Solution, 0.5%

General information

Silver nitrate is a powerful anti-infective agent that is used as an astringent and as a caustic and an antiseptic agent. It is poorly absorbed, even when applied to the mucous membranes.

Clinical information

Uses

An antiseptic agent used in wet dressings to assist healing of suppurating superficial wounds, tropical ulcers and lesions caused by pemphigus.

Dosage and administration

All doses are suitable for adults and children.

Suppurating superficial wounds and tropical ulcers:

A 1:100 dilution of the stock solution is used in wet dressings. The dressings should be changed twice or 3 times daily. For tropical ulcers, a 2- to 4-week course of treatment with procaine benzylpenicillin is also required (see Benzylpenicillins - Tropical Ulcers).

Pemphigus:

Compresses soaked in a 1:100 dilution of the stock solution are applied every 4 hours.

Precautions

Dressings should not be applied under plastic or rubber occlusion.

Adverse effects

Skin irritation is common. Permanent staining of clothing and bedding also occurs.

Storage

Solutions should be stored in well-closed containers, protected from light.