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Trichloroethylene
International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization; World Health Organization ( 1985 )
Abstract

Trichloroethylene is a liquid with extensive applications in metal degreasing, textile cleaning, solvent extraction processes, and as a carrier solvent. Exposure in the workplace, which may occur via inhalation of the vapour or skin contamination with the liquid, is known to carry risks of central nervous system disturbances and liver and kidney damage. This report provides a thorough assessment of the risks to human health and the environment posed by the industrial use of trichloroethylene. Coverage ranges from a survey of analytical methods for assessing levels in human tissues and fluids, through a list of signs and symptoms of over-exposure in man and the treatment of poisoning, to a statement of precautions to follow in handling, storage, and disposal

Evaluation of short-term tests for carcinogens : report of the International Programme on Chemical Safety's Collaborative Study on In Vitro Assays / edited by John Ashby ... [et al.]
Ashby, John; International Programme on Chemical Safety; World Health Organization; International Labour Organization; United Nations Environment Programme ( 1985 )
Butanols - four isomers : 1-butanol, 2-butanol, tert-butanol, isobutanol / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization, and the World Health Organization
International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization; World Health Organization ( 1987 )
Abstract

Presents individual monographs on the risks to health and the environment associated with 1-butanol, 2-butanol, tert-butanol, and isobutanol. These butanol isomers, which occur naturally as products of fermentation, are also synthesized from petrochemicals and widely used as solvents and intermediates in chemical industries. Human exposure to high concentrations is primarily occupational, while exposure to low concentrations is mainly through foods in which the isomers occur either naturally or as flavouring agents. Although the butanol isomers can be classified as slightly or practically nontoxic, all isomers, in large amounts, have the ability to induce signs of alcoholic intoxication in both animals and man. The most extensive section of each monograph covers data on biological effects observed in experimental animals, in in vitro test systems, and in cases of accidental occupational exposure in man. Particular attention is given to studies useful in assessing effects on the skin, eyes, and respiratory tract of workers exposed to these chemicals

Chlorothalonil : health and safety guide
World Health Organization; International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization ( 1995 )
Fluorine and fluorides / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization; World Health Organization; IPCS Task Group on Environmental Health Criteria for Fluorine and Fluorides ( 1984 )
Abstract

An expert assessment of both the beneficial and toxic effects to human health posed by the use of fluorine and fluorides. Conclusions and recommendations are based on a critical analysis of well over 400 clinical and laboratory investigations. The introductory sections consider methods for the measurement of fluorides in inorganic and organic materials, sources and magnitude of exposure, and effects on health as determined through a large number of laboratory investigations. The most extensive section is devoted to a critical review of data on beneficial and toxic effects in humans. Beneficial effects of fluoride in drinking water, salt, milk, tablets, and topical applications are considered in terms of the preventive effects on dental caries and their use in the treatment of osteoporosis. Toxic effects reviewed include various forms of fluorosis, effects on renal function, hypersensitivity and dermatological reactions, and carcinogenic and teratogenic risks. On the basis of this review, the report confirms the beneficial effects of fluoride in the prevention of caries, while noting that long-term exposure to high quantities may damage enamel and bone; very high doses cause acute toxic effects and may be lethal

Chlordane / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization; World Health Organization; WHO Task Group Meeting on Environmental Health Criteria for Organochlorine Pesticides other than DDT (Chlordane) Heptachlor Mirex Chlordecone Kelevan Camphechlor ( 1984 )
Epichlorohydrin / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization; World Health Organization; WHO Task Group on Environmental Health Criteria for Epichlorohydrin (1983 : Brussels) ( 1984 )
Tetrachloroethylene / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization; World Health Organization; WHO Task Group on Environmental Health Criteria for Tetrachloroethylene (1983 : Brussels) ( 1984 )
Selenium / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation and the World Health Organization
International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization; World Health Organization ( 1987 )
Abstract

A richly detailed analysis of the many research issues surrounding the role of selenium as both an essential nutrient and a toxic element. The book opens with an analysis of what is known about the distribution of this ubiquitous element in the environment, including the natural presence of selenium in the food chain. Since food constitutes the main route of exposure for the general population, the book provides especially extensive coverage of levels typically found in different foods and the factors that can account for unusually high or low concentrations. Other sections cover the metabolism of selenium, discuss diseases in farm animals linked to either excessive or deficient intake, and summarize the results of experimental work on the physiological responses to toxicity and deficiency. Particular attention is given to the evaluation of past studies claiming a carcinogenic effect and more recent studies suggesting a protective effect against certain cancers in experimental animals

2,4-Dichlorophenoxyacetic acid (2,4-D / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
International Programme on Chemical Safety; United Nations Environment Programme; International Labour Organization; World Health Organization; IPCS Task Group on Environmental Health Criteria for 2,4-Dichlorophenoxyacetic Acid ( 1984 )