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Measles vaccination coverage and seroprevalence of anti-measles antibody in south-east Islamic Republic of Iran

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Abstract
كثيراً ما توجد تباينات بين تغطية التطعيم المسجلة وبين المستوى الحقيقي للمناعة في المجتمع. ولتقدير تغطية التلقيح ضد الحصبة في جنوب شرق جمهورية إيران الإسلامية تم إجراء دراسة مقطعية في 3 مناطق خلال صيف عام 2011.فتم اختيار عينة عنقودية من 1368 طفلاً تتراوح أعمارهم ما بين 30-54 شهراً باستخدام الاحتمال المتناسب مع الحجم. وتم فحص عينات مصلية من 663 منهم - ممن تلقوا حقنتين من اللقاح الثلاثي ضد الحصبة والنكاف والحصبة الألمانية [‎MMR]‎- للتأكد من وجود الجلوبيولين المناعي G [‎IgG]‎المضاد للحصبة. لقد بلغت تغطية التطعيم بالجرعة الثانية من لقاح MMR 93.7%.وكان انتشار الجلوبيولين المناعي G المضاد للحصبة لدى أولئك الذين تلقوا جرعتين على الأقل من لقاح MMR 94.6%.وكان هناك ارتباط ذو دلالة إحصائية بين النتائج السيرولوجية وبين المتغيرات التي تعكس ضعف إمكانية الوصول إلى الخدمات الصحية. وبجمع النتائج السيرولوجية مع بيانات التغطية قُدِّرت نسبة الجمهور المحمي ضد الحصبة بـ 88.6%، والتي كانت أقل من الحدود المعينة لأهداف التخلص من الحصبة
Discrepancies often exist between recorded immunization coverage and the real immunity level in a community. To estimate the vaccination coverage against measles in south-east Islamic Republic of Iran, a crosssectional study was conducted in 3 districts during summer 2011. Using probability proportional to size cluster sampling, 1368 children aged 30–54 months were selected. Serum samples of 663 who had received 2 injections of mumpsmeasles-rubella (‎MMR)‎ vaccine were checked for anti-measles IgG. Vaccination coverage for the second dose of MMR vaccine was 93.7%. The prevalence of anti-measles IgG in those who had received at least 2 MMR vaccine doses was 94.6%. There was a statistically significant association between the serological results and variables that reflected poor accessibility to health services. Combining serological results with coverage data, the proportion of the community protected against measles was estimated as 88.6%, which was below the limits defined for the measles elimination goals.
Il existe souvent des écarts entre la couverture vaccinale enregistrée et le niveau réel d'immunité d'une communauté donnée. Afin d'estimer la couverture vaccinale antirougeoleuse dans le sud-est de la République islamique d'Iran, une étude transversale a été menée dans trois districts durant l'été 2011. En appliquant l'échantillonnage en grappes avec probabilité proportionnelle à la taille, 1368 enfants âgés de 30 à 54 mois ont été sélectionnés. Des prélèvements de sérum de 663 enfants de l'échantillonnage ayant reçu deux injections du vaccin contre la rougeole, les oreillons et la rubéole (‎ROR)‎ ont été analysés à la recherche d'anticorps IgG antirougeoleux. La couverture vaccinale pour la deuxième dose de vaccin ROR était de 93,7 %. La prévalence des anticorps IgG antirougeoleux chez les enfants ayant reçu au moins deux doses du vaccin ROR était de 94,6 %. Il existait une association statistiquement significative entre les résultats sérologiques et les variables qui reflétaient l'accès insuffisant aux services de santé. En combinant les résultats sérologiques et les données de couverture, la proportion de la communauté protégée contre la rougeole a été estimée à 88,6 %, soit un taux inférieur aux seuils définis pour les objectifs d'élimination de la rougeole.
Citation
Izadi, S., Azad, T.Mokhtari & Zahraei, S.M. (‎2015)‎. Measles vaccination coverage and seroprevalence of anti-measles antibody in south-east Islamic Republic of Iran. EMHJ-Eastern Mediterranean Health Journal, 21 (‎6)‎, 396 - 402. World Health Organization, Regional Office for the Eastern Mediterranean. http://www.who.int/iris/handle/10665/255110
Journal
EMHJ-Eastern Mediterranean Health Journal, 21 (‎6)‎: 396 - 402
ISSN
1020-3397
1687-1634 (‎Online ISSN)‎
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  • EMRO Journal Articles (‎EMHJ)‎
Language
English
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