Safe and Effective: Use of Antiretroviral Treatments in Adults with Particular Reference to Resource Limited Settings: SECTION TWO. SOME EXPERIENCES WITH ART IN RESOURCE LIMITED SETTINGS: 2.3. QUALITY OF CARE AND OUTCOMES

Safe and Effective: Use of Antiretroviral Treatments in Adults with Particular Reference to Resource Limited Settings
(2001; 36 pages) [French]

Table of Contents

	ACKNOWLEDGEMENTS
	INTRODUCTION
	SECTION ONE. PRINCIPLES OF ANTIRETROVIRAL THERAPY (ART)*
		1.1. BACKGROUND
		1.2. CHARACTERISTICS OF AVAILABLE ANTIRETROVIRAL DRUGS
		1.3. INITIATION OF THERAPY
		1.4. MONITORING
		1.5. TREATMENT FAILURE
		1.6. HIV RESISTANCE TO ANTIRETROVIRAL DRUGS
		1.7. FUTURE APPROACHES TO THERAPY
	SECTION TWO. SOME EXPERIENCES WITH ART IN RESOURCE LIMITED SETTINGS
		2.1. ART COVERAGE
		2.2. CONTEXT: PUBLIC OR PRIVATE SECTOR, DONOR SUPPORTED AND RESEARCH PROJECTS
		2.3. QUALITY OF CARE AND OUTCOMES
		2.4. LABORATORY MONITORING SERVICES
		2.5. SURVEILLANCE FOR DRUG RESISTANCE
		2.6. SUPPLY AND DISTRIBUTION OF THE DRUGS
		2.7. INITIATION OF TREATMENT
		2.8. CHOICE OF THERAPEUTIC REGIMEN
	SECTION THREE. GUIDE TO ART IN RESOURCE LIMITED SETTINGS
		3.1. WHAT SHOULD BE IN PLACE BEFORE INITIATING ART PROGRAMMES*
		3.2. COUNSELLING FOR ART
		3.3. CLINICAL EVALUATION BEFORE INITIATION OF ART
		3.4. INITIATION OF THERAPY
		3.5. MONITORING ANTIRETROVIRAL THERAPY*
		3.6. CONSIDERATIONS OF DRUG INTERACTIONS
		3.7. FURTHER RESEARCH NEEDS
		3.8. INFORMATION AND TRAINING NEEDS
	ANNEX I. LIST OF PARTICIPANTS
	ANNEX II. DRUG CHARTS

2.3. QUALITY OF CARE AND OUTCOMES

Available data suggest that the clinical outcomes of treatment, in the context of centres of excellence, externally funded projects or clinical trials, are very similar to those in industrialised countries. From about 1997, HIV care centres in 2 large Brazilian cities have recorded a significant decrease in the number of AIDS deaths, a reduction in the prevalence of major HIV related opportunistic infections and an overall decrease in the number of hospitalisations for HIV related illnesses. In the context of unregulated practice, the quality of care and the outcomes of treatment may be different but because such situations are difficult to evaluate, there is no information available.