(1999; 168 pages) [Spanish]
3.3 Use of International Chemical Reference Substances and Infrared Reference Spectra
The results of a questionnaire on the use of International Chemical Reference Substances and Infrared Reference Spectra were reported to the Committee. The majority of the answers came from national quality control laboratories (40.4%), pharmaceutical manufacturers (22.6%) and teaching and research institutions (19.8%). It was noted that the substances are mainly used as primary standards to calibrate working standards, but also to some extent directly as working standards. This probably reflects a single or infrequent use where it is not sensible to prepare a secondary standard. The Committee recommended that the WHO Collaborating Centre for Chemical Reference Substances should conduct a follow-up exercise and report on its results at the next meeting of the Expert Committee.