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Results 1-10 of 47.
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1,3-Butadiene : human health aspects
Hughes, K; International Programme on Chemical Safety ( 2001 )
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2-Furaldehyde
Cary, R; Dobson, Stuart; Gregg, N; World Health Organization; International Programme on Chemical Safety ( 2000 )
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Dinitro-orto-cresol
Pelfrène, A. F; World Health Organization; International Programme on Chemical Safety ( 2000 )
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Chlorine dioxide (gas)
Dobson, Stuart; Cary, Richard; International Programme on Chemical Safety ( 2002 )
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Chrysotile asbestos
World Health Organization; International Programme on Chemical Safety ( 1998 )
Copper
World Health Organization; International Programme on Chemical Safety ( 1998 )
Principles and methods for assessing allergic hypersensitization associated with exposure to chemicals
World Health Organization; International Programme on Chemical Safety ( 1999 )
Health effects of interactions between tobacco use and exposure to other agents
Rothwell, K; World Health Organization; International Programme on Chemical Safety ( 1999 )
Brominated diphenyl ethers / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
World Health Organization; International Programme on Chemical Safety ( 1994 )
Abstract

Evaluates the risks to human health and the environment posed by exposure to ten brominated diphenyl ethers. Of these, three (decabromodiphenyl ether, octabromodiphenyl ether, and pentabromodiphenyl ether) are widely manufactured and used as additive flame retardants. The remaining seven compounds occur as contaminants or impurities in commercial brominated flame retardants. Because of their success in reducing fire hazards for the general public, brominated biphenyl ethers are used in increasing quantities in a wide range of products. Concern about potential risks to human health and the environment has centered on the persistence of these chemicals in the environment, thir tendency to bioaccumulate, their detection in several food items and in human adipose tissue and milk, their tendency to leach or escape from finished products during normal operation, and the release of polybrominated dibenzofurans and polybrominated dibenzodioxins as breakdown products under certain conditions. For decabromodiphenyl ether, which is the most important of these products, the report cites evidence of persistence in the environment, accumulation in sediment and soil, occupational exposure during manufacturing and formulation, and an insignificant exposure of the general population. Similar risks to the environment were found for octabromodiphenyl ether. For pentabromodiphenyl ether, evidence of environmental hazards and potential human exposure via the food chain supports the conclusion that this product should not be used. In its conclusions, the report stresses the need to minimize environmental contamination with these persistent compounds and their breakdown products. Introduction of such chemicals into widely used products may create a considerable long-term diffuse source of emissions into the environment

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Dichloropropene, dichloropropane and mixtures / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
World Health Organization; International Programme on Chemical Safety ( 1993 )
Abstract

Evaluates the risks to human health and the environment posed by 1,3-dichloropropene, 1,2-dichloropropane and mixtures of these chemicals. Since the two compounds and mixtures have been widely used in agriculture as pre-plant fumigants applied by soil injection, the report gives particular attention to studies investigating behaviour in soil, risks of leaching and groundwater contamination, uptake by food crops, residues detected in drinking-water and food, and risks to agricultural workers and the general population. Over 300 studies, including proprietary toxicological data from the manufacturers, were critically assessed. The report concludes that, when used at the recommended rate, 1,3-dichloropropene is unlikely to attain levels of environmental significance. Risks to the general population were judged negligible. Concerning occupational hazards, the report cites evidence, largely from case reports of poisoning, underscoring the need to follow appropriate safety precautions. The report concludes that 1,2-dichloropropane poses a negligible risk to the general population. When used at the recommended rate, the compound is unlikely to attain levels of environmental significance. For workers, the compound is judged unlikely to pose a hazard, provided good work practices, hygienic measures, and safety precautions are followed. Data on mixtures of dichloropropenes and dichloropropane are evaluated in the final monograph. This technical mixture previously enjoyed wide use as a soil nematocide before planting. Citing evidence of a significant potential for 1,2-dichloropropane derived from this mixture to leach from soil and contaminate well water and groundwater, the report recommends that mixtures of dichloropropenes and dichloropropane should not be used as a soil fumigant