Stability of Injectable Oxytocics in Tropical Climates: Results of Field Surveys and Simulation Studies on Ergometrine, Methylergometrine and Oxytocin - EDM Research Series No. 008
(1993; 50 pages) View the PDF document
Table of Contents
View the documentSummary
Open this folder and view contentsIntroduction
Open this folder and view contentsMaterials and methods
Open this folder and view contentsResults
Open this folder and view contentsDiscussion
View the documentConclusions and recommendations
View the documentReferences
Close this folderAnnexes
View the documentAnnex 1: Results of field studies on ergometrine injection
View the documentAnnex 2: Results of field studies on oxytocin injection
View the documentAnnex 3: Results of simulation studies
View the documentAnnex 4: Summary results of simulation studies
View the documentAnnex 5: Stability of (methyl) ergometrine injection (dark versus light)
View the documentAnnex 6: Comparison ergometrine vs. methylergometrine injection (2 brands each)
 

Annex 1: Results of field studies on ergometrine injection

Level of active ingredient in field samples, expressed as percentage of stated amount

Country

Facility

Manuf

Country of origin

Time since manuf (m)

Expired

Active ingredient (%)

           

90-110

80-89

60-79

<60

Malawi

MA-QEH

E5

India

36

     

66

 
 

MA-QEH

E6

Germany

22

     

74

 
 

MA-QEH

E1

Hungary

26

yes

       
 

MA-QEH

E7

Germany

10

     

61

 
 

MA-MAW

E7

Germany

10

       

42

 

MA-MAS

E7

Germany

10

       

34

 

MA-CHI

E7

Germany

10

       

56

 

MA-CHI

E1

Hungary

26

yes

       
 

MA-CHI

E8

Italy

33

   

86

   

Gambia

GA-CMS

E8

Italy

31

yes

       
 

GA-CMS

E9

Italy

36

yes

       
 

GA-CMS

E10

unknown

?

 

92

     
 

GA-CMS

E11

unknown

30

     

76

 

Sudan

SUD-IDA

E2

France

17

     

62

 
 

SUD-B

E2

France

17

       

52

 

SUD-B

E2

France

17

       

43

 

SUD-AH

E2

France

17

       

44

 

SUD-WH

E2

France

17

       

44

Zimbabwe

ZI-CMS

E12

Zimbab

3

 

98

     
 

ZI-CMS

E12

Zimbab

4

     

77

 
 

ZI-BB

E12

Zimbab

4

   

80

   
 

ZI-BB

E12

Zimbab

24

       

21

 

ZI-ZE

E1

Hungary

17

 

99

     
 

ZI-SM

E1

Hungary

17

 

95

     
 

ZI-HA

E1

Hungary

17

   

87

   
 

ZI-GU

E1

Hungary

17

   

86

   
 

ZI-NY

E1

Hungary

17

     

69

 
 

ZI-BIN

E1

Hungary

17

 

98

     
 

ZI-BB

E1

Hungary

17

 

98

     

Total

n=29

   

4

6

4

7

8

%

100%

   

14%

21%

14%

24%

28%

LEGEND

     

MA-QEH

Queen Elisabeth Hospital, Blantyre, Malawi

ZI-CMS

Central Medical Stores, Harare, Zimbabwe

MA-MAW

Machinga Distr Hospital, Malawi {in window)

ZI-BB

Beit Bridge Hospital Zimbabwe

MA-MAS

Machinga Distr Hospital, Malawi (in store)

ZI-BIN

Binga Hospital, Zimbabwe

MA-CHI

Chikwawa District Hospital, Malawi

ZI-ZE

Zenka Hospital, Zimbabwe

GA-CMS

Central Medical Stores, Banjul, Gambia

ZI-SM

St Michael Hospital, Zimbabwe

SUD-IDA

Reference sample, IDA, Amsterdam

ZI-HA

Hanna Hospital, Zimbabwe

SUD-B

Berber hospital. Nile Province, Sudan

ZI-GU

Gumira Hospital, Zimbabwe

SUD-AH

Abu Hamed Hospital, Nile Province, Sudan

ZI-NY

Nyamatawa Hospital, Zimbabwe

SUD-WH

Wad Hamid Hospital, Nile Province, Sudan

   
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Last updated: May 3, 2013