (30), steffimycin (20), streptomycin (1), telithromycin (80), terdecamycin (65), tobramycin (28), troleandomycin (24), trospectomycin (53), tulathromycin (87) (vet.), vancomycin (6), viomycin (4), virginiamycin (18)

 

antibiotics, antineoplastics:

 

ambomycin (13), antramycin (17), azotomycin (13), bleomycin (23), cactinomycin (15), dactinomycin (18), duazomycin (13), lucimycin (13), mitomycin (26), nogalamycin (16), olivomycin (18), peliomycin (15), peplomycin (44), plicamycin (50) (previously mithramycin (16)), porfiromycin (15), puromycin (15), rufocromomycin (12), sparsomycin (13), talisomycin (41)

 

antibiotics, antineoplastics, antibacterial:

 

cirolemycin (21)

 

antibiotic, antifungal:

 

hamycin (17), lidimycin (20), rutamycin (14)

(c)

antibiotic, antibacterial:

 

aspartocin (11), azidamfenicol (14), cetofenicol (14), chloramphenicol (1), cloramfenicol pantotenate comp. (14), cycloserine (6), novobiocin (6), ostreogrycin (6), rifamide (15), rifampicin (17), streptoniazid (13), streptovarycin (6), thiamphenicol (10), tylosin (16)

 

antibiotic, antifungal:

 

amphotericin B (10), candicidin (17), filipin (20), kalafungin (20), nystatin (6), viridofulvin (16)

 

antibiotic, antineoplastic:

 

daunorubicin (20), mitomalcin (19), streptonigrin (14) (deleted in List 33)

 

see also -rubicin

 

USAN

nab

cannabinol derivatives

 

(USAN: -nab; or -nab-: cannabinol derivatives)

 

(a)

cannabinol (23), dronabinol (51), menabitan (49), nabazenil (49), nabilone (49), nabitan (42), naboctate (45), nonabine (47), pirnabin (41), rimonabant (83), tinabinol (49)

(b)

fenabutene (26), guanabenz (26), muromonab-CD3 (59), nabumetone (44)

 

USAN

nal-

narcotic antagonists/agonists related to normorphine

A.4.1.0

 

B.2.0.0

(USAN: arcotic agonists or antagonists related to normorphine)

 

a)

nalbuphine (21), nalfurafine (87), nalmefene (49) (originally nalmetrene (47)), nalmexone (19), nalorphine (1), naloxone (13), naltrexone (29)

(b)

nalidixic acid (13)

TRS 581

 

-naritide

see -tide

-nermin

see -ermin

-nercept

tumour necrosis factor antagonist

 

etanercept (81), lenercept (72), onercept (82)

nico- or nic- or ni-

nicotinic acid or nicotinoyl alcohol derivatives

 

 

nico-: nicoboxil (43), nicoclonate (29), nicocodine (12), nicocortonide (40), nicodicodine (15), nicofibrate (31), nicofuranose (14), nicofurate (28), nicomol (23), nicomorphine (7), nicopholine (1), nicorandil (44), nicothiazone (10), nicotinamide (4), nicotinic acid (4), nicotredole (72), nicoxamat (44), nikethamide (4)

 

inositol nicotinate (16), xantinol nicotinate (16)

 

nic-: nicafenine (40), nicainoprol (46), nicametate (15), nicardipine (42), nicanartine (72), nicergoline (26), niceritrol (23), niceverine (15), nictindole (28), nizofenone (44)

 

ni-: nialamide (10), niaprazine (24), nifenazone (15), niometacin (33), niprofazone (29), nixylic acid (17)

-nicate:

antihypercholesterolaemic and/or vasodilating nicotinic acid esters

H.4.0.0

 

F.2.2.0

 

(a)

ciclonicate (33), derpanicate (58), estrapronicate (34), glunicate (51), hepronicate (22), micinicate (44), pantenicate (56), sorbinicate (33)

(b)

nitrile derivative: nimazone (21)

 

other: nifungin (24), nimidane (34), nisbuterol (38)

(c)

NO2 - derivatives: acenocoumarol (6) (anticoag.), azathioprine (12) and tiamiprine (15) (antimetabolites), bronopol (14) (antiseptic), chloramphenicol (1) (antibiotic), clonazepam (22) (sed.), flurantel (25) (anthelmintic), flutamide (33) (nonsteroid anti-androgen)

nitro- or nitr- or nit- or ni- or -ni-

NO2 - derivatives

 

nifur- all INNs of this series (see under nifur-)

 

nitro-: nitroclofene (41), nitrocycline (14), nitrodan (15), nitrofural (1), nitrofurantoin (11), nitromifene (33), nitroscanate (33), nitrosulfathiazole (1), nitroxinil (19), nitroxoline (15)

 

nitr-: nitracrine (35), nitrafudam (40), nitramisole (33), nitraquazone (53), nitrazepam (16), nitrefazole (46), nitricholine perchlorate (6)

 

nit- and -nit-: nitarsone (17), ranitidine (41)

 

ni-: nibroxane (35), niclofolan (20), niclosamide (13), nidroxyzone (6), nifenalol (22), nihydrazone (10), nimesulide (44), nimorazole (22), niridazole (17)

 

ni-dipine: nicardipine (42), nifedipine (27), niludipine (38), nisoldipine (42), nitrendipine (42), vatamidipine (77)

 

-nidazole: for INNs of this series see under -nidazole

 

BAN, USAN

-nidazole (x)

antiprotozoals, metronidazole derivatives

S.3.3.0

(USAN: antiprotozoal substances (metronidazole type))

Y.0.0.0

(a)

abunidazole (52), azanidazole (38), bamnidazole (37), benznidazole (31), carnidazole (32), etanidazole (57), fexinidazole (37), flunidazole (21), ipronidazole (21), metronidazole (11), misonidazole (38), moxnidazole (33), ornidazole (28), panidazole (24), pimonidazole (57), pirinidazole (32), propenidazole (45), ronidazole (18), satranidazole (48), secnidazole (30), sulnidazole (33), ternidazole (34), tinidazole (21), tivanidazole (48)

(c)

dimetridazole (17), nimorazole (22), stirimazole (25)

TRS 581

 

-nidine

see -onidine

 

USAN

nifur- (d)

5-nitrofuran derivatives

S.2.1.0

(a)

nifuradene (16), nifuraldezone (17), nifuralide (34), nifuratel (17), nifuratrone (24), nifurdazil (16), nifurethazone (10), nifurfoline (20), nifurimide (18), nifurizone (22), nifurmazole (22), nifurmerone (16), nifuroquine (36), nifuroxazide (14), nifuroxime (11), nifurpipone (20), nifurpirinol (22), nifurprazine (16), nifurquinazol (18), nifursemizone (16), nifursol (20), nifurthiazole (14), nifurtimox (21), nifurtoinol (36), nifurvidine (17), nifurzide (37)

(c)

furalazine (13), furaltadone (17), furazolidone (13), furazolium chloride (15), furmethoxadone (8), levofuraltadone (17), nidroxyzone (6), nihydrazone (10), nitrofural (1), nitrofurantoin (11), thiofuradene (11)

TRS 581

 

-nil

see -azenil, also for -carnil, -quinil

 

USAN

-nixin

anti-inflammatory, anilinonicotinic acid derivatives

A.4.2.0

(a)

butanixin (32), clonixin (22), diclonixin (31), flunixin (31), isonixin (34), metanixin (31)

(c)

clonixeril (22), niflumic acid (17), nixylic acid (17)

TRS 581

 

-ol (d)

for alcohols and phenols (deleted from General Principles in 14th Report)

 

BAN, USAN

-olol (x)

β-adrenoreceptor antagonists

E.5.2.0

(BAN: beta-adrenoreceptor antagonists)

 

 

(BAN: beta adrenoreceptor blocking agents of the propranolol group)

 

(USAN: beta-blockers)

(a)

acebutolol (28), adaprolol (63), adimolol (50), afurolol (40), alprenolol (19), ancarolol (47), arnolol (56), arotinolol (48), atenolol (33), befunolol (39), betaxolol (40), bevantolol (36), bisoprolol (48), bometolol (42), bopindolol (42), bornaprolol (46), bucindolol (43), bucumolol (35), bufetolol (30), bunitrolol (28), bunolol (22), bupranolol (27), butocrolol (38), butofilolol (40), carazolol (36), carpindolol (42), carteolol (35), celiprolol (35), cetamolol (47), cicloprolol (48), cinamolol (44), cloranolol (41), crinolol (41) (replaced by pacrinolol (44)), dexpropranolol (21), diacetolol (41), draquinolol (54), ecastolol (56), epanolol (52), ericolol (50), esatenolol (76), esmolol (50), exaprolol (32), falintolol (53), flestolol (53), flusoxolol (50), idropranolol (31), imidolol (49) (replaced by adimolol (50)), indenolol (37), indopanolol (48), iprocrolol (39), isoxaprolol (45), landiolol (75), levobetaxolol (61), levobunolol (42), levomoprolol (58), mepindolol (36), metipranolol (38), metoprolol (30), moprolol (36), nadolol (34), nadoxolol (28), nafetolol (39), nebivolol (56), nipradilol (50) (previously nipradolol (49)), oxprenolol (20), pacrinolol (44), pafenolol (46), pamatolol (36), pargolol (36), penbutolol (25), penirolol (36), pindolol (23), pirepolol (48), practolol (23), primidolol (42), procinolol (25), propranolol (15), ridazolol (51), ronactolol (57), soquinolol (43), spirendolol (46), talinolol (28), tazolol (31), teoprolol (43), tertatolol (48), tienoxolol (56), tilisolol (57), timolol (29), tiprenolol (23), tolamolol (29), toliprolol (28), trigevolol (56), xibenolol (48), xipranolol (22)

