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Title: Ceftriaxone versus ampicillin/cloxacillin as antibiotic prophylaxis in elective caesarean section
Authors: Ahmed, E.T.S.
Mirghani, O.A.
Gerais, A.S.
Adam, I.
Issue Date: 2004
Language: English
Abstract: We carried out a prospective, r and omized, controlled clinical trial to evaluate the clinical efficacy of ceftriaxone and ampicillin/cloxacillin prophylaxis in decreasing the frequency of post-caesarean section infection-related morbidity. Two hundred patients randomly received either ceftriaxone [single dose] or ampicillin/cloxacillin [3 doses] intravenously at induction of anaesthesia. There was no statistical difference in incidence of endometritis [P = 0.34], wound infection [P = 0.44], or other febrile morbidity [P = 0.5]. Eleven babies had a low Apgar score [< 8] in the ceftriaxone group and 13 in the ampicillin/cloxacillin group [P = 0.82].There were 2 perinatal deaths in each group. One dose of ceftriaxone was as effective as ampicillin/ cloxacillin in preventing post-caesarean section complications and is easier to administer
Description: 277-282
Keywords: Apgar Score
Cross Infection
Hospitals, Teaching
Subject: Ampicillin
ISSN: 1020-3397
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Appears in Collections:EMRO Journal Articles (EMHJ)

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