All prices are in US$. Prices are given both for a yearly adult dose and by unit.
For details on eligibility and offer restrictions for countries and institutions, please refer to tables 2d.
Products on the WHO list of Pilot Procurement, Quality and Sourcing Project: Access to HIV/AIDS drugs and diagnostics of acceptable quality (Sixth edition, 5th May 2003) are in bold and have an asterisk* next to the price. Always check website for most recently updated list. Best prices are in bold & underlined. Incoterms vary according to manufacturers.
Annual cost is calculated according to the daily doses given in the WHO ‘Scaling-up Antiretroviral Therapy in Resource Limited Settings: Guidelines for a Public Health Approach’ (June 2002) and/or the ‘Guidelines for the Use of Antiretroviral Agents in HIV Infected Adults and Adolescents’ from the Panel on Clinical Practices for the Treatment of HIV (2002).
For Roche, prices are given in Swiss Francs and were converted in US$ (1 US$ = 1.40 CHF on 15 April 2003)
PI (Abbreviation) |
indinavir (IDV) |
nelfinavir (NFV) |
ritonavir (r) |
saquinavir hard gel capsules (SQV hgc) |
Strength (mg) |
400 |
250 |
100 |
200 |
Trade name in Europe/US |
Crixivan® (Merck & Co. Inc.) |
Viracept® (Roche) |
Norvir® (Abbott) |
Invirase® (Roche) |
Daily dose |
4 (**) |
10 (***) |
2 (§) |
10 (#) |
Abbott (US) |
|
|
83* (0.114/unit) |
|
Merck & Co., Inc. (US) |
400 (0.274/unit) |
|
|
|
Roche (Switzerland) |
|
880* 0.241/unit (†) |
|
920* 0.252/unit (†) |
Aurobindo (India) |
393 (0.269/unit) |
1533 (0.420/unit) |
336 (0.460/unit) |
|
Cipla (India) |
406 (0.278/unit) |
2026 (0.555/unit) |
1084 (1.485/unit) |
|
Hetero (India) |
387 (0.265/unit) |
1500 (0.411/unit) |
219 (0.300/unit) |
1335 (0.366/unit) |
Ranbaxy (India) |
467 (0.320/unit) |
|
|
|
(**) The daily dose referred to is 800 mg IDV twice daily with ritonavir 100 mg twice daily as booster. The prescribing information given by the manufacturer is 800 mg three times daily
(***) The daily dose referred to is 1250 mg twice daily although the dosage of 9 tablets (3 tablets three times a day) can also be used.
(§) The daily dose referred to is 100 mg twice daily, for use as booster medication. This dose is not indicated in the manufacturer’s label.
(#) Invirase should be used in combination with low-dose ritonavir as Saquinavir/Ritonavir 1000 mg/100 mg twice daily
(†) Prices given in this table are for sub-Saharan Africa and Least Developed Countries as UN defined. In table 2d, also prices for Low Income and Lower Middle Income Countries, as classified by the World Bank, are given.