(b)

Q.2.3.0: stanozolol (18) (anabolic steroid)

TRS 581

 

-alol

aromatic ring

-CH-CH2-NH-R related to -olols

   

OH

 

 

(USAN: combined alpha and beta blockers)

 

amosulalol (50), bendacalol (59), brefonalol (56), bufuralol (31), dexsotalol (74), dilevalol (50), labetalol (35), medroxalol (43), nifenalol (22), pronetalol (14), sotalol (18), sulfinalol (41), butidrine (16)

(c)

butidrine (16)

 

USAN

-olone

see pred

-one (d)

ketones

(a)

448 (9.62%) INNs ending in -one in Lists 1-48 of Proposed INNs

 

BAN, USAN

-onide

steroids for topical use, acetal derivatives

Q.3.0.0

 

(a)

acrocinonide (27), amcinonide (33), budesonide (37), ciclesonide (62), cicortonide (28), ciprocinonide (38), desonide (24), dexbudesonide (80), drocinonide (29), fluclorolone acetonide (22), fluocinolone acetonide (11), flumoxonide (38), fluocinonide (25), halcinonide (29), itrocinonide (62), nicocortonide (40), procinonide (38), rofleponide (72), tralonide (27), triamcinolone benetonide (36), triamcinolone furetonide (36), triamcinolone hexacetonide (15), triclonide (30)

(c)

amcinafal (25), amcinafide (25)

TRS 581

 

-onidine

antihypertensives, clonidine derivatives

H.3.0.0

(a)

apraclonidine (59) (control of intraocular pressure), benclonidine (42), brimonidine (66), clonidine (40), flutonidine (31), moxonidine (48), piclonidine (44), tolonidine (28)

 

related: alinidine (40) (analgesic)

-nidine

 

H.3.0.0

 

(a)

related antihypertensives: betanidine (13), indanidine (50), rilmenidine (57), tiamenidine (28)

(b)

muscle relaxant: tizanidine (43)

 

topical antiinfective: octenidine (43), pirtenidine (57)

 

antibacterial: sulfaguanidine (4)

 

vet. coccidiostat: robenidine (25)

(c)

dexlofexidine (48), levlofexidine (48), lofexidine (33)

-onium

see -ium

-opamine

see -dopa

 

BAN, USAN

-orex

anorexics

M.1.0.0

(BAN: anorexic agents, phenethylamine derivatives)

 

(USAN: anorexants)

(a)

acridorex (21), amfepentorex (16), aminorex (14), benfluorex (25), clobenzorex (18), cloforex (16), clominorex (14), difemetorex (41), etolorex (20), fenisorex (29), fenproporex (17), flucetorex (30), fludorex (19), fluminorex (14), formetorex (14), furfenorex (16), indanorex (30), mefenorex (19), morforex (26), oxifentorex (20), pentorex (16), picilorex (40), tiflorex (34)

(c)

amfebutamone (31), amfecloral (12), amfepramone (13), amfetamine (55), amfetaminil (40), benzfetamine (55), brolamfetamine (55), chlorphentermine (11), clortermine (22), dexamfetamine (55), dimetamfetamine (38), etilamfetamine (40), fenbutrazate (12),

 

fenfluramine (14), hexapradol (12), levamfetamine (12), mephentermine (6), ortetamine (13), phendimetrazine (11), phenmetrazine (6), phentermine (11)

TRS 581

 

orphan

narcotic antagonists/agonists, morphinan derivates

A.4.1.0

 

B.2.0.0

(USAN: -orphan: morphinan derivatives that are narcotic antagonists or agonists)

 

(a)

A.4.1.0: butorphanol (31), dextromethorphan (1), dextrorphan (1), dimemorfan (30), ketorfanol (49), levomethorphan (1), levophenacylmorphan (9), levorphanol (4), norlevorphanol (9), oxilorphan (31), phenomorphan (5), proxorphan (43), racemethorphan (1), racemorphan (1), xorphanol (48)

TRS 581

B.2.0.0: levallorphan (2)

-orph-

-orphine: acetorphine (17), alletorphine (25), buprenorphine (29), cyprenorphine (17), desomorphine (5), diprenorphine (21), etorphine (17), homprenorphine (25), methyldesorphine (5), methyldihydro-morphine (5), nalorphine (1), nicomorphine (7), normorphine (7)

 

-orphinol: hydromorphinol (11)

 

-orphone: conorfone (46), hydromorphone (1), oxymorphone (5), pentamorphone (60), semorphone (67)

(b)

emorfazone (44), morforex (26), morpheridine (6), orphenadrine (8)

-ox

antacids, aluminium derivatives: glucalox (13), sucralox (13)

-alox

 
 

-dox

antibacterials, quinazoline dioxide derivatives:

 

 

carbadox (19), ciadox (44), cinoquidox (40), drazidox (24), mequidox (19), olaquindox (31), temodox (27)

 

-pirox

antimycotic pyridone derivatives:

 

 

ciclopirox (26), metipirox (26), rilopirox (56)

   
 

USAN

 

-xanox

anti-allergics, tixanox group:

 

(a)

amlexanox (55), mepixanox (49), sudexanox (44), tixanox (37), traxanox (44)

(c)

xanoxic acid (33)

others:

bifeprunox (87) (antipsychotic), cefminox (53) (antibiotic), deferasirox (86) (chelating agent), nifurtimox (21) (antiprotozoal), sulbenox (37) (animal growth regulator), acipimox (33) (antilipemic), etofenprox (57) (insecticide)

 

BAN, USAN

-oxacin (x)

antibacterials, nalidixic acid derivatives

S.5.5.0

(BAN: antibacterial agents of the cinoxacin group)

 

(USAN: antibacterial agents (nalidixic acid type))

 

(a)

alatrofloxacin (75), amifloxacin (51), balofloxacin (71), binfloxacin (60), cadrofloxacin (81), cetefloxacin (68), cinoxacin (32), ciprofloxacin (50), clinafloxacin (67), danofloxacin (61), difloxacin (55), droxacin (36), ecenofloxacin (78), enoxacin (49), enrofloxacin (56), esafloxacin (60), fandofloxacin (78), finafloxacin (85), fleroxacin (56), garenoxacin (87), gatifloxacin (74), gemifloxacin (81), grepafloxacin (68), ibafloxacin (60), irloxacin (53), levofloxacin (64), lomefloxacin (58), marbofloxacin (65), merafloxacin (69), miloxacin (40), moxifloxacin (78), nadifloxacin (64), norfloxacin (46), ofloxacin (49), olamufloxacin (79), orbifloxacin (68), pazufloxacin (71), pefloxacin (45), pradofloxacin (84), premafloxacin (72), prulifloxacin (72), rosoxacin (36), rufloxacin (57), sarafloxacin (62), sitafloxacin (75), sparfloxacin (63), temafloxacin (58), tioxacin (34), tosufloxacin (60), trovafloxacin (73), vebufloxacin (69)

(c)

flumequine (34), nalidixic acid (13), oxolinic acid (15), pipemidic acid (32), piromidic acid (27)

 

metioxate (34)

 

USAN

-oxan(e)

benzodioxane derivatives

E.5.1.0

(USAN: -adrenoreceptor antagonists; benzodioxane derivatives)

 

(a)

-adrenoreceptor antagonists

 

azaloxan (52) (antidepressant), fluparoxan (58) (antidepressant), idazoxan (49) (α2), imiloxan (52) (α2) (antidepressant), piperoxan (1) (sympatholytic), proroxan (39)

 

antihypertensives:

 

flesinoxan (55), guabenxan (32), guanoxan (15)

 

tranquillizers:

 

butamoxane (12), ethomoxane (12), pentamoxane (12)

 

related:

 

efaroxan (59) (α2)

(b)

ambenoxan (21), amoproxan (22), nibroxane (35), razoxane (40)/dexrazoxane (62), sobuzoxane (62), tolboxane (12)

 

USAN

-oxanide

see -anide

 

USAN

-oxef

see cef-

-oxepine

see -pine

 

USAN

-oxetine

antidepressants, fluoxetine derivatives

C.3.0.0

(a)

ansoxetine (58), dapoxetine (65), duloxetine (68), femoxetine (36), fluoxetine (34), ifoxetine (54), litoxetine (64), nisoxetine (34), omiloxetine (76), paroxetine (38), reboxetine (54), seproxetine (66), tomoxetine (49)

-oxifene

see -ifene

-oxicam

see -icam

 

BAN, USAN

-pafant

platelet-activating factor antagonists

I.2.1.0

 

(a)

apafant (60), bepafant (60), dacopafant (63), foropafant (75), israpafant (76), lexipafant (70), minopafant (80), modipafant (65), nupafant (70), rocepafant (71), setipafant (72), tulopafant (64)

 

USAN

-pamide

diuretics, sulfamoylbenzoic acid derivatives

 

(could be sulfamoylbenzamide) (19th Report, 1970)

N.1.2.0

(USAN: diuretics (sulfamoylbenzoic acid derivatives))

