Capillary leak syndrome in dengue fever.
AbstractCapillary leak syndrome (CLS) has been described in dengue fever but its exact features have not been clearly defined. We present here the findings in 25 cases of CLS recently seen by us during an outbreak of dengue fever in northern India. Besides fever, body ache and bleeding manifestations, ascites was present in 84% cases, pleural effusion in 76% cases, and both ascites and pleural effusion in 60% of cases. The pleural effusion was right-sided in 52.6% cases, bilateral in 47.4% cases and only left-sided in none of the cases. The fluid accumulation seen was moderate and frequently involved both abdomen and pleural cavity. The fluid rapidly cleared in a week’s time without any specific treatment. These cases can pose considerable diagnostic challenge which is discussed here.
Verma, Sudhir Kumar, Gutch, Manish, Agarwal, Abhishek & Vaish, AK. (2011). Capillary leak syndrome in dengue fever.. WHO Regional Office for South-East Asia.. http://www.who.int/iris/handle/10665/171018