Adherence to Long-Term Therapies - Evidence for Action
(2003; 211 pages) View the PDF document
Table of Contents
View the documentPreface
View the documentAcknowledgements
View the documentScientific writers
View the documentIntroduction
View the documentTake-home messages
Open this folder and view contentsSection I - Setting the scene
Open this folder and view contentsSection II - Improving adherence rates: guidance for countries
Close this folderSection III - Disease-Specific Reviews
Open this folder and view contentsChapter VII - Asthma
Open this folder and view contentsChapter VIII - Cancer (Palliative care)
Open this folder and view contentsChapter IX - Depression
Open this folder and view contentsChapter X - Diabetes
Open this folder and view contentsChapter XI - Epilepsy
Open this folder and view contentsChapter XII - Human immunodeficiency virus and acquired immunodeficiency syndrome
Open this folder and view contentsChapter XIII - Hypertension
Open this folder and view contentsChapter XIV - Tobacco smoking cessation
Close this folderChapter XV - Tuberculosis
View the document1. Definition of adherence
View the document2. Factors that influence adherence to treatment
View the document3. Prediction of adherence
View the document4. Strategies to improve adherence to treatment
View the document5. Questions for future research
View the document6. References
Open this folder and view contentsAnnexes
Open this folder and view contentsWhere to find a copy of this book
 

5. Questions for future research

Useful research into human behaviour should take into account a wide range of approaches to enquiry, including qualitative and quantitative research methods. A review of the current literature on adherence to TB treatment has revealed a variety of research objectives, ranging from social and anthropological to clinical and programmatic studies. Further studies should be designed with the following aims:

• Define the theoretical models that underlie interventions to promote adherence to TB therapy.

• Describe the extent of various patterns of adherence (patients who take their medication sporadically, regularly take less than prescribed, and those who discontinue it completely).

• Explore the "active ingredients" of effective alliances between health providers and patients in a variety of sociocultural settings.

• Identify time-points in the case management at which different types of adherence strategy may have increased impact.

• Determine the efficacy and cost-effectiveness of specific interventions to improve adherence, as part of a complex health intervention necessary to achieve a high rate of treatment success.

• Priority should be given to studies in middle- and low-income countries to ensure the relevance of interventions to the settings in which most of the TB caseload occurs.

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