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pharmaceuticals newsletter
WHO Pharmaceuticals Newsletter 1999, No. 03&04
(1999; 16 pages)
Table of Contents
Regulatory actions
Alatrofloxacin: revised labelling: incompatibility with certain diluents: Pfizer, USA
Beclometasone: recommended total daily dose in CFC-free inhalers: UK
Cholestin reinstated as a dietary product: federal judge overrules FDA decision: USA
Fluticasone: revised package insert: systemic eosinophilia: Glaxo Wellcome
Fosphenytoin sodium injection (Cerebyx): overdoses due to medication errors: label changes: Parke-Davis
Heparin-induced suppression of aldosterone secretion: product information revised: UK
Laxatives containing dantron and phenolphthalein: unacceptable ingredients in OTC drug products: USA
Nicotine chewing gum: available for general sale: UK
Nonprescription drugs: simplified labelling: USA
Rituximab (Mabthera): recommendations for safe use: UK
Troglitazone: application for re-introduction rejected: UK
Drug surveillance
ACE inhibitors: survey of renal monitoring: UK
Acenocoumarol: alopecia: Spain
Anti-thyroid drugs: agranulocytosis: UK
Cannabis: two clinical trials to start soon: UK
Clozapine: gastrointestinal obstruction: UK
Donepezil: review of adverse reactions: seizure and heart block: UK
Drugs and children: ADR reporting: new rules for paediatric trials of medicines: unlicensed drug use in neonates: UK
Ergotamine: interaction with HIV protease inhibitors: France, Switzerland
Fexofenadine: cardiac reaction: Netherlands
Inhaled corticosteroids: peri-oral dermatitis: Israel
Mirtazepine: intrahepatic cholestasis: Finland
Nicorandil: mouth ulcers: France
Orlistat: caution against nonprescription use: UK
Sildenafil: interaction with HIV protease inhibitors: UK
Sucralfate: bezoar formation: UK
Topiramate: transient hemiparesis: UK
New developments
Denileukin diftitox: novel treatment for rare form of cancer approved: USA
Desirudin: approved for use in orthopaedic surgery: UK
Etonorgestrel: single implant contraceptive: UK
Levonorgestrel: progestogen-only emergency contraception available: UK
Maggots: use in infected and necrotic wounds: UK
Temozolomide: a new treatment for brain cancer: UK
Vaccine for Lyme disease: approved: USA
New indications
New formulations
Newly approved products
Medical devices
Blood test for Lyme disease: approved: USA
Drug delivery systems: new devices under development: UK, USA
Wound dressings: pain-free removal: UK
Medication errors
Antimalarials: potential for prescribing errors: Netherlands
Celebrex: potential for errors: call to rename: USA
Equivalence code: potential to increase errors: USA
Syringe tip caps: potential hazard to infants: USA
Veterinary medicine
Antibiotics: four products banned from poultry and pig feeds: EU
Decoquinate: approved for the prevention of coccidiosis in calves: USA
Florfenicol: approved for the treatment of foot rot: USA
Narasin and nicarbazin with bacitracin methylene disalicylate: approved in broiler chicken feeds for prevention of coccidiosis: USA
WHO Pharmaceuticals Newsletter 1999, No. 03&04
Essential Drugs and Medicines Policy
WHO.INT
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