 

(a)

alipamide (18), besulpamide (52), clopamide (13), indapamide (29), tripamide (44), xipamide (22), zidapamide (50) (previously isodapamide (47))

(b)

chlorpropamide (8) (hypoglycemic), isopropamide iodide (8) (anticholinergic)

(c)

bumetanide (24), chlortalidone (12), clorexolone (15), furosemide (14), sulclamide (15), tiamizide (16)

 

USAN

-pamil

coronary vasodilators, verapamil derivatives

F.2.1.0

(USAN: coronary vasodilators (verapamil type))

 

(a)

anipamil (49), dagapamil (52), devapamil (53), dexverapamil (65), emopamil (52), falipamil (48), gallopamil (38), levemopamil (62), nexopamil (67), ronipamil (51), tiapamil (43), verapamil (16)

 

related: bertosamil (64), bisaramil (60)

 

USAN

-parcin

for glycopeptide antibiotics

S.6.0.0

 

(a)

avoparcin (29), orientiparcin (72)

 

USAN

-parin

heparin derivatives including low molecular mass heparins

I.2.0.0

 

(a)

ardeparin sodium (68), bemiparin sodium (75), certoparin sodium (70), dalteparin sodium (64), enoxaparin sodium (52), heparin sodium (54), livaraparin calcium (85), minolteparin sodium (73), nadroparin calcium (65), parnaparin sodium (65), reviparin sodium (65), tinzaparin sodium (65)

-parinux

synthetic heparinoids

 

fondaparinux sodium (83) (replaces fondaparin sodium (79))

 

USAN

-penem

analogues of penicillanic acid antibiotics modified in the five-membered ring

S.6.0.0

(USAN: analogues of penicillanic acid antibiotics modified in the five-membered ring)

 

(a)

biapenem (69), doripenem (83), ertapenem (84), faropenem (69), imipenem (50), lenapenem (73), meropenem (60), panipenem (64), ritipenem (67), sulopenem (68), tacapenem (87), tebipenem (82)

 

USAN

-perone

tranquillizers, neuroleptics, 4'-fluoro-4-piperidinobutyrophenone derivatives

 

C.1.0.0

 

C.2.0.0

(USAN: 4'-fluoro-4-piperidinobutyrophenone derivatives; antianxiety agents; neuroleptics)

(a)

aceperone (14), amiperone (14), biriperone (51), carperone (24), cicarperone (28), cinuperone (53), cloroperone (38), declenperone (42), duoperone (54), fenaperone (28), fluspiperone (34), lenperone (27), lodiperone (44), melperone (34), metrenperone (56), milenperone (37), mindoperone (38), moperone (14), nonaperone (44), pipamperone (17), pirenperone (46), prideperone (54), primaperone (17), propyperone (16), roxoperone (17), setoperone (51), spiperone (17), timiperone (40) closely related: azabuperone (34), azaperone (18), lodiperone (44), zoloperone (39)

 

USAN

-peridol

antipsychotics, haloperidol derivatives

 

benperidol (14), bromperidol (33), [clofluperol (18)], droperidol (14), [fluanisone (13)], haloperidol (10), trifluperidol (16)

 

USAN

-peridone

antipsychotics, risperidone derivatives

 

abaperidone (80), belaperidone (78), cloperidone (17), iloperidone (69), lusaperidone (82), ocaperidone (64), paliperidone (83), risperidone (57), tioperidone (37)

(c)

domperidone (36), etoperidone (36) (antiemetic)

 

USAN

-pidem

hypnotics/sedatives, zolpidem derivatives

C.1.0.0

 
 

alpidem (53), necopidem (66), saripidem (67), zolpidem (53)

-pin(e)

see also Pharm S/Nom 970 (tricyclic compounds)

-dipine

see -dipine

(a)

 

-zepine

antidepressant/neuroleptic: C.3.2.0: dibenzepin (14), elanzepine (35), enprazepine (30), mezepine (22), nuvenzepine (59), prazepine (15), propizepine (19), tilozepine (40)

 

tricyclic antiulcer: J.0.0.0: darenzepine (52), pirenzepine (30), siltenzepine (63), telenzepine (50), zolenzepine (48)

 

tricyclic anticonvulsant: A.3.1.0: carbamazepine (15), etazepine (51), licarbazepine (81), oxcarbazepine (41)

 

hyperthermia: amezepine (42)

-apine

psychoactive: C.0.0.0: amoxapine (25), asenapine (87), batelapine (64), clotiapine (16), clozapine (22), flumezapine (47), fluperlapine (46), loxapine (22), metiapine (22), mirtazapine (61), olanzapine (67), pentiapine (56), perlapine (23), quetiapine (74), rilapine (52), serazapine (63), tenilapine (52)

-cilpine

antiepileptic: A.3.1.0: dizocilpine (60)

-oxepin

beloxepin (75), cidoxepin (17), doxepin (15), maroxepin (54), metoxepin (33), pinoxepin (18), savoxepin (56), spiroxepin (32)

-oxopine

traboxopine (58)

-sopine

adosopine (63)

-tepine

citatepine (54), clorotepine (29), damotepine (27), metitepine (27), tropatepine (28)

 

dosulepin (15)

(b)

atromepine (15), noscapine (7), prozapine (14)

(c)

clobenzepam (25), homopipramol (20), opipramol (15)

-piprazole

see -prazole

 

USAN

-pirox

see -ox

-pirone

see -spirone

-plact

platelet factor 4 analogues and derivatives

 

iroplact (74)

 

USAN

-planin

antibacterials (Actinoplanes strains)

S.5.0.0

 
 

actaplanin (34), mideplanin (66), ramoplanin (57), teicoplanin (48)

-plase

see -teplase, -uplase under -ase

 

USAN

-platin

antineoplastic agents, platinum derivatives

L.0.0.0

(USAN: antineoplastics (platinum derivatives))

(a)

carboplatin (48), cisplatin (39), dexormaplatin (64), enloplatin (64), eptaplatin (83), iproplatin (51), lobaplatin (65), miboplatin (66), miriplatin (85), nedaplatin (67), ormaplatin (63), oxaliplatin (56), picoplatin (87), satraplatin (80), sebriplatin (68), spiroplatin (48), triplatin tetranitrate (87), zeniplatin (63)

-plon

pyrazolo[.]pyrimidine derivatives, used as anxiolytics, sedatives, hypnotics

A.2.2.0

 

C.1.0.0

 
 

ocinaplon (72), indiplon (86), zaleplon (72)

 

BAN, USAN

-poetin

erythropoietin type blood factors

I.0.0.0

 

(a)

darbepoetin alfa (85), epoetin alfa (62), epoetin beta (62), epoetin delta (85), epoetin gamma (67), epoetin epsilon (72), epoetin omega (73)

 

USAN

-porfin

benzoporphyrin derivatives

(a)

rostaporfin (83), stannsoporfin (79), talaporfin (83), temoporfin (70), verteporfin (71)

-poride

Na+/H+ antiport inhibitor

 

amiloride (18), cariporide (74), eniporide (79), sabiporide (84), zoniporide (85)

 

BAN, USAN

-pramine

substances of the imipramine group

C.3.2.0

(USAN: imipramine type compounds)

 

(a)

saturated dibenzazepine:

 

azipramine (36), carpipramine (16), cianopramine (47), ciclopramine (29), clocapramine (28), clomipramine (17), depramine (31), desipramine (13), imipramine (8), ketimipramine (17), lofepramine (24), lopramine (24) (replaced by lofepramine (34)), metapramine (34), mosapramine (64), pumaprazole (76), quinupramine (32), tampramine (54), tienopramine (38), trimipramine (13), imipraminoxide (36)

(c)

unsaturated dibenzazepine:

 

carbamazepine (15), homopipramol (20), opipramol (15)

TRS 581

 
 

USAN

-prazole

antiulcer, benzimidazole derivatives

J.0.0.0

(USAN: antiulcerative benzimidazole derivatives)

 

(a)

cinprazole (34), disuprazole (56), esaprazole (45), esomeprazole (79), fuprazole (39), ilaprazole (86), lansoprazole (60), leminoprazole (68), nepaprazole (74), nilprazole (37), omeprazole (46), pantoprazole (62), picoprazole (46), pumaprazole (76), rabeprazole (69), saviprazole (62), tenatoprazole (80), timoprazole (35), ufiprazole (58)

-piprazole

psychotropics, phenylpiperazine derivatives

C.0.0.0

(a)

aripiprazole (75), dapiprazole (45), elopiprazole (70), enpiprazole (24), lorpiprazole (60), mepiprazole (24), sonepiprazole (80) tolpiprazole (25)

(b)

dapiprazole (see above)

 

USAN

pred

prednisone and prednisolone derivatives

Q.3.3.0

(USAN: pred-; -pred- or -pred)

 

(a)

chloroprednisone (12), cloprednol (31), difluprednate (21), domoprednate (47), fluprednidene (19), fluprednisolone (13), halopredone (36), isoflupredone (36), isoprednidene (24), loteprednol (64), mazipredone (32), meprednisone (15), methylprednisolone (8), methylprednisolone aceponate (52), methylprednisolone suleptanate (56), oxisopred (29), prednazate (16), prednazoline (22), prednicarbate (44), prednimustine (31), prednisolamate (13), prednisolone (6), prednisolone steaglate (16), prednisone (6), prednylidene (13), tipredane (54)

