(1997; 132 pages) [French] [Spanish]
Methylrosanilinium chloride (gentian violet)
Aqueous solution, 0.5%
Methylrosanilinium chloride is a triphenylmethane dye. It inhibits the growth of many fungi including yeasts and is also active against some Gram-positive bacilli.
Methylrosanilinium chloride is widely available and relatively inexpensive.
• superficial dermatophyte infections
• cutaneous, mucocutaneous and vaginal candidosis
• intertriginous seborrhoeic dermatitis
• superficial bacterial pyodermas.
Dosage and administration
Adults and children: topical application twice or three times daily produces significant clearing of responsive lesions within a few days.
Known hypersensitivity to the dye.
Treatment should be withdrawn immediately should a rash or any other signs of hypersensitivity occur. Patients should be warned that temporary staining of the skin and permanent staining of clothing may occur.
Use in pregnancy
Safe use in pregnancy has not been established. Treatment should be deferred until after delivery.
Methylrosanilinium chloride is usually well tolerated. Occasionally severe irritation occurs, which may necessitate discontinuation of treatment.
The solution should be stored in tightly closed containers, protected from light.