Malaria in pregnancy

Malaria in pregnancy increases the risk of maternal anaemia, stillbirth, spontaneous abortion, low birth weight and neonatal death. WHO recommends a package of interventions for the prevention and control of malaria during pregnancy:

  1. Use of insecticide treated nets (ITNs) to prevent infection
  2. Intermittent Preventive Treatment (IPT) to prevent asymptomatic infections among pregnant women living in areas of moderate or high transmission of P. falciparum
  3. Effective case management for malaria illness and anaemia.

 

     

  • Technical reports and publications:
  • Technical Expert Group meeting on intermittent preventive treatment in pregnancy (IPTp)
    WHO HEADQUARTERS, GENEVA, 11–13 JULY 2007

    The Global Malaria Programme/WHO held a technical consultation in Geneva on 11.13 July 2007 to appraise available evidence on IPTp against the background of the various limitations and changing environment described above, with the primary objective of:
    1. Developing a framework, plan, and methodology to monitor and evaluate the efficacy and effectiveness of on going SP-IPTp:
    2. Reviewing the evidence on efficacy and safety of SP-IPTp, with a view to updating WHO guidelines on IPTp.
    3. Identifying gaps in knowledge and defining a research agenda for IPTp for guiding future policy direction. The panel comprised of 15 independent Experts. The Consultation was attended by observers from UNICEF, the Bill and Melinda Gates foundation, and the IPTi Consortium (Appendix 1, List of participants).



    Assessment of the Safety of Artemisinin Compounds in Pregnancy
    WHO/CDS/MAL/20903.1094
    WHO/GMP/TDR/Artemisinin/07.1

    In 2006 WHO/GMP and TDR convened joint informal consultations to review existing data and policies on the use of artemisinin compounds in pregnancy. At the first consultation experts in reproductive and developmental toxicity discussed new published and unpublished data on the toxicity of artemisinins in rodents and primates. In addition, studies using whole embryo culture as well as isolated cells were reviewed. A second consultation reviewed the recent safety and efficacy data on the use of artemisinin compounds in early pregnancy and outlined new approaches needed to obtain more safety information.


    A Strategic Framework for Malaria Prevention and Control during Pregnancy in the African Region
    AFR/MAL/04/01
    Guidance for policy-makers and national programmes on the prevention and control of malaria in pregnant women.


    Recommendations on the use of Sulfadoxine-Pyrimethamine (SP) for Intermittent Preventive Treatment during Pregnancy (IPT) in areas of moderate to high resistance to SP in the African Region
    October 2005


    Malaria in Pregnancy: Guidelines for Measuring Key Monitoring and Evaluation Indicators
    WHO 2007
    ISBN:978 92 4 159 563 6
    Provides guidance for countries on the monitoring and evaluation of malaria in pregnancy programmes.
    [Version française]


    Prevention of malaria in pregnancy
    Recommendations
    WHO Expert Committee recommendation
    WHO Technical Report Series — 892
    WHO Expert Commitee on Malaria recommends Intermittent Preventive Treatment of malaria in pregnancy.


  • Journal articles:
  • P Marchesini, J Crawley Reducing the burden of malaria in pregnancy PDF version
    Mera, January 2004
    Short review that describes the tools that are currently available for the prevention and control of malaria in pregnancy.

     

    M Parise, L Lewi, J Ayisi, B Nahlen, L Slutsker, R Muga. A Rapid Assessment Approach for Public Health Decision-making Related to the Prevention of Malaria during Pregnancy PDF version
    Bulletin of the World Health Organization 2003, 81 (5)
    The article describes a rapid field assessment methodology for addressing the burden of malaria during pregnancy.

  • Useful links:
  • RELATED LINKS


    /* */