(c)

-methasone or -metasone: alclometasone (41), amelometasone (74), beclometasone (17), betamethasone (11), betamethasone acibutate (26), cormetasone (29), desoximetasone (20), dexamethasone (8), dexamethasone acefurate (57), flumetasone (13), halometasone (41), icometasone enbutate (70), mometasone (56), paramethasone (12)

 

-betasol: clobetasol (26), doxibetasol (26), ulobetasol (54)

 

(USAN: steroids (not prednisolone derivatives))

Q.3.0.0

-olone: clocortolone (16), descinolone (17), diflucortolone (18), fluclorolone acetonide (22), fluocinolone acetonide (11), fluocortolone (15), fluorometholone (8), fluperolone (13), ganaxolone (76), halocortolone (31), rimexolone (38), triamcinolone (8), triamcinolone benetonide (36), triamcinolone furetonide (36), triamcinolone hexacetonide (15)

 

clobetasone (26), cloticasone (52), deprodone (20), dichlorisone (10), diflorasone (30), flunisolide (11), fluticasone (52), meclorisone (40), timobesone (51)

-olone

steroids other than prednisolone derivatives

A.1.2.0

general anesthetics, pregnanes: alfadolone (27), alfaxalone (27), minaxolone (39), renanolone (8)

H.2.0.0

anti-arrhythmic: amafolone (40), edifolone (56)

L.6.0.0

cytostatics - sex hormones: drostanolone (13), trestolone (25)

Q.2.3.0

androgens: androstanolone (4), drostanolone (13), mesabolone (29), mestanolone (10), mesterolone (15), metenolone (12), metribolone (17), nandrolonoe (22), norethandrolone (6), oxabolone cipionate (14), oxandrolone (12), oxymetholone (11), quinbolone (14), rosterolone (59), stenbolone (17), tibolone (22), trenbolone (24)

J.0.0.0

glycyrrhetic acid derivatives: carbenoxolone (15), cicloxolone (33), cinoxolone (33), deloxolone (51), enoxolone (15), roxolonium metilsulfate (33)

Q.2.3.1

oxendolone (42)

 

various non-steroidal compounds

 

citiolone (23) (hepato-bil.troubles), clorexolone (15) (diuretic), fenozolone (14) (psychotonic), tioxolone (16) (keratolytic), vistatolon (25) (antiviral)

TRS 581

 

-prenaline

see -terol

 

USAN

-pressin

vasoconstrictors, vasopressin derivatives

Q.1.2.0

(a)

argipressin (13), desmopressin (33), felypressin (13), lypressin (13), ornipressin (22),

 

terlipressin (46), vasopressin injection (16)

TRS 581

 
 

BAN, USAN

-pride (x)

sulpiride derivatives

C.0.0.0

 

J.1.0.0

(a)

C.0.0.0: alizapride (43), alpiropride (49), amisulpride (44), batanopride (61), broclepride (43), cisapride (49), dazopride (50), denipride (58), etacepride (52), eticlopride (52), flubepride (35), nemonapride (63) (previously emonapride (61)), peralopride (43), prosulpride (43), prucalopride (78), sulmepride (43), sultopride (26), sulverapride (44), veralipride (43)

 

J.1.0.0: alepride (40), bromopride (27), cinitapride (41), cipropride (41), clebopride (32), dobupride (57), irolapride (55), isosulpride (36), itopride (66), lintopride (65), lirexapride (74), lorapride (44), mezacopride (56), mosapride (66), pancopride (62), raclopride (52), remoxipride (49), renzapride (60), tiapride (28), ticalopride (83), tinisulpride (44), trazolopride (51), tropapride (48), zacopride (55)

 

K.0.0.0: cloxacepride (42)

 

U.1.1.0/C.0.0.0: iolopride (123I) (73)

(b)

glimepride (66)

(c)

C.0.0.0: levosulpiride (63), sulpiride (18)

 

J.1.0.0: metoclopramide (17)

 

BAN, USAN

-pril (x)

angiotensin-converting enzyme inhibitors

H.3.0.0

(BAN: inhibitors of angiotensin-converting enzyme)

 

(USAN: antihypertensive agents (captopril type))

(a)

alacepril (50), benazepril (58), captopril (39), ceronapril (64), cilazapril (53), delapril (54), enalapril (46), fosinopril (56), idrapril (66), imidapril (60), indolapril (50), libenzapril (58), lisinopril (50), moexipril (60), moveltipril (58), orbutopril (57), pentopril (53), perindopril (53), pivopril (52), quinapril (54), ramipril (52), rentiapril (55), spirapril (56), temocapril (64), trandolapril (53), utibapril (63), zabicipril (58), zofenopril (51)

-prilat (x)

 

(a)

benazeprilat (58), cilazaprilat (54), enalaprilat (50), fosinoprilat (62), imidaprilat (71), moexiprilat (67), perindoprilat (56), quinaprilat (60), ramiprilat (53), spiraprilat (60), temocaprilat (78), trandolaprilat (60), utibaprilat (65), zabiciprilat (64), zofenoprilat (63)

 

USAN

-prim

antibacterials, trimethoprim derivatives

S.5.5.0

(a)

aditoprim (49), baquiloprim (56), brodimoprim (44), epiroprim (44), metioprim (42), ormetoprim (21), tetroxoprim (33), trimethoprim (11), vaneprim (48)

(c)

diaveridine (18)

 

BAN, USAN

-profen (x)

anti-inflammatory agents, ibuprofen derivatives

A.4.2.0

(USAN: anti-inflammatory or analgesic substances (ibuprofen type))

 

(a)

alminoprofen (40), araprofen (65), atliprofen (74), bakeprofen (61), benoxaprofen (34), bermoprofen (57), bifeprofen (57), carprofen (35), cicloprofen (32), cliprofen (32), dexibuprofen (61), dexindoprofen (49), dexketoprofen (70), esflurbiprofen (56), fenoprofen (26), flunoxaprofen (44), fluprofen (18), flurbiprofen (28), frabuprofen (51), furaprofen (42), furcloprofen (44), hexaprofen (30), ibuprofen (16), indoprofen (32), isoprofen (40), ketoprofen (28), lobuprofen (53), lonaprofen (44), losmiprofen (61), loxoprofen (50), mabuprofen (64), mexoprofen (33), miroprofen (44), odalprofen (66), pelubiprofen (76), piketoprofen (40), pirprofen (32), pranoprofen (38), suprofen (31), tazeprofen (50), tetriprofen (29), tilnoprofen arbamel (74), tioxaprofen (39), vedaprofen (72), ximoprofen (37), zaltoprofen (64), zoliprofen (55)

(b)

aprofene (12) (antispasm. coron. vasodil.), diprofene (12) (antispasm. blood vessels)

(c)

brofezil (31), protizinic acid (27), tiaprofenic acid (30)

TRS 581

 
 

BAN, USAN

prost (x)

prostaglandins

Q.0.0.0

(USAN: -prost- or -prost: prostaglandin derivatives)

(a)

alfaprostol (45), alprostadil (39), ataprost (62), beraprost (59), bimatoprost (85), butaprost (55), carboprost (36), cicaprost (54), ciprostene (51), clinprost (68), cloprostenol (33), delprostenate (42), dimoxaprost (52), dinoprost (26), dinoprostone (26), doxaprost (34), ecraprost (83), eganoprost (84), enisoprost (50), epoprostenol (44), eptaloprost (56), etiproston (46), fenprostalene (42), flunoprost (53), fluprostenol (33), froxiprost (55), gemeprost (42), iloprost (48) (originally ciloprost (46)), lanproston (72), latanoprost (67), limaprost (56), lubiprostone (87), luprostiol (44), meteneprost (45), misoprostol (47), naxaprostene (58), nileprost (45), nocloprost (51), oxoprostol (44), penprostene (37), pimilprost (71), piriprost (51), prostalene (34), remiprostil (65), rosaprostol (48), sulprostone (37), taprostene (58), tiaprost (41), tilsuprost (51), tiprostanide (48), travoprost (80), treprostinil (87), unoprostone (66), vapiprost (58), viprostol (53)

-prostil

prostaglandins, anti-ulcer

(a)

arbaprostil (35), deprostil (32), enprostil (50), mexiprostil (52), ornoprostil (56), rioprostil (49), spiriprostil (63), trimoprostil (49)

TRS 581

 

-quine (d)

quinoline derivatives (deleted from General Principles in List 28 prop. INN)

quin

 
 

(a)

antimalarial: amodiaquine (1), amopyroquine (8), bulaquine (82), chloroquine (4), hydroxychloroquine (8), mefloquine (33), moxipraquine (26), pamaquine (4), pentaquine (4), primaquine (1), quinocide (34), tafenoquine (80), tebuquine (49)

 

amebicide: clamoxyquine (16), mebiquine (29) (gastrointest. antiseptic), benzoxiquine (18) (antiseptic), cletoquine (20) (anti-inflammatory), cloxiquine (30) (antiseptic), debrisoquine (15) (hypotensive agent), esproquine (31) (cardiovascular agent), flumequine (34) (antibacterial), guanisoquine (15) (hypotensive agent), nifuroquine (36), oxamniquine (28) (schistosomacide)

(c)

antirheumat., antigout (antimalarial): acequinoline (22), cinchophen (1), neocinchophen (1), oxycinchophen (6)

