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Title: Quinine therapy in severe Plasmodium falciparum malaria during pregnancy in Sudan
Authors: Adam, I.
Mirghani, O.A.
Saed, O.K.
Ahmed, S.M.
Mohamadani, A.A.
Ahmed, H.M.
Mackenzie, C.D.
Homeida, M.M.A.
El Bashir, M.I.
Issue Date: 2004
Language: English
Abstract: A prospective study was carried out in an area of unstable malaria transmission in central Sudan to determine the efficacy and toxicity of quinine in pregnancy. Thirty-three pregnant women with severe Plasmodium falciparum malaria at mean 28.8 weeks gestational age were treated with quinine for 7 days. The mean body temperature on presentation for 3 patients who delivered prematurely was significantly higher than for those who delivered at term [39.2 +/- 0.7 degrees C versus 38.7 +/- 1.3 degrees C]. There were no significant difference between the 2 groups in other clinical or biochemical parameters. There were no clinically detectable congenital malformations and no auditory, visual or other neurological deficits in the babies at birth or 6 months later. Quinine may be safe in the treatment of severe falciparum malaria during pregnancy
Description: 159-166
Keywords: Administration, Oral
Body Temperature
Drug Administration Schedule
Gestational Age
Infusions, Intravenous
Pregnancy Outcome
Subject: Antimalarials
ISSN: 1020-3397
Other Identifiers:
Appears in Collections:EMRO Journal Articles (EMHJ)

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