WHO Drug Information Vol. 15, No. 3 & 4, 2001
(2001; 76 pages) View the PDF document
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View the documentWHO Drug Information
Open this folder and view contentsPersonal Perspectives
Open this folder and view contentsReports on Individual Drugs
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Close this folderRegulatory and Safety Matters*
View the documentInfliximab and congestive heart failure
View the documentInfliximab: warning of opportunistic infections
View the documentBrimonidine ophthalmic drops: accidental ingestion
View the documentP-Glycoprotein and drug interaction
View the documentNonacog alfa: intensive surveillance
View the documentTenofovir disoproxil fumarate approved for HIV infection
View the documentCiprofloxacin hydrochloride for inhalation anthrax
View the documentDTPa and limb swelling
View the documentNitrofurantoin and peripheral neuropathy
View the documentContinued suspension for tolcapone
View the documentMMR vaccine and idiopathic thrombocytopenic purpura
View the documentNew communications and networking unit at EMEA
Open this folder and view contentsATC/DDD Classification
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View the documentRecommended International Nonproprietary Names (rec. Inn): List 46
View the documentSelected WHO Publications of Related Interest
 

Brimonidine ophthalmic drops: accidental ingestion

Canada - Accidental oral ingestion of brimonidine ophthalmic drops (about 2 mL) in a 28-month-old child caused decreased consciousness and apnea resulting in intubation, ventilation and surveillance in an intensive care unit for 40 hours. Recommendations for child-resistant packaging were made to the manufacturer. As an immediate option to reduce the risk of accidental exposure, consider dispensing these ophthalmic drops in childproof vials.

Reference: Canadian Adverse Drug Reaction Newsletter, Volume 11(4) on http://www.hc-sc.gc.ca/hpb-dgps/therapeut/zfiles/

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