Product name:

Alatrofloxacin mesilate

CAS number:

157605-25-9

Synonyms:

7-{(1R,5S,6s)-6-[(S)-2-Aminopropionamido)propionamido]-3-azabicyclo[3.1.0]hex- 3-yl}-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3- carboxylic acid monomethanesulphonate

Country

Effective Date

Description of action taken
Grounds for decision

Armenia

July 2000

The Drug and Medical Technology Agency have rejected registration of alatrofloxacin because recent studies have shown serious and unpredictable liver injuries after administration of the drug. (Reference: Communication to WHO, 9 August 2000)

Singapore

The National Pharmaceutical Administration in the Ministry of Health has not approved alatrofloxacin since it is associated with hepatic adverse reactions. (Reference: Communication to WHO, 2 August 2000.)