Involvement of the liver in dengue infections.
AbstractDengue virus, the causative agent of dengue fever (DF) and more severe forms of the disease – dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS) – can infect a number of different types of cells. While monocytes and macrophages are considered to be primary target cells driving the pathology of the disease, numerous studies have implicated the liver as a site of dengue virus replication and both clinical observations and experimental data support a role of the liver in dengue disease. This review aims to provide a brief overview of the data supporting a role of the liver in the pathology of dengue disease
Smith, D. R. & Khakpoor, A. (2009). Involvement of the liver in dengue infections.. WHO Regional Office for South-East Asia.. http://www.who.int/iris/handle/10665/170941