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Results 1-10 of 22.
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Skin sensitization in chemical risk assessment
International Programme on Chemical Safety ( 2008 )
Principles for the assessment of risks to human health from exposure to chemicals
World Health Organization; International Programme on Chemical Safety ( 1999 )
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Chemical safety : metabolism and toxicity, collected lectures
World Health Organization. Promotion of Chemical Safety Unit; International Programme on Chemical Safety ( 1993 )
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General scientific principles of chemical safety / scientific editor: L. Fishbein
Fishbein, Lawrence; World Health Organization. Chemical Safety Team; International Programme on Chemical Safety; Inter-Organization Programme for the Sound Management of Chemicals ( 2000 )
Principles for evaluating health risks from chemicals during infancy and early childhood : the need for a special approach / published under the joint sposorship of the United Nations Environment Programme, the International Labour Organisation, the World Health Organization, and on behalf of the Commission of the European Communities
International Programme on Chemical Safety; Commission of the European Communities; United Nations Environment Programme; International Labour Organization; World Health Organization ( 1986 )
Abstract

Elaborates basic principles for the evaluation of chemical toxicology that are specific to the physiological characteristics of infants and young children. Principles of evaluation, which were worked out by 46 leading experts, are based on a thorough review of data on postnatal physiology, metabolism, and the special factors governing exposure in this age group, including behavioural and cultural conditions. Following background information on relevant features of postnatal morphology, biochemistry, and physiology, chapters assess the kinetics of absorption, biotransformation, and elimination and point out ways in which certain conditions of postnatal development will influence the effects of chemicals on different organs and systems. The book concludes with a discussion of factors that can assist in the identification of children at risk

Principles and methods for the assessment of neurotoxicity associated with exposure to chemicals / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
World Health Organization; United Nations Environment Programme; International Labour Organization; International Programme on Chemical Safety ( 1986 )
Abstract

A detailed evaluation of the principles and methods currently used to explore the association between exposure to chemicals and the development of adverse neurobehavioural changes. Emphasis is placed on the use of animals as systems to model and predict adverse reactions in the human nervous system. The book has five sections. The first deals with general factors to be considered in the design of neurotoxicity studies and in the statistical analysis of their results. Experience acquired in the recent outbreaks of poisoning from methyl mercury and carbon disulfide are used to demonstrate both the importance of evaluating the neurotoxicity of chemicals and the power of animal studies to predict human responses. The remaining sections provide extensive information on methods developed in each of the four major research disciplines that contribute to the neurotoxic assessment of environmental chemicals

Principles of toxicokinetic studies / published under the joint sponsorship of the United Nations Environment Programme, International Labour Organisation, and the World Health Organization
International Programme on Chemical Safety; IPCS Task Force on Toxicokinetics ( 1986 )
Abstract

A guide to the use of toxicokinetic methods in the evaluation of human health risks associated with environmental exposure to xenobiotics. Sections cover the quantitative evaluation of data on absorption, disposition, and clearance and offer extensive advice on sampling procedures, methods, and models for studies of xenobiotic metabolism

Methods for estimating risk of chemical injury : human and non-human biota and ecosystems / edited by Velimir B. Vouk ... [et al.] ; prepared by Scientific Group on Methodologies for the Safety Evaluation of Chemicals
Vouk, Velimir B; Butler, Gordon C; Hoel, David G; Peakall, David B; International Council of Scientific Unions. Scientific Committee on Problems of the Environment; Scientific Group on Methodologies for the Safety Evaluation of Chemicals; International Programme on Chemical Safety ( 1985 )
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Principles of characterizing and applying human exposure models
International Programme on Chemical Safety ( 2005 )
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Chemical-specific adjustment factors for interspecies differences and human variability : guidance document for use of data in dose/concentration-response assessment
International Programme on Chemical Safety; IPCS Workshop on Incorporating Uncertainty and Variability into Risk Assessment (2000 : Berlin, Germany) ( 2005 )