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  • Dengue Bulletin. 2016 Dec. Vol-39 

    World Health Organization, Regional Office for South-East Asia (‎2016)‎
  • Capillary leak syndrome in dengue fever. 

    Verma, Sudhir Kumar; Gutch, Manish; Agarwal, Abhishek; Vaish, AK (‎2011-12)‎
    Capillary leak syndrome (‎CLS)‎ has been described in dengue fever but its exact features have not been clearly defined. We present here the findings in 25 cases of CLS recently seen by us during an outbreak of dengue fever in northern India. Besides fever, body ache and bleeding manifestations, ascites was present in 84% cases, pleural effusion in 76% cases, and both ascites and pleural effusion in 60% of cases. The pleural effusion was right-sided in 52.6% cases, bilateral in 47.4% cases and only left-sided in none of the cases. The fluid ...
  • Haemogram profile of dengue fever in adults during 19 September – 12 November 2008: A study of 40 cases from Delhi. 

    Advani, Sonia; Agarwal, Shikha; Verma, Jitender (‎2011-12)‎
    Dengue illness appears similar to other febrile illnesses in its early stages, which means its diagnosis is often delayed or confused with other illnesses. To address this issue, we analysed the haemogram profile of 40 patients (‎>12 years)‎ hospitalized with DHF in Delhi from 19 September to 12 November 2008 to predict outbreaks and severity levels of the disease. Such studies could prove useful in disease management, diagnosing dengue and predicting the likelihood of haemorrhaging. All the patients were diagnosed, managed and monitored according ...
  • Involvement of the central nervous system in dengue fever and its outcome. 

    Kulkarni, ML; Kumar, Saurabh (‎2011-12)‎
    The involvement of the central nervous system in dengue-affected children, the spectrum of neurological manifestations and the presence of dengue-specific IgM antibodies in the cerebrospinal fluid (‎CSF)‎ was studied. A prospective study was conducted of all consecutive serum-positive dengue patients (‎n=100)‎ admitted to the hospitals attached to the Jagadguru Jayadeva Murugharajendra Medical College, Davangere, Karnataka state, India, from January 2009 to September 2010. Children who presented with neurological symptoms were grouped separately and ...
  • Differentiating early adult dengue from acute viral respiratory infections – A comparative analysis. 

    Thein, Tun-Linn; Ooi, Eng-Eong; Low, Jenny GH; Leo, Yee-Sin (‎2011-12)‎
    The clinical presentations of dengue disease in adults are not fully described. Differentiating dengue from other acute viral respiratory infections (‎ARIs)‎ is important. We conducted a prospective study from January 2008 to March 2010, recruiting subjects with early febrile illness presenting within the first 72 hours of illness at primary care outpatient clinics. This study evaluates cases enrolled to identify distinguishing clinical features of early dengue infection from ARIs. Acute and convalescent venous blood and nasal swab specimens were ...
  • Geographical association between socioeconomics and age of dengue haemorrhagic fever patients in Surabaya, Indonesia. 

    Nagao, Yoshiro; Rachmie, Esty M; Ochi, Shiro; Padmidewi, Maria M; Kuntarianto; Kawabata, Masato (‎2011-12)‎
    A study was designed to correlate the ages of dengue patients to the geographical and temporal demographic structure in 28 districts in Surabaya, Indonesia, between 1996 and 2005. The geographical distribution of the mean patient age was stable throughout the study period. The mean patient age did not correlate with the demographic structure but was related to the prevalence of poor housing where mosquito density was high. These results suggested that socioeconomic factors which affect mosquito abundance are more important determinants of the ...
  • Aedes aegypti indices and KAP study in Sangam Vihar, south Delhi, during the XIX Commonwealth Games, New Delhi, 2010. 

    Singh, RK; Mittal, PK; Yadav, NK; Gehlot, OP; Dhiman, RC (‎2011-12)‎
    Dengue fever (‎DF)‎ cases were reported in Delhi during August 2010. As the XIXth Commonwealth Games were to be held in Delhi in October 2010, entomological and community knowledge, attitude and practices (‎KAP)‎ studies were carried out to assist the Municipal Corporation of Delhi (‎MCD)‎ for better implementation of vector control activities in the city. A total of 495 houses were searched for Aedes aegypti breeding in all kinds of temporary and permanent water receptacles in both indoors and outdoors in a thickly-populated, illegally-constructed ...
  • Dengue Bulletin 

    Autor desconhecido (‎2010-12)‎
    The WHO Regional Office for South-East Asia, in collaboration with the Western Pacific Region, has been jointly publishing the annual Dengue Bulletin. The objective of the Bulletin is to disseminate updated information on the current status of DF/DHF infection, changing epidemiological patterns, new attempted control strategies, clinical management, information about circulating DENV strains and all other related aspects. The Bulletin also accepts review articles, short notes, book reviews and letters to the editor on DF/DHF-related subjects. ...
  • Cost and burden of dengue and chikungunya from the Americas to Asia. 

