(1997; 41 pages)
2.3 Names for radicals and groups
During the 1975 meeting on Nonproprietary Names for Pharmaceutical Substances the experts discussed the issue of INNs for salts and esters and noted that requests had frequently been received for INNs for salts, esters, or combination products of substances for which INNs already existed. At that time, the experts decided that INNs for the simple salt and esters should be devised from the INN in conformity with normal chemical practice.
Some of the radicals and groups involved are, however, of such complex composition that it makes it inconvenient to use the chemical nomenclature. It was thus decided that in such cases, shorter nonproprietary names are selected for these inactive moieties and published in proposed lists under the title “Names for Radicals and Groups”. Separate names for salts and esters derived from this procedure are not published. If a “radical and group name” is used in conjunction with an INN, they are referred to as International Nonproprietary Name (Modified) or INNM.
A comprehensive list of radicals and groups may be obtained from the Distribution and Sales unit or the INN Secretariat (INNs: Names for radicals and groups, combined summary list, WHO/PHARM S/NOM 1506, updated regularly).