 

antibact.: actinoquinol (15), aminoquinuride (45), broquinaldol (17), broxaldine (12), chlorquinaldol (1), clioquinol (16), dequalinium chloride (8), diiodohydroxyquinoline (1), laurolinium acetate (12), nitroxoline (15), quindecamine (15), tilbroquinol (45), tiliquinol (45)

 

antifungal: hedaquinium chloride (8)

 

anthelmintic: pyrvinium chloride (6)

 

treatment of leishmaniasis etc: aminoquinol (22), sitamaquine (80)

 

amebicide: cloquinate (11), dehydroemetine (15), quinfamide (40)

 

antiproteus: oxolinic acid (15)

 

coccidiostat: amquinate (21), buquinolate (16), ciproquinate (22), decoquinate (20), nequinate (22), proquinolate (17), quindoxin (26) (growth promoter for pigs and poultry)

 

growth promoter, bactericide: cinoquidox (40), olaquindox (31) (quinoxaline derivative)

 

antiviral: famotine (23), memotine (22)

 

antihypertensive: amiquinsin (17), leniquinsin (18), peraquinsin (29) (quinazolinone derivative), trethinium tosilate (14), quinuclium bromide (40)

 

heart failure: buquineran (40)

 

diuretic: quincarbate (31)

 

vasodilator, treatment of cerebrovascular insuff.: viquidil (25)

 

curarizing agent: dimethyltubocurarinium chloride (1), laudexium metilsulfate (4), tubocurarine chloride (1)

 

anti-cholinergic: toquizine (17), tiquizium bromide (47)

 

antispasm. muscle relaxant: dimoxyline (1), drotaverine (17), ethaverine (4), flucarbril (14), niceverine (15), octaverine (18), quinetalate (16)

 

bronchodilator: quinprenaline (17), tretoquinol (21), (bronchial asthma)

 

oxytocic: quipazine (17)

 

analgesic: glafenine (15), metofoline (12)

 

local anaesthetic: cinchocaine (1), euprocin (22), quinisocaine (4)

 

antituss.: iquindamine (34), noscapine (7)

 

diagnostic aid: quinaldine blue (17)

 

antihist.: pirquinozol (43), tritoqualine (14)

 

antihyperlipidemic: climiqualine (33) (isoquin. der.)

 

anti-ulcer: isotiquimide (49), tiquinamide (35)

 

BAN, USAN

-racetam

amide type nootrope agents, piracetam derivatives

B.1.0.0

(BAN: substances of the piracetam group)

 

(USAN: nootropic substances (piracetam type))

 

(a)

aloracetam (62), aniracetam (44), cebaracetam (66), coluracetam (86), dimiracetam (68), doliracetam (53), dupracetam (38), etiracetam (40), fasoracetam (78), imuracetam (42), levetiracetam (62), molracetam (55), nebracetam (59), nefiracetam (64), nicoracetam (63), oxiracetam (43), piracetam (22), pramiracetam (46), rolziracetam (54)

 

related: tenilsetam (51)

 

BAN, USAN

-relin (x)

prehormones or hormone-release stimulating peptides

Q.0.0.0

(BAN: hypophyseal hormone release-stimulating peptides)

(a)

LHRH-release-stimulating peptides: avorelin (74), buserelin (36), deslorelin (61), gonadorelin (32), goserelin (55), histrelin (53), leuprorelin (47), lutrelin (51), nafarelin (50), triptorelin (56)

-morelin

growth hormone release-stimulating peptides: capromorelin (83), dumorelin (59), examorelin (72), ipamorelin (78), pralmorelin (77), rismorelin (74), sermorelin (56), somatorelin (57), tabimorelin (80)

-tirelin

thyrotropin releasing hormone analogues:

(a)

azetirelin (60), fertirelin (42), montirelin (58), orotirelin (58), posatirelin (60), protirelin (31), taltirelin (75)

(a)

other: corticorelin (64)

TRS 581

 
 

USAN

-relix

hormone-release inhibiting peptides

(a)

abarelix (78), cetrorelix (64), degarelix (86), detirelix (56), ganirelix (65), iturelix (79), prazarelix (81), ramorelix (68), teverelix (71)

 

USAN

-renone

aldosterone antagonists, spironolactone derivates

N.1.8.0

(USAN: aldosterone antagonists (spironolactone type))

 

(a)

canrenoic acid (20) and potassium canrenoate (20), canrenone (20), dicirenone (50), drospirenone (63), eplerenone (77), mespirenone (51), spirorenone (45)

(b)

bromchlorenone (12) (antifungal), menatetrenone (28) (antihemor-rhagic), teprenone (50), ubidecarenone (48) (in congestive heart failure)

(c)

oxprenoate potassium (53), prorenoate potassium (32), spironolactone (11), spiroxasone (14)

 

USAN

retin

retinol derivatives

P.1.0.0

(USAN: -retin-)

 

(a)

acitretin (56) (previously etretin (51)), alitretinoin (80), doretinel (60), etretinate (41), fenretinide (51), isotretinoin (41), motretinide (38), pelretin (60), retinol (18), tretinoin (25), tretinoin tocoferil (66)

(b)

noretynodrel (13), secretin (1), trethinium tosilate (14)

 

USAN

-ribine

ribofuranyl-derivatives of the "pyrazofurin" type

L.0.0.0./S.5.3.0

(a)

azaribine (19), cladribine (68), isatoribine (83), loxoribine (64), mizoribine (46), triciribine (46)

(c)

pirazofurin (31), ribavirin (31), riboprine (20), tiazofurine (48)

 

related: benaxibine (50)

 

USAN

rifa-

antibiotics, rifamycin derivatives

 

S.6.4.0

 

(a)

rifabutin (52), rifalazil (78), rifametane (61), rifamexil (67), rifamide (15), rifampicin (17), rifamycin (13), rifapentine (43), rifaximin (49) (previously rifaxidine (48))

 

USAN

-rinone

cardiac stimulants, amrinone derivatives

H.1.0.0

(USAN: cardiotonic agents (amrinone type))

 

(a)

amrinone (38), bemarinone (57), medorinone (54), milrinone (50), nanterinone (60), olprinone (70), pelrinone (53), saterinone (56), toborinone (72), vesnarinone (57)

(b)

gestrinone (39), indacrinone (51), taziprinone (48)

-rizine

see -izine

 

USAN

-rozole

aromatase inhibitors, imidazole-triazole derivatives

L.0.0.0

 

anastrozole (72), fadrozole (64), finrozole (81), letrozole (70), liarozole (64), vorozole (64)

 

USAN

-rubicin

antineoplastic antibiotics, daunorubicin derivatives

L.5.0.0

(USAN: antineoplastic antibiotics (daunorubicin type))

 

(a)

aclarubicin (44), amrubicin (65), carubicin (40), daunorubicin (20), detorubicin (41), doxorubicin (25), epirubicin (48) (originally pidorubicin (47)), esorubicin (47), galarubicin (80), idarubicin (47), ladirubicin (83), leurubicin (64), medorubicin (47), nemorubicin (71), pirarubicin (55), rodorubicin (54), valrubicin (79), zorubicin (39)

 

USAN

sal

salicylic acid derivatives

 

(USAN: -sal-; -sal; or sal-)

 

(a)

sal-

analgesic anti-inflammatory A.4.2.0

 

choline salicylate (15), imidazole salicylate (51), salacetamide (1), salcolex (23), saletamide (20), salfluverine (29), salicylamide (1), salnacedin (73), salprotoside (31), salsalate (28), salverine (15)

 

various

 

salantel (29) (anthelmintic), salinazid (8) (antituberc.)

 

-sal

analgesic anti-inflammatory A.4.2.0

 

detanosal (23), diflunisal (33), fendosal (35), flufenisal (22), fosfosal (37), guacetisal (40), guaimesal (50), parcetasal (65), pranosal (24), sulprosal (36), tenosal (63)

 

antithrombotic

 

flufosal (42)

 

various: antituberc.

 

fenamisal (15), thiomersal (1) (disinfect.), triflusal (37) (antithrombotic)

 

-sal-

analgesic anti-inflammatory A.4.2.0

 

acetaminosalol (1), acetylsalicylic acid (IP), carbasalate calcium (27), carsalam (13), etersalate (50), etosalamide (14), parsalmide (32), talosalate (43)

 

various

 

amotosalen (85), calcium benzamidosalicylate (10), homosalate (28) (sunscreen agent), lasalocid (30) (antibiotic. vet.), mersalyl (4) (mercurial diuretic), octisalate (83) (sunscreen), osalmid (15) (choleretic), xenysalate (12) (antiseborrheic)

 

salazo-

phenylazosalicylic acid derivatives antibact. S.5.1.0

 

salazodine (22), salazosulfadimidine (11), salazosulfamide (1), salazosulfathiazole (1)

 

-salazine/-salazide

 

dersalazine (86), mesalazine (52), olsalazine (52), sulfasalazine (55), balsalazide (48), ipsalazide (48)

 

-salan

brominated salicylamide derivatives disinfect. S.2.1.0

 

bensalan (18), dibromsalan (14), flusalan (16), fursalan (18), metabromsalan (16), tiosalan (18), tribromsalan (14)

(b)

non-salicylic acid derivatives

 

macrosalb (99mTc) (33), trioxysalen (16) (pigmenting agent)

 

bronchodil.