    Shepard, Donald S (‎2010-12)‎
    The ten studies in this special issue document the substantial and growing burden of dengue in the Americas, Africa and Asia, and the burden of a chikungunya outbreak in India. Luiz Tadeu Moraes Figuedo’s paper on dengue in Brazil confirms the country’s worsening trend from 1999–2009, where cases rose at 6.2% per year and dengue deaths at 12.0% per year. Carmen Perez and co-workers, reporting on dengue vector control in Puerto Rico, found that 83% of the costs (‎US$ 1.97 per person per year)‎ were funded by the lowest and often the least financed ...
  • Dengue in Brazil during 1999–2009: a review. 

    Figueiredo, Luiz Tadeu Moraes (‎2010-12)‎
    Over the period 1999 through 2009, the incidence of dengue in Brazil has shown an upward trend with more than 700 000 cases per year reported during 2002 and 2008. Despite efforts to control Aedes aegypti, a hyper-endemic situation has remained with large outbreaks involving all the four dengue serotypes (‎DENV-1 to 4)‎. The average age of DHF/DSS cases has decreased, making it a disease affecting children. The number of fatalities has also increased. While other countries in the Americas have also witnessed an upward trend in case numbers, Brazil ...
  • Economic cost of dengue public prevention activities in Puerto Rico. 

    Pérez-Guerra, Carmen L; Halasa, Yara A; Rivera, Reinaldo; Peña, Marisol; Ramírez, Viani; Cano, Martha Patricia; Shepard, Donald S; Puerto Rico (‎2010-12)‎
    Dengue fever has become a major global public health problem in Puerto Rico. Approximately 5000 suspected cases were reported annually between 2002 and 2007. Vector control is currently the only approach to control the disease and includes prevention education, fumigation, inspections and clean-up campaigns. The annual cost to the public sector of dengue prevention, which includes surveillance and vector control activities, was estimated as part of a study of the economic burden of dengue in Puerto Rico. A telephonic survey was implemented to ...
  • Preliminary estimate of immediate cost of chikungunya and dengue to Gujarat, India. 

    Murtola, Tiina M; Vasan, SS; Puwar, Tapasvi I; Govil, Dipti; Field, Robert W; Gong, Hong-Fei; Bhavsar-Vyas, Ami; Suaya, Jose A; Howard, Marion; Shepard, Donald S; Kohli, Vijay Kumar; Prajapati, PB; Singh, Amarjit; Mavalankar, Dileep V; Chikungunya (‎2010-12)‎
    This study aims to provide a preliminary estimate of the immediate cost of chikungunya and dengue to household in the Indian state of Gujarat. Combining nine earlier studies and data from interviews, we analysed the costs of non-fatal illness and of intervention programmes; building a more comprehensive picture of the immediate cost of these Aedes aegypti mosquito-borne diseases to Gujarat. The “RUHA matrix” was used to estimate the cost of illness by combining the shares of reported (‎R)‎ and unreported (‎U)‎ hospitalized (‎H)‎ and ambulatory (‎A)‎ cases ...
  • Prevalence of chikungunya in the city of Ahmedabad, India, during the 2006 outbreak: a community-based study. 

    Puwar, Tapasvi; Sheth, Jay K; Kohli, Vijay; Yadav, Rajpal (‎2010-12)‎
    Prevalence of chikungunya in the city of Ahmedabad, India during the 2006 outbreak was investigated to estimate the prevalence of suspected chikungunya cases to find out demographic parameters and proportion of various symptoms among suspected chikungunya cases, and to evaluate the effectiveness of control measures implemented by the public health sector. A total of 6667 people from 1301 households were surveyed. The prevalence of suspected chikungunya cases was 32.9% (‎31.8% – 34.2%)‎. Prevalence was higher in females (‎p
  • Prevalence of various symptoms and cost of treatment during the chikungunya epidemic in Ahmedabad, Gujarat, India, in 2006. 

    Mavalankar, Dileep; Govil, Dipti; Trivedi, Neha; Patel, Vinubhai (‎2010-12)‎
    Ahmedabad city in the State of Gujarat was one of the cities most affected by an epidemic of chikungunya. This paper attempts to document the epidemiological profile of chikungunya cases in the city of Ahmedabad in 2006. It also tries to study the economic burden of the disease on patients and understand their treatment-seeking behaviour. There was an average of 2.4 suspected chikungunya patients in a family of five members. Mean duration of illness was 19 days. Thirteen per cent of those suffering from chikungunya were admitted to hospital. The ...
  • A private hospital-based study assessing knowledge, attitudes, practices and costs associated with dengue illness in Surat, India. 

