Guidelines for the Management of Sexually Transmitted Infections. February 2004
(2004; 88 pages)
Table of Contents
View the documentPREFACE
Open this folder and view contents1. INTRODUCTION
Open this folder and view contents2. TREATMENT OF STI-ASSOCIATED SYNDROMES
Close this folder3. TREATMENT OF SPECIFIC INFECTIONS
Open this folder and view contents3.1. Gonococcal infections
Open this folder and view contents3.2. Chlamydia trachomatis infections (other than lymphogranuloma venereum)
View the document3.3. Lymphogranuloma venereum
Open this folder and view contents3.4. Syphilis
View the document3.5. Chancroid
View the document3.6. Granuloma inguinale (Donovanosis)
Open this folder and view contents3.7. Genital herpes infections
Open this folder and view contents3.8. Venereal warts
View the document3.9. Trichomonas vaginalis infections
Close this folder3.10. Bacterial vaginosis
View the documentBacterial vaginosis in pregnancy
Open this folder and view contents3.11. Candidiasis
View the document3.12. Scabies
View the document3.13. Phthiriasis (pediculosis pubis)
Open this folder and view contents4. KEY CONSIDERATIONS UNDERLYING TREATMENTS
Open this folder and view contents5. PRACTICAL CONSIDERATIONS IN STI CASE MANAGEMENT
Open this folder and view contents6. CHILDREN6, ADOLESCENTS AND SEXUALLY TRANSMITTED INFECTIONS
View the documentANNEX. LIST OF PARTICIPANTS
 

Bacterial vaginosis in pregnancy

There is evidence that bacterial vaginosis is associated with an increased incidence of adverse pregnancy outcomes (e.g., premature rupture of membranes, pre-term delivery and low birth weight). Symptomatic pregnant women should be treated, and those with a history of previous pre-term delivery should be screened to detect asymptomatic infections. Pregnant women with recurrence of symptoms should be re-treated. Screening of asymptomatic pregnant women without a history of prior pre-term delivery is not recommended.

Metronidazole is not recommended for use in the first trimester of pregnancy, but it may be used during the second and third trimesters. Lower doses of metronidazole are recommended throughout pregnancy, to reduce the risks of any adverse effects.

Recommended regimen

• metronidazole, 200 or 250mg orally three times daily for 7 days.

Alternative regimens

• metronidazole, 2g orally, as a single dose

OR

• clindamycin, 300 mg orally twice daily for 7 days

OR

• metronidazole gel, 0.75%, 5g twice daily intravaginally for 7 days.

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