Guidelines on the Use of International Nonproprietary Names (INNs) for Pharmaceutical Substances
(1997; 41 pages) View the PDF document
Table of Contents
Open this folder and view contents1. General introduction
Close this folder2. Elements in the INN system
View the document2.1 Proposed INNs
View the document2.2 Recommended INNs
View the document2.3 Names for radicals and groups
View the document2.4 Modified INNs (INNMs)
View the document2.5 Cumulative list of INNs
Open this folder and view contents3. Principles for selection of INNs
View the document4. Protection of INNs
Open this folder and view contents5. How to apply for an INN
View the document6. References for supporting material
View the documentAnnex 1: Background information on the INN programme
View the documentAnnex 2: General principles for guidance in devising international nonproprietary names for pharmaceutical substances
View the documentAnnex 3: List of common stems used in the selection of INNs
View the documentAnnex 4: Specific groups of biological compounds
View the documentAnnex 5: WHA46.19 - Nonproprietary names for pharmaceutical substances
View the documentAnnex 6: Procedure for the selection of international nonproprietary names for pharmaceutical substances
View the documentAnnex 7: Applications for INNs through national authorities (addresses)
View the documentAnnex 8: INN request form

2.5 Cumulative list of INNs

All names selected as proposed and recommended INNs are published in a Cumulative list, which is updated periodically. The generic names are presented in alphabetical order by Latin name. Each entry includes:

• equivalent nonproprietary names: in Latin, English, French, Russian and Spanish;

• reference to the INN list in which the name was originally proposed or recommended, or last amended;

• reference to names of substances that have been abandoned or never been marketed;

• reference to national nonproprietary names;

• reference to pharmacopoeial monographs or similar official references;

• reference to names issued by the International Organization for Standardization (ISO);

• reference to the Convention of Psychotropic Substances, if applicable;

• reference to the List of Narcotic Drugs under International Control, if applicable;

• the molecular formula;

• its Chemical Abstracts Service (CAS) number.

The layout for information contained in the Cumulative list of INNs is as follows:

Note: Cross-references are provided for entries corresponding to (a) English, French and Spanish INN that appear in different alphabetical positions from the Latin INN and (b) national names that differ from the INN. Entries for (a) are printed in lower-case letters (as in the example of aceburic acid, below) while entries for (b) are printed in capitals (as in the examples of ACEBUTOLOL HYDROCHLORIDE and ACEBUTOLOLO).


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