Nonadherence can take many different forms (19). The patient may simply fail to fill the prescription. If the prescription is filled, the patient may incorrectly time the medication or take the wrong dose because he or she misunderstood, or forgot, the health professional's instructions. Patients may also forget a dose completely or prematurely terminate the medication. Moreover, patients may self-adjust their regimen because of side-effects and toxicity or personal beliefs.