    Bhavsar, Ami T; Shepard, Donald S; Suaya, Jose A; Mafowosofo, Moses; Hurley, Clare L (‎2010-12)‎
    We conducted a descriptive cross-sectional study at a private children’s and general hospital in Surat,India, during the 2006 dengue season (‎June to December 2006)‎. We examined knowledge, attitudes and practices of patients associated with dengue and estimated the cost of a dengue episode for the study sample. Of 62 patients with suspected dengue, 40 consented to participate in this study. We interviewed 27 retrospectively in their homes and 13 prospectively during their hospitalization. Among the respondents, 75% were male, 85% were under the ...
  • Immediate cost of dengue to Malaysia and Thailand: an estimate. 

    Lee Han, Lim; Vasan, SS; Birgelen, L; Murtola, TM; Gong, HF; Field, Robert W; Mavalankar, Dileep V; Ahmad, Nazni Wasi; Hakim, Lokman S; Murad, Shahnaz; Ng Chiu, Wan; Lucy Lum Chai, See; Suaya, Jose A; Shepard, Donald S (‎2010-12)‎
    We have analysed the average annual cost of dengue in Malaysia during the period 2002–2007 and in Thailand between 2000 and 2005. The key cost components, estimated by combining existing data from both published and unpublished studies, consist of: (‎i)‎ costs of non-fatal illness; (‎ii)‎ vector (‎Aedes mosquitoes)‎ control costs; and (‎iii)‎ research and development (‎R&D)‎ costs incurred by government institutions. We found the immediate cost of dengue to Malaysia to be in the range of US$ 88 million to US$ 215 million (‎mean US$ 133 million)‎ per annum. ...
  • Cost of dengue in Thailand. 

    Kongsin, Sukhontha; Jiamton, Sukhum; Suaya, Jose A; Vasanawathana, Sirijitt; Sirisuvan, Petcherut; Shepard, Donald S (‎2010-12)‎
    The burden of hospitalized dengue cases in Thailand is high. In Khon Kaen Hospital, a provincial hospital, the cost per non-fatal case in 2005 averaged (‎±standard deviation)‎ US$ 573 (‎±351)‎. The majority of this cost is incurred by the government, indicating the importance of dengue to public policy. The projected national cost is US$ 158 (‎±33)‎ million or US$ 3.55 (‎±$0.53)‎ per capita per year. In international dollars, which adjust for purchasing power parity, the annual cost is 485 (‎±106)‎ million international dollars. Of this total, 28% is for ...
  • Clinical characterization, diagnosis and socioeconomic impact of hospitalized dengue in Cambodia. 

    Suaya, Jose A; Chantha, Ngan; Huy, Rekol; Sah, Binod K; Moh-Seng, Chang; Socheat, Duong; Buchy, Philippe; Vantha, Te; Sivuth, Ong; Haileselassie, Elizabeth; Shepard, Donald S (‎2010-12)‎
    Dengue infection is endemic among children in Cambodia. Few studies have described the clinical characteristics, diagnoses and the socioeconomic impact of hospitalized dengue cases. As part of a multicountry prospective dengue study, we analysed interviews and record reviews of 123 consecutive cases of children hospitalized with confirmed dengue in a major public provincial hospital. About 80% of cases evidenced plasma leak. On average, a hospitalized dengue case lasted 6.3 days, with 3.3 days of inpatient care, and cost US$116 (‎Singapore dollar ...
  • Increase in dengue fever imported from Côte d’Ivoire and West Africa to France. 

    Ruche, Guy La; Renaudat, Charlotte; Tarantola, Arnaud; Caro, Valérie; Ledrans, Martine; Dejour-Salamanca, Dominique; Diancourt, Laure; Tolou, Hugues; Grandadam, Marc; Gastellu-Etchegorry, Marc (‎2010-12)‎
    Dengue is usually not considered a significant health problem in Africa because severe forms of dengue illness are rarely reported. In the absence of local surveillance data, the investigation of dengue cases imported to France contributed to document the circulation of dengue virus in this area. From 1 July 2006 to 31 December 2008, a total of 148 dengue cases imported to metropolitan France were reported through the mandatory notification system. Arthralgia and signs of severity (‎haemorrhage, thrombocytopenia)‎ were less frequent in patients ...
  • Detection of insecticide resistance in Aedes aegypti to organophosphate and synthetic pyrethroid compounds in the north-east of Thailand. 

    Pimsamarn, S.; Sornpeng, W.; Akksilp, S.; Paeporn, P; Limpawitthayakul, M (‎2009-12)‎
    Aedes aegypti is a vector of dengue fever, which is a public health problem in the north-east of Thailand. During epidemics, emphasis is laid on the use of insecticides for the control of the disease. A survey of insecticides used was carried out in eight provinces, namely Amnat Charoen, Kalasin, Mukdahan, Nakhon Phanom, Sakon Nakhon, Si Sa Ket, Ubon Ratchathani and Yasothon. The study indicated that temephos was the only chemical used for the control of mosquito larvae while cypermethrin was used as space spray for the control of adult mosquitoes. ...

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