Adherence to Long-Term Therapies - Evidence for Action: Section III - Disease-Specific Reviews: Chapter VIII

Adherence to Long-Term Therapies - Evidence for Action
(2003; 211 pages)

Table of Contents

Preface
Acknowledgements
Scientific writers
Introduction
Take-home messages
Section I - Setting the scene
	Chapter I - Defining adherence
		1. What is adherence?
		2. The state-of-the-art measurement
		3. References
	Chapter II - The magnitude of the problem of poor adherence
		1. A worldwide problem of striking magnitude
		2. The impact of poor adherence grows as the burden of chronic diseases grows worldwide
		3. The poor are disproportionately affected
		4. References
	Chapter III - How does poor adherence affect policy-makers and health managers?
		1. Diabetes
		2. Hypertension
		3. Asthma
		4. References
Section II - Improving adherence rates: guidance for countries
	Chapter IV - Lessons learned
		1. Patients need to be supported, not blamed
		2. The consequences of poor adherence to long-term therapies are poor health outcomes and increased health care costs
		3. Improving adherence also enhances patient safety
		4. Adherence is an important modifier of health system effectiveness
		5. Improving adherence might be the best investment for tackling chronic conditions effectively
		6. Health systems must evolve to meet new challenges
		7. A multidisciplinary approach towards adherence is needed
		8. References
	Chapter V - Towards the solution
		1. Five interacting dimensions affect adherence
		2. Intervening in the five dimensions
		3. References
	Chapter VI - How can improved adherence be translated into health and economic benefits?
		1. Diabetes
		2. Hypertension
		3. Asthma
		4. References
Section III - Disease-Specific Reviews
	Chapter VII - Asthma
		1. Defining nonadherence to asthma therapy
		2. Rates of adherence to inhaled corticosteroids and other drugs for the prevention of asthma
		3. Forms of nonadherence
		4. Factors associated with adherence to asthma treatment
		5. Adherence in special populations
		6. Interventions to improve adherence to asthma therapy
		7. Discussion
		8. Conclusions
		9. References
	Chapter VIII - Cancer (Palliative care)
		1. Definitions and epidemiology of adherence
		2. Factors and interventions affecting adherence
		3. Conclusions
		4. References
	Chapter IX - Depression
		1. Research methods: measurement of adherence and sampling
		2. Rates of adherence
		3. Predictors of adherence
		4. Interventions to improve adherence
		5. Clinical implications and need for further research
		6. References
	Chapter X - Diabetes
		1. Introduction
		2. Treatment of diabetes
		3. Definition of adherence
		4. Prevalence of adherence to recommendations for diabetes treatment
		5. Correlates of adherence
		6. Interventions
		7. Methodological and conceptual issues in research on adherence to treatment for diabetes
		8. Conclusions
		9. References
	Chapter XI - Epilepsy
		1. Introduction
		2. Adherence to epilepsy therapy
		3. Epidemiology of adherence
		4. Factors affecting adherence and interventions used to improve it
		5. Conclusions
		6. References
	Chapter XII - Human immunodeficiency virus and acquired immunodeficiency syndrome
		1. Types of nonadherence
		2. Challenges in assessing adherence
		3. Predictors of adherence
		4. A framework for interventions to increase adherence
		5. Conclusions
		6. References
	Chapter XIII - Hypertension
		1. Prevalence of adherence to pharmacotherapy in patients with hypertension
		2. Impact of adherence on blood pressure control and cardiovascular outcome
		3. Adherence to non-pharmacological treatment
		4. Factors contributing to adherence
		5. Interventions for improving adherence
		6. Conclusions
		7. References
	Chapter XIV - Tobacco smoking cessation
		1. The burden of tobacco smoking
		2. Clinical guidelines and therapies available for tobacco smoking cessation
		3. Definitions
		4. Epidemiology of adherence
		5. Factors affecting adherence
		6. Interventions for improving adherence
		7. Cost, effectiveness and cost-effectiveness of adherence
		8. Conclusions
		9. References
	Chapter XV - Tuberculosis
		1. Definition of adherence
		2. Factors that influence adherence to treatment
		3. Prediction of adherence
		4. Strategies to improve adherence to treatment
		5. Questions for future research
		6. References
Annexes
	Annex I - Behavioural mechanisms explaining adherence
		1. Introduction
		2. The nature of poor adherence
		3. Determinants of adherence
		4. Models
		5. Interventions
		6. Conclusions
		7. References
	Annex II - Statements by stakeholders
		1. Family, community and patients' organizations
		2. Behavioural medicine
		3. General practitioners/family physicians
		4. Industry
		5. Nurses
		6. Pharmacists
		7. Psychologists
	Annex III - Table of reported factors by condition and dimension
	Annex IV - Table of reported interventions by condition and dimension
	Annex V - Global Adherence Interdisciplinary Network (GAIN)
		Scientists
		Professional, industry and patients' organizations
		Policy-makers
Where to find a copy of this book
	Officially designated depository libraries for WHO publications
	Reference libraries for WHO publications
	WHO official sales agents world wide
	Selected WHO publications of related interest
	A ready-to-use pamphlet for partners willing to promote this book