 

levosalbutamol (78), salbutamol (20), salmefamol (23)

(c)

analgesic, anti-inflammatory A.4.2.0

 

aloxiprin (13), anilamate (13), benorilate (21), brosotamide (29), cresotamide (28), dibusadol (24), dipyrocetyl (6), ethenzamide (10), fenamifuril (16), hydroxytoluic acid (17), sodium gentisate (1), sodium glucaspaldrate (17)

 

various

 

4-aminosalicylates of the -caine series D.1.0.0: ambucaine (6), hydroxyprocaine (1), hydroxytetracaine (1), propoxycaine (4)

 

antihypertensives H.3.0.0

 

labetalol (35)

 

antitussives K.1.0.0

 

alloclamide (16), flualamide (20)

 

saluretics N.1.2.0

 

xipamide (22) (sulfamoyl deriv.),

 

mercurial diuretics N.1.3.0

 

mercuderamide (1)

 

anthelmintics S.3.1.0

 

bromoxanide (31), clioxanide (19), niclosamide (13), rafoxanide (24)

 

closantel (36), flurantel (25), resorantel (23)

 

antifungals S.4.0.0

 

buclosamide (16), exalamide (37), pentalamide (13)

 

See also Pharm S/Nom 557

 

USAN

-sartan

angiotensin II receptor antagonists, antihypertensive (non-peptidic)

H.3.0.0

 
 

abitesartan (73), candesartan (71), elisartan (72), embusartan (78), eprosartan (71), forasartan (74), irbesartan (71), losartan (66), milfasartan (76), olmesartan (80), pomisartan (73), pratosartan (85), ripisartan (73), saprisartan (72), tasosartan (72), telmisartan (70), valsartan (68), zolasartan (70)

 

USAN

-semide

diuretics, furosemide derivatives

N.1.1.0

(a)

azosemide (35), furosemide (14), galosemide (33), torasemide (35)

 

USAN

-serpine (d)

derivatives of Rauwolfia alkaloids

E.5.4.0

 

(a)

bietaserpine (14), mefeserpine (15), reserpine (4)

(c)

chloroserpidine (11), deserpidine (6), methoserpidine (11), metoserpate (20), rescimetol (44), rescinnamine (6), syrosingopine (10)

TRS 581

 
 

USAN

-setron

serotonin receptor antagonists (5-HT3) not fitting into other establishedgroups of serotonin receptor antagonists

 

(BAN: serotonin receptor antagonists (5HT3) used as antihyper-tensives)

   

(a)

alosetron (66), azasetron (68), bemesetron (64), cilansetron (68), dolasetron (65), fabesetron (74), galdansetron (72), granisetron (59), indisetron (76), itasetron (68), lerisetron (69), lurosetron (69), mirisetron (72), ondansetron (59), palonosetron (74), ramosetron (70), ricasetron (70), tropisetron (62), zatosetron (64)

 

USAN

som-

growth hormone derivatives

Q.0.0.0

 

(a)

somagrebove (63), somalapor (62), somatosalm (69), somatrem (54), somatropin (56), somavubove (63), somenopor (62), somfasepor (66), sometribove (54), sometripor (55), somidobove (58)

(b)

somatorelin (57), somantadine (51), somatostatin (46)

 

USAN

-spirone

anxiolytics, buspirone derivatives

C.1.0.0

(a)

alnespirone (70), binospirone (65), buspirone (30), enilospirone (52), perospirone (71), revospirone (61), tandospirone (60), tiospirone (57), umespirone (60), zalospirone (64)

(c)

eptapirone (82), gepirone (54), ipsapirone (54)

 

BAN, USAN

-stat- or-stat

enzyme inhibitors

 

(BAN: -stat: enzyme inhibitors)

-castat

dopamine -hydroxylase inhibitors

 

nepicastat (78)

-elestat

elastase inhibitors

 

sivelestat (78)

-listat

pancreatic lipase inhibitors

(a)

orlistat (66)

-mastat

matrix metalloproteinase inhibitors

(a)

batimastat (70), cipemastat (81), ilomastat (73), marimastat (75), prinomastat (82), solimastat (80), tanomastat (82)

-restat or-restat-

aldose reductase inhibitors

M.5.0.0

 

(a)

alrestatin (37), epalrestat (55), fidarestat (78), imirestat (59), lidorestat (87), minalrestat (76), ponalrestat (58), risarestat (82), tanomastat (82), tolrestat (51), zenarestat (64), zopalrestat (64)

-vastatin

antihyperlipidaemic substances, HMG CoA reductase inhibitors

 

H.4.0.0

 

(a)

atorvastatin (71), bervastatin (72), cerivastatin (74), crilva-statin (63), dalvastatin (64), fluvastatin (62), glenvastatin (70), lovastatin (57), mevastatin (44), pitavastatin (83) (replaces itavastatin (80)), pravastatin (57), rosuvastatin (83), simvastatin (58), tenivastatin (85)

 
 

proteolytic enzyme inhibitors: aloxistatin (57), ulinastatin (56); camostat (46), nafamostat (53), patamostat (69), sepimostat (68)

 

various:

azalanstat (73):

lanosterol 14α -demethylase inhibitor

 

febuxostat (85):

xanthine oxidase and xanthine dehydrogenase inhibitor

 

benurestat (31):

urease inhibitor

 

cilastatin (50):

renal dehydropeptidase inhibitor

 

miglustat (85):

glucosyltransferase inhibitor

 

nystatin (6):

antifungal antibiotic

 

pentostatin (38):

vidarabin activity potentiator; inhibitor of enzymatic deaminative metabolism

 

pepstatin (28):

pepsin inhibitor

 

somatostatin (43):

growth hormone release inhibiting factor

 

tendamistat (44):

amylase inhibitor

 

vistatolon (25):

antiviral antibiotic

 

zinostatin (40):

antineoplastic

 

zinostatin stimalamer (74)

 
 

BAN

-steine

mucolytics, other than bromhexine derivatives

 

K.0.0.0

(BAN: substances of the acetylcysteine group)

 

(a)

acetylcysteine (13), bencisteine (30), carbocisteine (34), cartasteine (72), dacisteine (49), danosteine (53), erdosteine (56), fudosteine (77), guaisteine (57), isalsteine (63), letosteine (38), mecysteine (13), midesteine (63), moguisteine (61), nesosteine (52), omonasteine (40), prenisteine (42), salmisteine (58), taurosteine (63), telmesteine (63)

 
 

USAN

-ster-

androgens/anabolic steroids

 

Q.2.3.1

 

(a)

-testosterone: cloxotestosterone (12), methyltestosterone (4), testosterone (4), testosterone ketolaurate (16)

 
 

-sterone: bolasterone (13), fluoxymesterone (6), oxymesterone (12), prasterone (23), tiomesterone (14)

 
 

-ster-: mesterolone (15), penmesterol (14), rosterolone (59)

(b)

progestational steroids

 

-gesterone: dydrogesterone (12), haloprogesterone (11), hydroxyprogesterone (8), medroxyprogesterone (10), norgesterone (14), progesterone (4)

 

-sterone: dimethisterone (8), ethisterone (4), norethisterone (6), norvinisterone (10)

various:

-sterone: aldosterone (6) (corticosteroid), calusterone (23) (antineoplastic)

 

-sterol: azacosterol (16) (hypocholesterolemic), dihydrotachy-sterol (1) (antihypoparathyroid), iodocholesterol (131I) (39)

 

ster: nisterime (38) (contragestational agent), stercuronium iodide (21) (neuromuscular blocking agent)

-(a)steride

(USAN: testosterone reductase inhibitors) - antineoplastic

 

bexlosteride (81), dutasteride (78), epristeride (69), finasteride (62), izonsteride (81), lapisteride (85), turosteride (67)

-stigmine (d)

acetylcholinesterase inhibitors

E.1.2.0

 

(a)

distigmine bromide (16), eptastigmine (62), ganstigmine (81), neostigmine bromide (4), pyridostigmine bromide (6), quilostigmine (76), rivastigmine (77), terestigmine (77)

(c)

eseridine (53)

 

USAN

-stim

colony stimulating factors

I.5.0.0

 
 

ancestim (79) (cell growth factor), garnocestim (85) (immunomodulator), pegacaristim (80) (megakaryocyte growth factor)

-distim

combination of two different types of colony stimulating factors

(a)

milodistim (74), leridistim (80)

-grastim

granulocyte colony stimulating factor (G-CSF) type substances

(a)

filgrastim (64), lenograstim (64), nartograstim (66), pegfilgrastim (85), pegnartograstim (80)

-gramostim

granulocyte macrophage colony stimulating factor (GM-CSF) types substances

(a)

ecogramostim (62), molgramostim (64), regramostim (64), sargramostim (66)

-mostim

macrophage stimulating factors (M-CSF) type substances

(a)

cilmostim (71), mirimostim (65)

-plestim

interleukin-3 analogues and derivatives

 

daniplestim (76), muplestim (72)

 

BAN, USAN

sulfa-

anti-infectives, sulfonamides

S.5.1.0

(BAN: sulpha-)

 

(USAN: antimicrobial sulfonamides)

 

