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|Title:||Barium / published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization|
|Authors:||World Health Organization|
International Programme on Chemical Safety
|Publisher:||Geneva : World Health Organization|
|Abstract:||Evaluates the risks to uman health and the environment posed by the mining, processing, and industrial use of barium. The opening sections review both natural and man-made sources of release into the environment, including nuclear fallout following the testing of weapons. A section devoted to environmental behaviour notes the contribution of industrial emissions, especially from the combustion of coal and diesel oil, to the presence of barium in air. Particular concern centres on concentrations found in water, where barium may have a residence time of several hundred years. Water supplies and food are identified as the most important routes of exposure for the general population. Other sections review what is known about the kinetics and metabolism of barium, discuss its capacity to mimic the role of calcium in many physiological processes, and consider effects on organisms in the environment, including effects on the infectivity of several viruses. The most extensive section evaluates experimental studies of barium toxicity, with particular attention given to reported effects on cardiovascular functions. The final section, devoted to effects on human health, evaluates findings from large-scale outbreaks of barium poisoning and from epidemiological studies designed to determine whether high barium concentrations in drinking-water are linked to disturbances in cardiovascular function. On the basis of these evaluations, the book concludes that barium poses no special risk for the general population. Potassium-deficient individuals, the elderly, exposed workers, and populations consuming high concentrations of barium in drinking water may experience adverse effects on health|
|Context:||adverse effects toxicity|
|metadata.dc.subject.other:||Chemical Toxicology and Carcinogenicity|
|Appears in Collections:||Publications|
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