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Title: Outcome of azithromycin treatment of active trachoma in Omani schoolchildren
Authors: Khandekar, R.
Mohammed, A.J.
Issue Date: 2003
Language: English
Abstract: A prospective cohort study was made of 386 first-grade primary-school children in Oman with active trachoma and 386 matched controls without trachoma. All children were educated about trachoma prevention. In addition, trachoma cases were treated with a single dose of oral azithromycin [20 mg/kg]. Trachoma status was evaluated after 6 weeks, 6 months and 12 months. The follicles and inflammatory signs of active trachoma resolved 6 weeks or more after azithromycin treatment. The protection against subsequent trachoma infection cycles was optimal at 6 months [85.2% of cases, 99.0% of controls infection-free] but declined at 12 months [66.7% of cases, 98.2% of controls infection-free]. Clinical evaluation seems to be a useful tool to evaluate the response of azithromycin to active trachoma cases in schoolchildren in a country with limited resources
Description: 1026-1033
Keywords: Administration, Oral
Anti-Bacterial Agents
Drug Administration Schedule
Mass Screening
Physical Examination
School Health Services
Single-Blind Method
Time Factors
Trachoma
Treatment Outcome
Subject: Azithromycin
URI: http://www.who.int/iris/handle/10665/119358
ISSN: 1020-3397
Other Identifiers: http://applications.emro.who.int/emhj/0905_6/9_5-6_2003_1026_1033.pdf
Appears in Collections:EMRO Journal Articles (EMHJ)



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