WHO Model Prescribing Information: Drugs Used in Anaesthesia
(1989; 60 pages) [French] View the PDF document
Table of Contents
View the documentPreface
View the documentIntroduction
Open this folder and view contentsPremedication
Open this folder and view contentsGeneral anaesthetics and oxygen
Open this folder and view contentsLocal anaesthetics
Open this folder and view contentsNon-opioid analgesics
Open this folder and view contentsOpioid analgesics and antagonists
Open this folder and view contentsMuscle relaxants and cholinesterase inhibitors
Open this folder and view contentsBlood substitutes
Open this folder and view contentsSolutions for correcting water and electrolyte imbalance
Close this folderAntacid for use in obstetric practice
View the documentSodium citrate
View the documentAnaesthesia at the District Hospital
View the documentSelected WHO publications of related interest
View the documentBack cover

Sodium citrate

Group: antacid
Oral solution: 88.2 mg/ml (8.82%, 0.3 mmol/ml)

General information

Sodium citrate is an alkalinizing agent which depends for its activity upon conversion to bicarbonate.

Clinical information


To protect against the risk of aspiration of acidic gastric contents in women undergoing operative obstetric procedures.

Dosage and administration

A dose of 10-20 ml of the solution should be given immediately before the procedure.


• Severe renal impairment.


Sodium citrate solution should be used with particular care in patients with hypertension or toxaemia in pregnancy.

Adverse effects

It is generally well tolerated. Metabolic alkalosis may occur in patients with renal dysfunction.


The solution should be stored in tightly closed containers.

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