(a)

sulfabenz (17), sulfabenzamide (27), sulfacarbamide (12), sulfacecole (30), sulfacetamide (1), sulfachlorpyridazine (10), sulfachrysoidine (1), sulfacitine (23), sulfaclomide (17), sulfaclorazole (25), sulfaclozine (25), sulfadiasulfone sodium (1), sulfadiazine (4), sulfadiazine sodium (4), sulfadicramide (4), sulfadimethoxine (10), sulfadimidine (1), sulfadoxine (20), sulfaethidole (8), sulfafurazole (1), sulfaguanidine (4), sulfaguanole (23), sulfalene (12), sulfaloxic acid (15), sulfamazone (40), sulfamerazine (4), sulfamerazine sodium (4), sulfamethizole (1), sulfamethoxazole (14), sulfamethoxypyridazine (8), sulfametomidine (12), sulfametoxydiazine (17), sulfametrole (31), sulfamonomethoxine (11), sulfamoxole (12), sulfanilamide (4), sulfanitran (15), sulfaperin (14), sulfaphenazole (10), sulfaproxyline (4), sulfapyrazole (18), sulfapyridine (1), sulfaquinoxaline (46), sulfasalazine (55), sulfasomizole (10), sulfasuccinamide (41), sulfasymazine (12), sulfathiazole (4), sulfathiourea (1), sulfatolamide (10), sulfatroxazole (29), sulfatrozole (24)

(b)

sulfarsphenamine (4)

(c)

benzylsulfamide (1), glucosulfamide (1), maleylsulfathiazole (1), mesulfamide (41), nitrosulfathiazole (1), phthalylsulfamethizole (6), phthalylsulfathiazole (1), salazodine (22), salazosulfa-dimidine (11), salazosulfamide (1), salazosulfathiazole (1), stearylsulfamide (1), succinylsulfathiazole (4), sulfisomidine (1), vanyldisulfamide (1), mafenide (1) (sulfonamide, but not sulfanilamide)

TRS 581

 
 

USAN

-sulfan

antineoplastic, alkylating agents, methanesulfonates

L.2.0.0

(a)

busulfan (6), improsulfan (35), mannosulfan (24), piposulfan (15), ritrosulfan (33), treosulfan (26)

TRS 581

 

-tant

neurokinin (tachykinin) receptor antagonists

-pitant

neurokinin NK1 (substance P) receptor antagonist

(a)

aprepitant (84), dapitant (74), ezlopitant (82), figopitant (82), vofopitant (82), lanepitant (77), nolpitantium besilate (75)

-dutant

neurokinin NK2 receptor antagonist

 

nepadutant (78), saredutant (75)

-nertant

neurotensin antagonist

 

reminertant (85)

-netant

neurokinin NK3 receptor antagonist

(a)

osanetant (74), talnetant (81)

-tecan

antineoplastics, topoisomerase I inhibitors

L.0.0.0

(USAN: anti-neoplastics (camptothecine derivatives))

 

afeletecan (85), diflomotecan (84), exatecan (81), gimatecan (86), irinotecan (64), lurtotecan (74), mureletecan (85), rubitecan (82), topotecan (65)

 

USAN

-tepa

antineoplastics, thiotepa derivatives

L.2.0.0

(USAN: antineoplastic thiotepa derivatives)

 

(a)

azatepa (12), pumitepa (48), thiotepa (10)

-tepine

see -pine

 

USAN

-teplase

tissue type plasminogen activators, see -ase item VI

 

BAN, USAN

-terol (x)

bronchodilators, phenethylamine derivatives

(previously-prenaline or-terenol unofficial)

(USAN: bronchodilators (phenethylamine derivatives))

 

(a)

amiterol (26), bambuterol (49), bitolterol (34), broxaterol (51), carbuterol (29), cimaterol (54), clenbuterol (28), colterol (36), difeterol (36), divabuterol (51), etanterol (53),

E.4.0.0

fenoterol (26), formoterol (44), imoxiterol (52), mabuterol (46), naminterol (53), nardeterol (62), picumeterol (64), pirbuterol (30), procaterol (37), reproterol (30), rimiterol (26), salmeterol (55), sulfonterol (31), tobuterol (45), tulobuterol (40), zilpaterol (60), zinterol (38)

 

cardiac stimulants:

 

metaterol (43), prenalterol (38), xamoterol (48); clorprenaline (17), hexoprenaline (21), isoprenaline (1), levisoprenaline (10), metiprenaline (24), orciprenaline (14), quinprenaline (17)

 

deterenol (25), soterenol (20)

(b)

azacosterol (16), dihydrotachysterol (1), penmesterol (14)

(c)

dioxethedrine (6), isoetarine (13), methoxyphenamine (1), pseudoephedrine (11), salbutamol (20), salmefamol (23), terbutaline (22)

TRS 581

 

-terone

antiandrogens

(Q.2.3.1)

 

(a)

abiraterone (74), benorterone (15), cyproterone (16), delanterone (42), inocoterone (54), osaterone (68), zanoterone (67)

(b)

oxendolone (42)

(c)

clometerone (15) (anti-estrogen)

 

USAN

-tiazem

calcium channel blockers, diltiazem derivatives

F.2.1.0

 

clentiazem (61), diltiazem (30), iprotiazem (56), nictiazem (54), siratiazem (68)

 

USAN

-tide

peptides and glycopeptides (for special groups of peptides see -actide, -pressin, -relin, -tocin)

 

analgesic: leconotide (86), ziconotide (78)

 

angiogenesis inhibitor: cilengitide (81)

 

antibiotic: nosiheptide (35)

 

antidepressant: nemifitide (87)

 

antidiabetic: amlintide (76), liraglutide (87), seglitide (57), pramlintide (74)

 

antidiarrhoeal: lagatide (75)

 

antithrombotic: eptifibatide (78)

 

angiotensin convers. inhibitor: teprotide (36)

 

atrial natriuretic factor type substance: anaritide (57), neseritide (80), ularitide (69)

 

cardiac stimulant: carperitide (65)

 

diagnostic: betiatide (58), bibapcitide (78), ceruletide (34), depreotide (80), mertiatide (60), pendetide (70), technetium (99mTc) apcitide (78), teriparatide (50)

 

gastro-intestinal bleeding/antineoplastic: edotreotide (84), ilatreotide (66), lanreotide (64), octreotide (52), pentetreotide (66), vapreotide (62)

 

gut motility increasing: ociltide (52)

 

immunomodulator: almurtide (74), goralatide (72), murabutide (49), pentigetide (60), pimelautide (53), prezatide copper acetate (67), romurtide (61), tabilautide (60), temurtide (60), tiplimotide (82)

 

neuromodulator: ebiratide (56)

 

peptic ulcer: sulglicotide (29), triletide (50)

 

pulmonary surfactant: lusupultide (80), sinapultide (78)

 

sedative: emideltide (70)

 

treatment of Parkinson's disease: doreptide (58), pareptide (38)

(b)

defibrotide (44) (nucleotide), diamfenetide (28) (fasciolicide), diclometide (19) (behaviour modificator), fludroxycortide (12), glisentide (58)

 

BAN, USAN

-tidine (x)

histamine-H2-receptor antagonists, cimetidine derivatives

G.2.0.0

(BAN: H2-receptor antagonists of the cimetidine group)

 

(USAN: H2-receptor antagonists (cimetidine type))

 

(a)

bisfentidine (57), cimetidine (33), dalcotidine (76), donetidine (56), ebrotidine (57), etintidine (44), famotidine (48), lafutidine (70), lamtidine (48), lavoltidine (61) (previously loxtidine (48)), lupitidine (53), mifentidine (50), niperotidine (54), nizatidine (48), osutidine (76), oxmetidine (44), pibutidine (78), quisultidine (47) (replaced by quisultazine (51)), ramixotidine (55), ranitidine (41), roxatidine (54), sufotidine (54), tiotidine (44), tuvatidine (54), venritidine (67), zaltidine (54)

(b)

benzethidine (9), furethidine (9), guanethidine (11), hexetidine (6), hydroxypethidine (5), pethidine (4), propinetidine (12)

 

azacitidine (40) (antineoplastic)

(c)

metiamide (30)

-tirelin

see -relin

-tiline

see -triptyline

 

USAN

-tizide

diuretics, chlorothiazide derivatives

N.1.2.1

(USAN: thiazide: diuretics (thiazide derivatives))

 

(a)

altizide (13), bemetizide (27), butizide (13), carmetizide (30), epitizide (13), hydrobentizide (14), mebutizide (15), paraflutizide (16), penflutizide (29), sumetizide (20)

(c)

bendroflumethiazide (11), benzthiazide (10), chlorothiazide (8), cyclopenthiazide (12), cyclothiazide (12), disulfamide (11), ethiazide (14), flumethiazide (10), hydrochlorothiazide (10), hydroflumethiazide (10), methyclothiazide (11), polythiazide (12), teclothiazide (12), trichlormethiazide (11)

TRS 581

 
 

USAN

-tocin

oxytocin derivatives

Q.1.2.0

(a)

argiprestocin (13), aspartocin (11), carbetocin (45), cargutocin (35), demoxytocin (22), nacartocin (49), oxytocin (13)

 

USAN

-toin (d)

antiepileptics, hydantoin derivatives

A.3.1.1

(a)

albutoin (13), doxenitoin (31), ethotoin (6), fosphenytoin (62), mephenytoin (1), metetoin (12), phenytoin (4)

 

ropitoin (40) (H.2.0.0.)

(b)

clodantoin (13) (antifungal), nitrofurantoin (11) (antibact.)