4. References

1. Cancer pain relief and palliative care. Report of a WHO Expert Committee. Geneva, World Health Organization, 1990 (WHO Technical Report Series, No. 804).

2. Addington-Hall J, McCarthy M. Dying from cancer: results of a national population- based investigation. Pall Medicine, 1995, 9: 295 - 305.

3. Jordhoy MS et al. Quality of life in palliative cancer care: results from a cluster randomized trial. Journal of Clinical Oncology, 2001, 19: 3884 - 3894.

4. National cancer control programmes: policies and managerial guidelines. Geneva, World Health Organization, 2002.

5. Cancer pain relief, 2nd ed. With a guide to opioid availability. Geneva, World Health Organization, 1996.

6. Miaskowski C et al. Lack of adherence with the analgesic regimen: a significant barrier to effective cancer pain management. Journal of Clinical Oncology, 2001, 19: 4275 - 4279.

7. Du Pen SL et al. Implementing guidelines for cancer pain management: results of a randomized controlled clinical trial. Journal of Clinical Oncology, 1999, 17: 361 - 370.

8. Ward SE et al. Patient-related barriers to management of cancer pain. Pain, 1993, 52: 319 - 324.

9. Zeppetella G. How do terminally ill patients at home take their medication? Palliative Medicine, 1999, 13: 469 - 475.

10. Ferrell BR, Juarez G, Borneman T. Use of routine and breakthrough analgesia in home care. Oncology Nursing Forum, 1999, 26: 1655 - 1661.

11. Ward S et al. Patient education in pain control. Supportive Care in Cancer, 2001, 9: 148 - 155.

12. Horne R, Weinman J. Patients' beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. Journal of Psychosomatic Research, 1999, 47: 555 - 567.

13. MacDonald N et al. A Canadian survey of issues in cancer pain management. Journal of Pain & Symptom Management, 1997, 14: 332 - 342.

14. Ferrell BR, Dean GE. Ethical issues in pain management at home. Journal of Palliative Care, 1994, 10: 67 - 72.

15. Mullen PD. Compliance becomes concordance. British Medical Journal, 1997, 314: 691 - 692.

16. Chelf JH et al. Cancer-related patient education: an overview of the last decade of evaluation and research. Oncology Nursing Forum, 2001, 28: 1139 - 1147.

17. de Wit R et al. Improving the quality of pain treatment by a tailored pain education programme for cancer patients in chronic pain. European Journal of Pain, 2001, 5: 241 - 256.

18. Rimer B et al. Enhancing cancer pain control regimens through patient education. Patient Education & Counseling, 1987, 10: 267 - 277.

19. Jones WL et al. Cancer patients' knowledge, beliefs, and behavior regarding pain control regimens: implications for education programs. Patient Education & Counseling, 1984, 5: 159 - 164.

20. Barriers and benefits of managing cancer pain at home. Geneva, World Health Organization, Cancer Pain Release 10, 1997.

21. Horne R, Weinman J. Patient's beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. Journal psychosomatic research. 1999, 47: 555 - 67.