alprostadil

Viridal, Schwarz Pharma: Germany

injection substance 5 micrograms, 10 micrograms, 20 micrograms

prostaglandin-E1

Indications: Diagnosis and treatment of erectile dysfunction.

*cidofovir

Vistide, Pharmacia & Upjohn: France

solution for intravenous perfusion 375 mg/5 ml

antiviral agent

Indication: Cytomegalovirus retinitis in AIDS patients when other treatments are not considered appropriate.

*ebrotidine

Ulsan, Ferrer: Spain

scored tablet 400 mg

histamine H₁-receptor antagonist

Indication: Allergic rhinitis.

eprosartan

Teveten, SmithKline Beecham: Iceland

coated tablet 200, 300, 400 mg

antihypertensive (angiotensin II antagonist)

Indication: Essential hypertension.

icosapent

Omegaven, Fresenius: Germany

gelatin capsule 180 + 120 mg

fish lipid concentrate; antihyperlipidaemic

Indication: To provide intake of omega-3 fatty acids during parenteral nutrition.

ifosfamide

Holoxan, Asta Medica: Iceland

powder for injection 500 mg, 1000 mg, 2000 mg/ampoule

antineoplastic agent

Indications: Various malignancies.

irbesartan

Aprovel, Sanofi Winthrop: Spain

tablet 75 mg, 150 mg, 300 mg

antihypertensive (angiotensin II antagonist)

Indication: Essential hypertension.

loratadine + pseudoephedrine

Clarinex, Schering-Plough: Iceland

coated tablet 10 mg + 240 mg

histamine H₁-antagonist + vasoconstrictor

Indication: Allergic rhinitis.

mizolastine

Mizollen, Synthélabo: Spain; Mizollen, Lorex Synthélabo: UK

scored coated tablet 10 mg

histamine H₁-receptor antagonist

Indications: Symptomatic relief of seasonal allergic rhino-conjunctivitis, perennial allergic rhino- conjunctivitis and urticaria.

montelukast

Montelukast; Singulair, Merck, Sharp & Dohme: Germany, Spain, Switzerland

chewable tablet 5 mg; coated tablet 10 mg

antiallergy agent

Indication: Mild to moderate asthma for patients in whom other therapies are ineffective or inappropriate.

paclitaxel

Taxol, Bristol-Myers Squibb: Japan

concentrate for intravenous infusion 30 mg/vial

antineoplastic agent

Indication: Ovarian cancer.

perindopril erbumine

Coversyl, Servier: Japan

tablet 2 mg, 4 mg

angiotensin-converting enzyme (ACE) inhibitor

Indication: Hypertension.

*rabeprazole

Pariet, Eisai: Japan

enteric coated capsule 10 mg, 20 mg

antisecretory agent

Indications: Gastric ulcer, duodenal ulcer, stomal ulcer, reflux oesophagitis, Zollinger-Ellison syndrome.

Contraindications, precautions & warnings: As for other drugs of this class.

raltitrexed

Tomudex, Zeneca: Switzerland

powder for infusion 2 mg/vial

antineoplastic agent

Indications: [Not stated].

*ramipril + felodipine

Unimax, Astra: Norway

tablet 2.5 mg + 2.5 mg, 5 mg + 5 mg

angiotensin-converting enzyme (ACE) inhibitor + calcium channel blocker

Indication: Hypertension when monotherapy was ineffective.

salbutamol

Airomir, 3M Health Care: Iceland

aerosol inhaler 0.1 mg/dose

beta-adrenoreceptor agonist

Indication: Bronchial asthma.

saquinavir

Invirase, Nippon Roche: Japan

capsule 200 mg

antiretroviral agent

Indications: AIDS and symptomatic and asymptomatic HIV infections with CD4 cell counts of 500/mm3 or less, in combination with other antiretroviral agents.

sodium nitroprusside

Nitopro, Maruishi: Japan

solution for intravenous infusion 6 mg/2 ml ampoule; 30 mg/10 ml ampoule (0.3%)

antihypertensive

Indications: Intraoperative maintenance of hypotension; emergent intervention of abnormal intraoperative hypertension.

tazarotene

Zorac, Allergan: Switzerland

topical gel 0.5 mg/g, 1 mg/g

keratolytic agent

Indication: Psoriasis.

*tilactase

Lacdiges, Grogg: Switzerland

coated tablet 60 mg

enzyme

Indication: Enzyme substitution in lactose intolerance.

*tirofiban

Aggrastat, Merck Sharp Dohme & Chibret: Switzerland

infusion concentrate 0.25 mg/ml

thrombocyte aggregation antagonist

Indication: [Not stated].

topotecan

Hycamtin, SmithKline Beecham: Iceland

lyophilised powder for reconstitution 4 mg/vial

antineoplastic agent

Indication: Ovarian cancer.