|Title:||Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan|
|Authors:||El Safi, S.H.|
Abdel Haleem, A.
El Basha, I.
|Abstract:||A latex agglutination test to detect urinary antigens for visceral leishmaniasis [VL] was studied. In 204 patients with suspected VL, KAtex had a sensitivity of 95.2% with good agreement with microscopy smears but poor agreement with 4 different serology tests. It was also positive in 2 confirmed VL cases co-infected with HIV. In all KAtex-positive confirmed cases actively followed up after treatment, the test became negative 1 month after completion of treatment. While KAtex had a specificity of 100% in healthy endemic and non-endemic controls, the direct agglutination test [DAT] was positive in 14% of the KAtex-negative healthy endemic controls. KAtex is a simple addition to the diagnostics of VL particularly at field level and as a complementary test for the diagnosis of VL in smear-negative cases with positive DAT results|
Enzyme-Linked Immunosorbent Assay
Fluorescent Antibody Technique, Indirect
Latex Fixation Tests
|Appears in Collections:||EMRO Journal Articles (EMHJ)|
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