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Title: Role of nitric oxide in the pathogenesis of dengue.
Authors: Anez, German
Valero, Nereida
Mosquera, Jesus
Issue Date: 2007
Publisher: WHO Regional Office for South-East Asia.
Place of publication: New Delhi
Language: English
Abstract: The free radical nitric oxide (NO) has emerged in recent years as a fundamental signalling molecule for the maintenance of homeostasis, as well as a potent cytotoxic effector involved in the pathogenesis of a wide range of human diseases. The presence of NO during dengue infection as well as its experimental antiviral and apoptotic effects have been documented. In this regard, increased serum NO levels in dengue fever and basal levels in the haemorrhagic form of dengue have been reported. Clinical and experimental data suggest that NO could act as a beneficial factor during dengue infection by its antiviral and apoptotic effects; however, more intense investigations are required.
Description: Dengue Bulletin. 2007 Dec; 31: 118-123.
Keywords: Dengue Hemorrhagic Fever
Dengue Virus
Nitric Oxide
URI: http://www.who.int/iris/handle/10665/170367
ISSN: 0250-8362
Appears in Collections:Dengue Bulletin



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