WHO Model Prescribing Information: Drugs Used in Anaesthesia
(1989; 60 pages) [French] View the PDF document
Table of Contents
View the documentPreface
View the documentIntroduction
Open this folder and view contentsPremedication
Open this folder and view contentsGeneral anaesthetics and oxygen
Open this folder and view contentsLocal anaesthetics
Open this folder and view contentsNon-opioid analgesics
Open this folder and view contentsOpioid analgesics and antagonists
Open this folder and view contentsMuscle relaxants and cholinesterase inhibitors
Open this folder and view contentsBlood substitutes
Close this folderSolutions for correcting water and electrolyte imbalance
View the documentCompound solution of sodium lactate
View the documentGlucose
View the documentGlucose with sodium chloride
View the documentSodium chloride
View the documentPotassium chloride
Open this folder and view contentsAntacid for use in obstetric practice
View the documentAnaesthesia at the District Hospital
View the documentSelected WHO publications of related interest
View the documentBack cover


Group: intravenous infusion fluid
Injectable isotonic solution: 50 mg/ml (5%)

Clinical information


• Postoperative fluid replacement in patients with no sodium deficit, until adequate fluid can be taken by mouth.

• Intravenous rehydration of patients suffering from water depletion for whom oral rehydration salts are not suitable.

Dosage and administration

Individual requirements should always be determined on the basis of clinical and, whenever possible, electrolyte monitoring.


Patients must be monitored for signs of intravascular overload. In this event infusion must be slowed or suspended and, if necessary, a rapidly acting diuretic administered (for example furosemide 40 mg i.v.).

Patients with overt or known diabetes additionally require insulin and close biochemical monitoring.

Prolonged parenteral infusion of glucose solutions may inhibit secretion of insulin. To minimize the risk of hyperglycaemia it may be necessary to add insulin to the infusion.

Adverse effects

Infusion of large volumes of glucose solution may cause hyponatraemia.

Unduly rapid replacement may lead to pulmonary oedema.


Glucose solution should be kept in sealed containers.

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