Visceral leishmaniasis in the Syrian Arab Republic: early detection using rK39
AbstractLeishmaniasis causes significant morbidity and mortality in areas where it is endemic. A seroprevalence survey was conducted in 2 endemic villages in Daraa, Syrian Arab Republic, where 80 out of 345 children [23.2%] tested positive for visceral leishmaniasis [VL] using rK39 dipstick test. Only 10 cases were symptomatic [12.5%], and 27.5% were positive by ELISA test. All the sera [N = 138] obtained from the control village were negative. Of the rK39 initially positive cases, 52 had seroconverted to negative 9 months later, 55 remained ELISA negative, and none developed the full-blown disease. Being faster and less expensive than other diagnostic tests, rK39 is a rapid, sensitive and specific diagnostic tool for symptomatic cases of VL in remote areas with poor accessibility to health services
Al Nahhas, S., Shabaan, M., Hammoud, L., Al Taweel, A. & Al Jorf, S. (2003). Visceral leishmaniasis in the Syrian Arab Republic: early detection using rK39. http://www.who.int/iris/handle/10665/119340
EMHJ - Eastern Mediterranean Health Journal, 9 (4), 856-862, 2003
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