TRS 581

 
 

USAN

-trexate (x)

folic acid analogues

L.4.0.0

(USAN: folic acid analogues used as antimetabolites)

 

(a)

edatrexate (61), ketotrexate (50), methotrexate (10), trimetrexate (46)

 

USAN

-tricin

antibiotics, polyene derivatives

S.6.2.0

 

(a)

mepartricin (34), partricin (27)

(b)

tyrothricin (1)

(c)

amphotericin B (10), candicidin (17), filipin (20), hachimycin (23), hamycin (17), levorin (15), mocimycin (28), natamycin (15), nystatin (6), pecilocin (16)

-triptan

serotonin (5HT1) receptor agonists, sumatriptan derivatives

(a)

almotriptan (76), avitriptan (76), donitriptan (82), eletriptan (74), frovatriptan (78), naratriptan (69), oxitriptan (39), rizatriptan (75), sumatriptan (59), zolmitriptan (74)

(c)

alniditan (72)

 

USAN

-triptyline

antidepressants, dibenzo[a,d]cycloheptane or cyclopheptene derivatives

C.3.2.0

(USAN: antidepressants (dibenzo[a,d]cycloheptane derivatives))

 

(a)

amitriptyline (11), butriptyline (16), cotriptyline (26), intriptyline (26), nortriptyline (12), octriptyline (33), protriptyline (14), amitriptylinoxide (36), demexiptiline (43), levoprotiline (56), noxiptiline (20), oxaprotiline (45), setiptiline (56)

(b)

oxitriptyline (21) (anticonvuls.)

(c)

hepzidine (15)

TRS 581

see also Pharm S/Nom 970

-troban

thromboxane A2-receptor antagonists; antithrombotic agents

I.2.1.0

 
 

argatroban (57), daltroban (57), domitroban (73), ifetroban (71), linotroban (69), mipitroban (73), ramatroban (73), sulotroban (55)

 

USAN

trop

atropine derivatives

E.2.0.0

(USAN: trop-; or -trop-)

 

(a)

parasympatholytic/anticholinergic: E.2.2.0:

 

tertiary amines:

 

atropine oxyde (12), benzatropine (4), decitropine (18), etybenzatropine (12), eucatropine (1), tropatepine (28), tropicamide (11), tropigline (8), tropodifene (18)

 

closely related:

 

esbatropate (65)

 

quaternary ammonium salts:

 

atropine methonitrate (4), butropium bromide (30), ciclotropium bromide (50), cimetropium bromide (51), flutropium bromide (50), homatropine methylbromide (1), ipratropium bromide (28), octatropine methylbromide (10), oxitropium bromide (36), phenactropinium chloride (8), ritropirronium bromide (33), sevitropium mesilate (56), sintropium bromide (47), sultroponium (18), tematropium metilsulfate (64), tiotropium bromide (67), tipetropium bromide (42), tropenziline bromide (11), xenytropium bromide (15)

 

various:

 

clobenztropine (13) (antihistaminic), cyheptropine (15) (antiar-rhythmic), deptropine (12) (antiasthmatic), revatropate (74) (bronchodilator), tropabazate (41) (tranquillizer), tropanserin (55), tropapride (48) (antipsychotic), tropirine (20) (respi-ratory disorders), tropisetron (62)

(b)

dextropropoxyphene (7), somatropin (56)

(c)

parasympatholytic/anticholinergic, tertiary amines:

 

poskine (8), prampine (11), tigloidin (14)

 

various:

 

zepastine (26) (antihistaminic)

-uplase

urokinase type plasminogen activator, see -ase item VII

-ur

see -uridine

 

USAN

-uracil

uracil derivatives used as thyroid antagonists and as antineoplastics

 

 

thyroid antagonists: iodothiouracil (1), methylthiouracil (1), propylthiouracil (1)

 

L.4.0.0: eniluracil (77), fluorouracil (13)

 

USAN

-uridine

uridine derivatives used as antiviral agents and as antineoplastics

S.5.3.0

 

L.4.0.0

 

L.4.0.0: broxuridine (30), doxifluridine (44)

 

related: carmofur (45), clanfenur (58), tegafur (41)

 

S.5.3.0: fialuridine (68), floxuridine (16), idoxuridine (17), navuridine (84), trifluridine (37)

-vudine

(USAN: vudine: antineoplastics; antivirals (zidovudine type))

 

related: alovudine (68), brivudine (59), clevudine (78), edoxudine (52), epervudine (61), fozivudine tidoxil (73), lamivudine (66), netivudine (72), sorivudine (64), stavudine (65), zidovudine (56)

-vastatin

see -stat-

 

BAN, USAN

-verine (x)

spasmolytics with a papaverine-like action

F.1.0.0

(USAN: spasmolytics having a papaverine-like action)

(a)

alverine (16), amifloverine (28), bietamiverine (6), butaverine (13), camiverine (29), caroverine (28), clofeverine (31), demelverine (17), denaverine (25), dexsecoverine (53), dicycloverine (6), dihexyverine (4), dipiproverine (10), diproteverine (51), drotaverine (17), elziverine (57), ethaverine (4), febuverine (27), fenoverine (28), floverine (28), heptaverine (16), ibuverine (21), idaverine (55), mebeverine (14), milverine (52), mofloverine (28), moxaverine (36), nafiverine (16), niceverine (15), octaverine (18), pargeverine (38), pentoxyverine (6), pramiverine (21), prenoverine (41), propiverine (45), rociverine (33), salfluverine (29), salverine (15), secoverine (38), temiverine (76), zardaverine (59)

 

fenpiverinium bromide (26), pinaverium bromide (32)

(b)

cinnamaverine (10) (anticholinergic, tert. amine), diaveridine (18)

(c)

spasmolytics chemically related to some of the above INN ending in -verine

 

butetamate (17), butinoline (14), camylofin (12), cinnamedrine (19), cyclandelate (8), difemerine (17), diisopromin (11), dimoxylin (1), fenpiprane (17), fenyramidol (12), metindizate (16), oxybutynin (13), papaveroline (29), pentapiperide (10), prozapine (14), triclazate (10), tropenziline bromide (11)

TRS 581

 
 

USAN

vin- and

vinca alkaloids

-vin- (x)

 
 

(USAN: vin-; or -vin-)

(a)

B.1.0.0 stim. of cerebrovasc. circul.

 

apovincamine (48), brovincamine (42), vinburnine (45), vincamine (22), vincanol (37), vincantril (51), vinconate (47), vindeburnol (49), vinmegallate (59), vinpocetin (36), vinpoline (35), vintoperol (61)

 

L.5.0.0 cytostatic

 

vinblastine (12), vincristine (13), vindesine (35), vinepidine (50), vinflumine (76), vinformide (38), vinfosiltine (64), vinglycinate (16), vinleucinol (64), vinleur (13), vinorelbine (57), vinrosidine (13), vintriptol (51), vinzolidine (46)

(b)

barbiturates

 

vinbarbital (1), vinylbital (12)

 

others: vincofos (28) (phosphate, anthelmintic), vintiamol (16) (vit. B. deriv., antineuralgic)

 

BAN, USAN

vir

antivirals (undefined group)

S.5.3.0

(USAN: -vir; -vir; or vir-)

(a)

aciclovir (42), adefovir (72), alvircept sudotox (69), amdoxovir (85), amitivir (67), atevirdine (69), buciclovir (52), capravirine (83), cidofovir (72), dapivirine (86), delavirdine (71), denotivir (70), desciclovir (55), detiviciclovir (86), efavirenz (78), emivirine (82), enfuvirtide (85), enviradene (49), enviroxime (44), famciclovir (61), ganciclovir (56), litomeglovir (84), loviride (70), maribavir (80), nevirapine (66), omaciclovir (84), opaviraline (83), penciclovir (61), pirodavir (63), ribavirin (31), rociclovir (62), talviraline (75), tenofovir (82), tiviciclovir (86), tivirapine (74), tomeglovir (84), trovirdine (73), valaciclovir (69), valganciclovir (78), valomaciclovir (84), viroxime (49), zinviroxime (44)

-amivir

neuraminidase inhibitors: oseltamivir (80), peramivir (86), zanamivir (72)

-cavir

carbocyclic nucleosides: abacavir (76), entecavir (82), lobucavir (72)

-fovir

phosphonis acid derivatives: adefovir (72), cidofovir (72), tenofovir (82)

-gosivir

glucoside inhibitors: celgosivir (77)

-navir

HIV protease inhibitors: amprenavir (79), droxinavir (74), fosamprenavir (83), indinavir (74), lasinavir (76), lopinavir (80), mozenavir (84), nelfinavir (76), palinavir (74), ritonavir (74), saquinavir (69), telinavir (73), tipranavir (80)

 

USAN

-virsen

antisense oligonucleotides

(a)

afovirsen (70), fomivirsen (75), trecovirsen (77)

(b)

virginiamycin (18), viridofulvin (16)

(c)

avridine (50)

-vudine

see -uridine

-xanox

see -ox

K.0.0.0

 

-zafone

alozafone derivatives

C.1.0.0

(a)

alozafone (40), avizafone (64), ciprazafone (50), dinazafone (46), dulozafone (56), lorzafone (48), oxazafone (45), rilmazafone (55)

-zepine

see -pine

-zone

see -buzone

 

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The WHO Essential Medicines and Health Products Information Portal was designed and is maintained by Human Info NGO. Last updated: October 29, 2018