(1997; 248 pages) [French]
4.3 Quality surveillance during distribution
In the process of quality surveillance during distribution particular attention should be paid to personnel qualifications, storage facilities and transport conditions.
Every pharmaceutical product has a shelf-life during which its quality may be expected to remain within acceptable limits, but which may be seriously shortened by improper storage conditions. There is therefore a need to ensure - especially in adverse climatic conditions - that during all phases of distribution adequate conditions of storage are maintained.
For drugs that are known to have a short shelf-life, the expiry date should be stated clearly (no code being used) on all drug labels. The inclusion of expiry dates on the labelling provides a uniform system of indicating shelf-life under specified conditions of storage. In addition, the indication of the date of manufacture would further facilitate the quality surveillance of pharmaceutical products during distribution.