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Title: Antiphospholipid syndrome and retinal vein occlusion in adults
Authors: Maaroufi, R.M.
Hamdi, R.
Jmili, N.
Ghorbal, M.
Hamida, Bel Hadj F.
Mahjoub, T.
Issue Date: 2004
Language: English
Abstract: Antiphospholipid antibodies may play and important role in the pathogenesis of retinal vascular occlusions; investigated the prevalence among 33 patients with retinal vein and artery occlusions and 80 controls. Prevalence was 33% and 5% respectively. Ophthalmic examination and fluorescein angiography showed that occlusions were due to ischaemic events. The 11 patients were diagnosed with antiphospholipid syndrome: 9 patients were treated successfully with laser photocoagulation and anticoagulant and anti-aggregant therapy. Two patients with antiphospholipid antibodies associated with resistance to activated protein C had unfavourable outcomes. Our results suggest a correlation between antiphospholipid syndrome and retinal vein occlusions; we recommend a systematic search for antiphospholipid antibodies in occlusions of unexplained origin and laser photocoagulation treatment and long-term oral anticoagulant and anti-aggregant therapy
Description: 627-632
Keywords: Administration, Oral
Antibodies, Antiphospholipid
Case-Control Studies
Chi-Square Distribution
Fluorescein Angiography
Laser Coagulation
Retinal Vein Occlusion
Subject: Antiphospholipid Syndrome
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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